Citation: YANG Ting, ZHOU Ying, WANG Ning, CHEN Ming-Li, WANG Jian-Hua. Preparation of Silicon and Boron-doped Carbon Dots and Their Application in Hemoglobin Sensing[J]. Chinese Journal of Analytical Chemistry, ;2017, 45(12): 1996-2003. doi: 10.11895/j.issn.0253-3820.171270 shu

Preparation of Silicon and Boron-doped Carbon Dots and Their Application in Hemoglobin Sensing

Research Center for Analytical Sciences, Department of Chemistry, College of Sciences, Northeastern University, Shenyang 110819, China

Corresponding author: CHEN Ming-Li, chenml@mail.neu.edu.cn WANG Jian-Hua, jianhuajrz@mail.neu.edu.cn
Received Date: 26 September 2017
Accepted Date: 27 October 2017

Fund Project: the Open Funds of the State Key Laboratory of Electroanalytical Chemistry SKLEAC201702the Fundamental Research Funds for the Central Universities N141008001Natural Science Foundation of China 21235001the Fundamental Research Funds for the Central Universities N160504008Natural Science Foundation of China 21405010Natural Science Foundation of China 21675019Natural Science Foundation of China 21375013This work was supported by Natural Science Foundation of China (Nos. 21235001, 21405010, 21675019, 21375013), the Fundamental Research Funds for the Central Universities (Nos. N160504008, N141008001) and the Open Funds of the State Key Laboratory of Electroanalytical Chemistry (No. SKLEAC201702)

Figures(9)

Heteroatom doping is an effective way to elevate the fluorescent performance of carbon dots. In this study, a microwave one-pot approach for the synthesis of SiBCDs was proposed by using citric acid (C₆H₈O₇), boric acid (H₃BO₃) and (3-aminopropyl) triethoxy sliane (APTES) as source materials. PAAS-SiBCDs were prepared with the assistance of microwave when sodium polyacrylate (PAAS) was added in the precursor of SiBCDs. The products were characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS) and Fourier transform infrared (FT-IR) spectra, respectively, confirming that the product was amorphous CDs, with small amount of Si and B. The synthesized SiBCDs had good monodispersity with size of 4-8 nm, the average size of PAAS-SiBCDs was 5.2 nm, and the excitation/emission maximum was 350 nm/445 nm. The quantum yield of SiBCDs was 20.1%, and that of PAAS-SiBCDs was 34.6%. Based on the quenching effect of hemoglobin (Hb) on the fluorescence PAAS-SiBCDs, a sensitive Hb detection method was developed. A linear range of 0.21-5.22 μmol/L was obtained together with a detection limit of 0.06 μmol/L. The method was applied in the determination of Hb in human blood samples.
- Carbon dots,
- Silicon and boron dopping,
- Hemoglobin,
- Sensing
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