Citation: MA Xiao-Ming, SUN Mi, LIN Yue, LIU Yin-Jin, LUO Fang, GUO Long-Hua, QIU Bin, LIN Zhen-Yu, CHEN Guo-Nan. Progress of Visual Biosensor Based on Gold Nanoparticles[J]. Chinese Journal of Analytical Chemistry, ;2018, 46(1): 1-10. doi: 10.11895/j.issn.0253-3820.171054 shu

Progress of Visual Biosensor Based on Gold Nanoparticles

MA Xiao-Ming ^1,2, ,
SUN Mi ¹ ,
LIN Yue ¹ ,
LIU Yin-Jin ¹ ,
LUO Fang ¹ ,
GUO Long-Hua ¹ ,
QIU Bin ¹ ,
LIN Zhen-Yu ¹ ,
CHEN Guo-Nan ¹

1.
Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, and Department of Chemistry, Fuzhou University, Fuzhou 350108, China;2 Gannan Normal University, College of Chemistry and Chemical Engineering, Ganzhou 341000, China

Received Date: 1 July 2017
Revised Date: 20 September 2017

Fund Project: This work was supported by the National Natural Science Foundation of China (Nos. 21575027, 21575025)

Visualization detection methods are used for determination of the concentration of unknown target by comparing the color change in the intensity or type of reaction solution by naked eye. Visualization detection method has some advantages such as simple and rapid operation, low detection cost, fast reaction speed, and detecting target concentration by means of naked eye. Gold nanomaterials are widely used in the construction of visual biosensors due to its unique optical properties. For example, when changing the distance or morphology of the particles, the plasmon resonance absorption peak of local surface will change accordingly. Herein, we reviewed the application of gold nanomaterials in visualization biosensors for the detection of target molecules, summed up the main problems of AuNP colormertic methods in the determination of actual samples, and provided an outlook of the future of gold nanoparticles-based biosensor in application development.
- Gold nanoparticles,
- Visualization biosensor,
- Review
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