Citation: Chao He, Wanpin Yu, Qingyuan Zhao, Huina Liu, Yu Wang, Yue Xiong, Yuqing Zeng, Jing Zhao, Zhi Ping Xu, Lingxiao Zhang. Exosomes shape inflammatory tumor microenvironment[J]. Chinese Chemical Letters, ;2026, 37(9): 111900. doi: 10.1016/j.cclet.2025.111900 shu

Exosomes shape inflammatory tumor microenvironment

Chao He ^{a, b, 1} ,
Wanpin Yu ^{a, 1} ,
Qingyuan Zhao ^{a, 1} ,
Huina Liu ^a ,
Yu Wang ^b ,
Yue Xiong ^c ,
Yuqing Zeng ^c ,
Jing Zhao ^b ,
Zhi Ping Xu ^{a, b, c, *,} ,
Lingxiao Zhang ^{a, b, d, *,}

a.
School of Medicine, Hangzhou City University, Hangzhou 310015, China
b.
Institute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen 518107, China
c.
School of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China
d.
Interdisciplinary Nanoscience Center, Aarhus University, Aarhus C 8000, Denmark

gordonxu@szbl.ac.cn

zhanglx@inano.au.dk

Received Date: 27 May 2025
Revised Date: 22 September 2025
Accepted Date: 24 September 2025
Available Online: 25 September 2025

Figures(4)

The pervasive inflammatory response orchestrates every stage of tumor initiation and progression, not only serving as a catalyst for tumorigenesis but also as a nurturing environment for malignant growth. Within this intricate microenvironment teeming with cancer cells, immune cells, and stromal cells, a continuous exchange of inflammatory signals mediated by exosomes, small membrane-bound vesicles guide the development of the proinflammatory tumor microenvironment (TME). In this review, we delve into the intricate dialogue mechanisms among tumor cells, resident immune cells and stromal cells, scrutinizing the roles of exosomes derived from both tumor cells and other resident cells in shaping the inflammatory milieu. Anti-tumor therapies harnessing the diverse compositions and effects of exosomes have unveiled novel strategies for combating tumor malignancy.
- Inflammatory tumor microenvironment,
- Exosomes,
- Cellular communication,
- Education and crosstalk,
- Pro-tumor and anti-tumor
1. [1]
  R. Baghban, L. Roshangar, R. Jahanban-Esfahlan, et al., Cell Commun. Signal. 18 (2020) 59. doi: 10.1186/s12964-020-0530-4
2. [2]
  M. Barroux, J. Househam, E. Lakatos, et al., Nat. Cancer 6 (2025) 820–837. doi: 10.1038/s43018-025-00955-w
3. [3]
  X. Wu, F. Yan, L. Wang, et al., Front. Cell Dev. Biol. 8 (2020) 812. doi: 10.3389/fcell.2020.00812
4. [4]
  K.E. de Visser, J.A. Joyce, Cancer Cell 41 (2023) 374–403. doi: 10.1016/j.ccell.2023.02.016
5. [5]
  P. Nallasamy, R.K. Nimmakayala, S. Parte, et al., Mol. Cancer 21 (2022) 225. doi: 10.1186/s12943-022-01682-x
6. [6]
  J. Wang, Q. Zhang, Y. Li, et al., Chin. Chem. Lett. 35 (2024) 108746. doi: 10.1016/j.cclet.2023.108746
7. [7]
  H. Que, Q. Fu, T. Lan, et al., Biochim. Biophys. Acta Rev. Cancer 1877 (2022) 188762. doi: 10.1016/j.bbcan.2022.188762
8. [8]
  S. Yuan, R. Sun, H. Shi, et al., Nature 640 (2025) 1062–1071. doi: 10.1038/s41586-025-08732-6
9. [9]
  S. Wang, Y. Shi, Int. J. Nanomed. 17 (2022) 6527–6550. doi: 10.2147/ijn.s388604
10. [10]
  G. Wang, J. Li, L. Bojmar, et al., Nature 618 (2023) 374–382. doi: 10.1038/s41586-023-06114-4
11. [11]
  S. Li, R. Dong, Z. Kang, et al., Cytokine Growth Factor Rev. 73 (2023) 93–100. doi: 10.1016/j.cytogfr.2023.06.005
12. [12]
  K.S. Park, C. Lässer, J. Lötvall, Physiol. Rev. 105 (2025) 1733–1821. doi: 10.1152/physrev.00032.2024
13. [13]
  Y. Zhao, L. Gao, J. Chen, et al., Cell Metab. 37 (2025) 886–902 e887. doi: 10.3390/brainsci15080886
14. [14]
  R. Kou, T. Li, C. Fu, et al., Environ. Res. 244 (2024) 117783. doi: 10.1016/j.envres.2023.117783
15. [15]
  Y. Sun, B. Li, B. Song, et al., J. Nanobiotechnol. 23 (2025) 204. doi: 10.1186/s12951-025-03246-9
16. [16]
  I.Z.A. Pawluczyk, J.S. Bhachu, J.R. Brown, et al., Kidney Int. 108 (2025) 119–135. doi: 10.1016/j.kint.2025.03.019
17. [17]
  L. Wang, H. Fu, G. Nanayakkara, et al., J. Hematol. Oncol. 9 (2016) 122. doi: 10.1186/s13045-016-0351-5
18. [18]
  Y. Tian, C. Cheng, Y. Wei, et al., Cells 11 (2022) 1005. doi: 10.3390/cells11061005
19. [19]
  I. Li, B.Y. Nabet, Mol. Cancer 18 (2019) 32. doi: 10.31392/npu-nc.series14.2019.27.05
20. [20]
  J.H. Jang, D.H. Kim, Y.J. Surh, NPJ Precis. Oncol. 5 (2021) 18. doi: 10.1038/s41698-021-00154-7
21. [21]
  C. Li, Y.-Q. Ni, H. Xu, et al., Signal Transduct. Tar. 6 (2021) 383. doi: 10.1177/09516298211027229
22. [22]
  Y. Zhou, Y. Zhang, H. Gong, et al., Int. J. Mol. Sci. 22 (2021) 12204. doi: 10.3390/ijms222212204
23. [23]
  K. Gao, J. Jin, C. Huang, et al., Front. Immunol. 10 (2019) 1560. doi: 10.3389/fimmu.2019.01560
24. [24]
  H. Zhou, M. Zhou, X. Liao, et al., Adv. Sci. 12 (2025) 2413675. doi: 10.1002/advs.202413675
25. [25]
  A.M. Soliman, D.R. Barreda, Int. J. Mol. Sci. 24 (2022) 641. doi: 10.3390/ijms24010641
26. [26]
  K.M. Sheu, A. Hoffmann, Annu. Rev. Immunol. 40 (2022) 295–321. doi: 10.1146/annurev-immunol-101320-031555
27. [27]
  Y. Wen, S.D. Crowley, Curr. Opin. Nephrol. Hypertens. 29 (2020) 286–292. doi: 10.1097/mnh.0000000000000595
28. [28]
  S. Lee, S. Huen, H. Nishio, et al., J. Am. Soc. Nephrol. 22 (2011) 317–326. doi: 10.1681/ASN.2009060615
29. [29]
  G. Tezcan, N. Yakar, H. Hasturk, et al., Periodontol. 2000 96 (2024) 229–249. doi: 10.1111/prd.12603
30. [30]
  C. Mella, P. Tsarouhas, M. Brockwell, H.C. Ball, Cancers (Basel) 17 (2025) 154. doi: 10.3390/cancers17010154
31. [31]
  F.R. Greten, S.I. Grivennikov, Immunity 51 (2019) 27–41. doi: 10.1016/j.immuni.2019.06.025
32. [32]
  F. Liu, L. Li, M. Lan, et al., Mediators Inflamm. 2021 (2021) 7785890. doi: 10.1155/2021/7785890
33. [33]
  W. Song, R. Mazzieri, T. Yang, G.C. Gobe, Front. Immunol. 8 (2017) 1106. doi: 10.3389/fimmu.2017.01106
34. [34]
  L.M. Coussens, Z. Werb, Nature 420 (2002) 860–867. doi: 10.1038/nature01322
35. [35]
  J. Borowczak, K. Szczerbowski, M. Maniewski, et al., Biomedicines 10 (2022) 1670. doi: 10.3390/biomedicines10071670
36. [36]
  V. Infantino, A. Santarsiero, P. Convertini, et al., Int. J. Mol. Sci. 22 (2021) 5703. doi: 10.3390/ijms22115703
37. [37]
  E.E. Wicks, G.L. Semenza, J. Clin. Invest. 132 (2022) e159839. doi: 10.1172/JCI159839
38. [38]
  Z. Yang, W. Su, X. Wei, et al., Cell Rep. 42 (2023) 112945. doi: 10.1016/j.celrep.2023.112945
39. [39]
  S. Ma, Y. Zhao, W.C. Lee, et al., Nat. Commun. 13 (2022) 4118. doi: 10.1038/s41467-022-31764-9
40. [40]
  R.A. Castillo-Rodríguez, C. Trejo-Solís, A. Cabrera-Cano, et al., Cancers (Basel) 14 (2022) 2291. doi: 10.3390/cancers14092291
41. [41]
  S.R. Kim, K.J. Seong, W.J. Kim, J.Y. Jung, Int. J. Mol. Sci. 23 (2022) 4004. doi: 10.3390/ijms23074004
42. [42]
  S. Rastogi, S. Aldosary, A.S. Saeedan, et al., Front. Pharmacol. 14 (2023) 1108915. doi: 10.3389/fphar.2023.1108915
43. [43]
  X. Wu, Y. Chen, W. He, et al., Cell. Oncol. 48 (2025) 637–654. doi: 10.1007/s13402-025-01037-w
44. [44]
  K. Balamurugan, Int. J. Cancer 138 (2016) 1058–1066. doi: 10.1002/ijc.29519
45. [45]
  H. Huang, S. Zhang, Y. Li, et al., Nat. Commun. 12 (2021) 3720. doi: 10.1038/s41467-021-24108-6
46. [46]
  M. Bai, P. Xu, R. Cheng, et al., Oncogene 44 (2025) 1609–1619. doi: 10.1038/s41388-025-03336-w
47. [47]
  S. Sriramkumar, R. Sood, T.D. Huntington, et al., J. Transl. Med. 20 (2022) 246. doi: 10.1186/s12967-022-03447-y
48. [48]
  T. Hussain, B. Tan, Y. Yin, et al., Oxid. Med. Cell. Longev. 2016 (2016) 7432797. doi: 10.1155/2016/7432797
49. [49]
  M.J. Iqbal, A. Kabeer, Z. Abbas, et al., Cell Commun. Signal. 22 (2024) 7. doi: 10.1186/s12964-023-01398-5
50. [50]
  S. Wang, X. Liu, D. Wei, et al., J. Am. Chem. Soc. 146 (2024) 30033–30045. doi: 10.1021/jacs.4c06338
51. [51]
  K.G. de la Cruz-López, L.J. Castro-Muñoz, D.O. Reyes-Hernández, et al., Front. Oncol. 9 (2019) 1143. doi: 10.3389/fonc.2019.01143
52. [52]
  M. Certo, C.H. Tsai, V. Pucino, et al., Nat. Rev. Immunol. 21 (2021) 151–161. doi: 10.1038/s41577-020-0406-2
53. [53]
  L.B. Ivashkiv, Nat. Rev. Immunol. 20 (2020) 85–86. doi: 10.1038/s41577-019-0259-8
54. [54]
  J. Qu, P. Li, Z. Sun, Front. Immunol. 14 (2023) 1284344. doi: 10.3389/fimmu.2023.1284344
55. [55]
  C. Manosalva, J. Quiroga, A.I. Hidalgo, et al., Front. Immunol. 14 (2022) 808799.
56. [56]
  S. Chen, W. Cui, Z. Chi, et al., Cell Metab. 34 (2022) 1843–1859 e1811. doi: 10.3390/molecules27061843
57. [57]
  Y. Liu, J. Wang, M. Jiang, Front. Immunol. 14 (2023) 1145080. doi: 10.3389/fimmu.2023.1145080
58. [58]
  L. Cui, A.M. Gouw, E.L. LaGory, et al., Nat. Biotechnol. 39 (2021) 357–367. doi: 10.1038/s41587-020-0707-9
59. [59]
  Q. Zhou, Y. Zhang, L. Lu, et al., Food Chem. Toxicol. 168 (2022) 113369. doi: 10.1016/j.fct.2022.113369
60. [60]
  A. Flemming, Nat. Rev. Immunol. 23 (2023) 344-344. doi: 10.1038/s41577-023-00889-3
61. [61]
  H. Zhao, L. Wu, G. Yan, et al., Signal Transduct. Tar. 6 (2021) 263.
62. [62]
  K. Miao, W. Liu, J. Xu, et al., Front. Immunol. 14 (2023) 1277243. doi: 10.3389/fimmu.2023.1277243
63. [63]
  A. Robinson, C.Z. Han, C.K. Glass, J.W. Pollard, Trends Immunol. 42 (2021) 104–119. doi: 10.1016/j.it.2020.12.001
64. [64]
  A. Mezheyeuski, M. Backman, J. Mattsson, et al., EBioMedicine 88 (2023) 104452. doi: 10.1016/j.ebiom.2023.104452
65. [65]
  Q. Yang, N. Guo, Y. Zhou, et al., Acta Pharm. Sin. B 10 (2020) 2156–2170. doi: 10.1016/j.apsb.2020.04.004
66. [66]
  H. Li, Y. Meng, S. He, et al., Cells 11 (2022) 3001. doi: 10.3390/cells11193001
67. [67]
  O.M. Rahal, A.R. Wolfe, P.K. Mandal, et al., Int. J. Radiat. Oncol. 100 (2018) 1034–1043. doi: 10.1016/j.ijrobp.2017.11.043
68. [68]
  X. Zhou, X. Liu, L. Huang, Adv. Funct. Mater. 31 (2021) 2006220. doi: 10.1002/adfm.202006220
69. [69]
  A.J. Boutilier, S.F. Elsawa, Int. J. Mol. Sci. 22 (2021) 6995. doi: 10.3390/ijms22136995
70. [70]
  J. Jiang, J. Mei, Y. Ma, et al., Exploration 2 (2022) 20210144. doi: 10.1002/EXP.20210144
71. [71]
  A. Christofides, L. Strauss, A. Yeo, et al., Nat. Immunol. 23 (2022) 1148–1156. doi: 10.1038/s41590-022-01267-2
72. [72]
  C. Lee, H. Jeong, Y. Bae, et al., J. Immunother. Cancer 7 (2019) 147. doi: 10.1186/s40425-019-0610-4
73. [73]
  V.C. Brom, C. Burger, D.C. Wirtz, F.A. Schildberg, Front. Immunol. 13 (2022) 837645. doi: 10.3389/fimmu.2022.837645
74. [74]
  M. Yan, M. Zheng, R. Niu, et al., Front. Cell Dev. Biol. 10 (2022) 938289. doi: 10.3389/fcell.2022.938289
75. [75]
  S. Wang, G. Liu, Y. Li, Y. Pan, Front. Immunol. 13 (2022) 840029. doi: 10.3389/fimmu.2022.840029
76. [76]
  N. Jia, Y. Gao, M. Li, et al., Signal Transduct. Target. Ther. 8 (2023) 280. doi: 10.1038/s41392-023-01499-0
77. [77]
  X. Qiao, Z. Hu, F. Xiong, et al., Lipids Health Dis. 22 (2023) 45.
78. [78]
  Y. Teng, L. Xu, W. Li, et al., Front. Immunol. 14 (2023) 1224443. doi: 10.3389/fimmu.2023.1224443
79. [79]
  N. Jiang, B. Xie, W. Xiao, et al., Nat. Commun. 13 (2022) 1511. doi: 10.1038/s41467-022-29137-3
80. [80]
  N. Caronni, F. La Terza, F.M. Vittoria, et al., Nature 623 (2023) 415–422. doi: 10.1038/s41586-023-06685-2
81. [81]
  M. Ng, D. Cerezo-Wallis, L.G. Ng, A. Hidalgo, Immunity 58 (2025) 40–58. doi: 10.1016/j.immuni.2024.12.009
82. [82]
  J. Zhong, S. Zong, J. Wang, et al., BBA-Mol. Cell Res. 1870 (2023) 119493.
83. [83]
  M.A. Giese, L.E. Hind, A. Huttenlocher, Blood 133 (2019) 2159–2167. doi: 10.1182/blood-2018-11-844548
84. [84]
  Z.G. Fridlender, J. Sun, S. Kim, et al., Cancer Cell 16 (2009) 183–194. doi: 10.1016/j.ccr.2009.06.017
85. [85]
  D. Geh, J. Leslie, R. Rumney, et al., Nat. Rev. Gastroenterol. Hepatol. 19 (2022) 257–273. doi: 10.1038/s41575-021-00568-5
86. [86]
  A.C. Mihaila, L. Ciortan, R.D. Macarie, et al., Front. Immunol. 12 (2021) 708770. doi: 10.3389/fimmu.2021.708770
87. [87]
  C. Tecchio, P. Scapini, G. Pizzolo, M.A. Cassatella, Semin. Cancer Biol. 23 (2013) 159–170. doi: 10.1016/j.semcancer.2013.02.004
88. [88]
  M.T. Palano, M. Gallazzi, M. Cucchiara, et al., Vaccines (Basel) 9 (2021) 1488. doi: 10.3390/vaccines9121488
89. [89]
  S. Xiong, L. Dong, L. Cheng, J. Hematol. Oncol. 14 (2021) 173. doi: 10.1186/s13045-021-01187-y
90. [90]
  M. Laforge, C. Elbim, C. Frère, et al., Nat. Rev. Immunol. 20 (2020) 515–516. doi: 10.1038/s41577-020-0407-1
91. [91]
  Y. Wang, F. Liu, L. Chen, et al., Front. Immunol. 13 (2022) 867516. doi: 10.3389/fimmu.2022.867516
92. [92]
  Y. Zhao, M. Shen, L. Wu, et al., Cell Death Dis. 14 (2023) 587. doi: 10.1038/s41419-023-06110-6
93. [93]
  K.C. Valkenburg, A.E. de Groot, K.J. Pienta, Nat. Rev. Clin. Oncol. 15 (2018) 366–381. doi: 10.1038/s41571-018-0007-1
94. [94]
  R.A. Glabman, P.L. Choyke, N. Sato, Cancers 14 (2022) 3906. doi: 10.3390/cancers14163906
95. [95]
  C.-L. Dai, H.-X. Yang, Q.-P. Liu, et al., Clin. Exp. Med. 23 (2023) 4413–4427. doi: 10.1007/s10238-023-01152-8
96. [96]
  P.C. Tang, A.S. Chan, C.B. Zhang, et al., Front. Med. 8 (2021) 628519. doi: 10.3389/fmed.2021.628519
97. [97]
  M. Song, J. He, Q.Z. Pan, et al., Hepatology 73 (2021) 1717–1735. doi: 10.1002/hep.31792
98. [98]
  R. Sakemura, M. Hefazi, E.L. Siegler, et al., Blood 139 (2022) 3708–3721. doi: 10.1182/blood.2021012811
99. [99]
  L. Bochet, A. Meulle, S. Imbert, et al., Biochem. Biophys. Res. Commun. 411 (2011) 102–106. doi: 10.1016/j.bbrc.2011.06.101
100. [100]
  L.R. Howe, K. Subbaramaiah, C.A. Hudis, A.J. Dannenberg, Clin. Cancer Res. 19 (2013) 6074–6083. doi: 10.1158/1078-0432.CCR-12-2603
101. [101]
  X. Pu, D. Chen, Front. Oncol. 11 (2021) 685923. doi: 10.3389/fonc.2021.685923
102. [102]
  C. Zhang, C. Yue, A. Herrmann, et al., Cell Metab. 31 (2020) 148–161 e145. doi: 10.1016/j.cmet.2019.10.013
103. [103]
  K. Ohashi, J.L. Parker, N. Ouchi, et al., Biol. Chem. 285 (2010) 6153–6160. doi: 10.1074/jbc.M109.088708
104. [104]
  Y. Wang, X. Wang, W.B. Lau, et al., Circ. Res. 114 (2014) 792–805. doi: 10.1161/CIRCRESAHA.114.302439
105. [105]
  R.A. Fontanella, L. Scisciola, M.R. Rizzo, et al., Front. Cardiovasc. Med. 8 (2021) 768026. doi: 10.3389/fcvm.2021.768026
106. [106]
  X. Lian, K. Yang, R. Li, et al., Mol. Cancer 21 (2022) 27. doi: 10.1186/s12943-021-01486-5
107. [107]
  S. Chen, H. Duan, G. Sun, Biomed. Pharmacother. 164 (2023) 114963. doi: 10.1016/j.biopha.2023.114963
108. [108]
  B.D. Chan, W.Y. Wong, M.M. Lee, et al., Proteomics 19 (2019) e1800149. doi: 10.1002/pmic.201800149
109. [109]
  T. Juan, M. Fürthauer, Semin. Cell Dev. Biol. 74 (2018) 66–77. doi: 10.1016/j.semcdb.2017.08.022
110. [110]
  M. Vietri, M. Radulovic, H. Stenmark, Nat. Rev. Mol. Cell Biol. 21 (2020) 25–42. doi: 10.1038/s41580-019-0177-4
111. [111]
  R.L. Williams, S. Urbé, Nat. Rev. Mol. Cell Biol. 8 (2007) 355–368. doi: 10.1038/nrm2162
112. [112]
  Y. Ju, H. Bai, L. Ren, L. Zhang, Int. J. Mol. Sci. 22 (2021) 9060. doi: 10.3390/ijms22169060
113. [113]
  W.M. Henne, N.J. Buchkovich, S.D. Emr, Dev. Cell 21 (2011) 77–91. doi: 10.1016/j.devcel.2011.05.015
114. [114]
  X. Peng, L. Yang, Y. Ma, et al., Cell Commun. Signal 18 (2020) 122. doi: 10.1186/s12964-020-00619-5
115. [115]
  J.V. Fritz, A. Heintz-Buschart, A. Ghosal, et al., Annu. Rev. Nutr. 36 (2016) 301–336. doi: 10.1146/annurev-nutr-071715-050711
116. [116]
  K. O’Brien, K. Breyne, S. Ughetto, et al., Nat. Rev. Mol. Cell Biol. 21 (2020) 585–606. doi: 10.1038/s41580-020-0251-y
117. [117]
  C. Kahlert, R. Kalluri, J. Mol. Med. 91 (2013) 431–437. doi: 10.1007/s00109-013-1020-6
118. [118]
  H. Jiang, H. Zhao, M. Zhang, et al., Front. Immunol. 13 (2022) 824188. doi: 10.3389/fimmu.2022.824188
119. [119]
  W. Guo, T. Qiao, B. Dong, et al., Front. Immunol. 13 (2022) 915985. doi: 10.3389/fimmu.2022.915985
120. [120]
  X. Xia, S. Wang, B. Ni, et al., Oncogene 39 (2020) 6231–6244. doi: 10.1038/s41388-020-01425-6
121. [121]
  J. Lin, X. Wang, S. Zhai, et al., J. Hematol. Oncol. 15 (2022) 128.
122. [122]
  J. Xu, J. Zhang, Z. Zhang, et al., Cell Death Dis. 12 (2021) 373. doi: 10.1109/tit.2020.3033501
123. [123]
  G.K. Panigrahi, P.P. Praharaj, T.C. Peak, et al., Sci. Rep. 8 (2018) 3853. doi: 10.1038/s41598-018-22068-4
124. [124]
  H. Nakamura, K. Takada, Cancer Sci. 112 (2021) 3945–3952. doi: 10.1111/cas.15068
125. [125]
  X. Zhang, S. Yu, X. Li, et al., Pharmacol. Res. 191 (2023) 106777. doi: 10.1016/j.phrs.2023.106777
126. [126]
  W. Zhang, R. Liu, Y. Chen, et al., Oxid. Med. Cell. Longev. 2022 (2022) 3553617. doi: 10.1155/2022/3553617
127. [127]
  Y. Li, W. Zhao, R. Fu, et al., Reprod. Biol. Endocrinol. 20 (2022) 161. doi: 10.1186/s12958-022-01031-z
128. [128]
  S. Gurunathan, M.H. Kang, M. Jeyaraj, J.H. Kim, Int. J. Nanomed. 16 (2021) 2849–2877. doi: 10.2147/ijn.s305269
129. [129]
  S. Gurunathan, J.H. Kim, Int. J. Nanomed. 17 (2022) 5697–5731. doi: 10.2147/ijn.s385113
130. [130]
  S. Gurunathan, M.H. Kang, M. Jeyaraj, J.H. Kim, Int. J. Nanomed. 16 (2021) 515–538. doi: 10.2147/ijn.s291138
131. [131]
  L. Zhu, J. Zang, B. Liu, et al., J. Cell. Physiol. 235 (2020) 7392–7409. doi: 10.1002/jcp.29641
132. [132]
  M. Logozzi, E. Spugnini, D. Mizzoni, et al., Cancer Metast. Rev. 38 (2019) 93–101. doi: 10.1007/s10555-019-09783-8
133. [133]
  Z. Boussadia, J. Lamberti, F. Mattei, et al., J. Exp. Clin. Cancer Res. 37 (2018) 245. doi: 10.1186/s13046-018-0915-z
134. [134]
  C. Gong, X. Zhang, M. Shi, et al., Adv. Sci. 8 (2021) 2002787. doi: 10.1002/advs.202002787
135. [135]
  I. Nakase, N. Ueno, M. Matsuzawa, et al., FEBS Open Bio 11 (2021) 753–767. doi: 10.1002/2211-5463.13107
136. [136]
  K. Yang, M. Fan, X. Wang, et al., Cell Death Differ. 29 (2022) 133–146. doi: 10.1038/s41418-021-00841-9
137. [137]
  X. Cen, S. Liu, K. Cheng, Front. Pharmacol. 9 (2018) 878. doi: 10.3389/fphar.2018.00878
138. [138]
  Y. Liu, Y. Gu, Y. Han, et al., Cancer Cell 30 (2016) 243–256. doi: 10.1016/j.ccell.2016.06.021
139. [139]
  M. Fabbri, A. Paone, F. Calore, et al., Proc. Natl. Acad. Sci. U. S. A. 109 (2012) E2110–E2116.
140. [140]
  X. Li, S. Wang, R. Zhu, et al., J. Hematol. Oncol. 9 (2016) 42. doi: 10.1002/ardp.201500313
141. [141]
  F.H. Khan, M.J. Reza, Y.F. Shao, et al., Biochim. Biophys. Acta Rev. Cancer 1877 (2022) 188776. doi: 10.1016/j.bbcan.2022.188776
142. [142]
  N.P. Bretz, J. Ridinger, A.K. Rupp, et al., Biol. Chem. 288 (2013) 36691–36702. doi: 10.1074/jbc.M113.512806
143. [143]
  A. Chow, W. Zhou, L. Liu, et al., Sci. Rep. 4 (2014) 5750. doi: 10.1038/srep05750
144. [144]
  R. Domenis, A. Cifù, D. Marinò, et al., Sci. Rep. 9 (2019) 8457. doi: 10.1038/s41598-019-44949-y
145. [145]
  H. Xiong, J. Ye, K. Xie, et al., Lipids Health Dis. 21 (2022) 147. doi: 10.1186/s12944-022-01755-2
146. [146]
  X. Wang, Z. Xiang, G.S.W. Tsao, W. Tu, Cell. Mol. Immunol. 18 (2021) 501–503. doi: 10.1038/s41423-020-0420-0
147. [147]
  F. Li, L. Zhan, Q. Dong, et al., OncoTargets Ther. 13 (2020) 7851–7864. doi: 10.2147/ott.s253485
148. [148]
  A. Shang, C. Gu, C. Zhou, et al., Cell Commun. Signal. 18 (2020) 52. doi: 10.1186/s12964-020-0517-1
149. [149]
  M. Zhou, X. He, C. Mei, C. Ou, Biomark. Res. 11 (2023) 100. doi: 10.1186/s40364-023-00538-w
150. [150]
  N. Zheng, T. Wang, Q. Luo, et al., Oncoimmunology 12 (2023) 2210959. doi: 10.1080/2162402X.2023.2210959
151. [151]
  C. Cianciaruso, T. Beltraminelli, F. Duval, et al., Cell Rep. 27 (2019) 3062–3080 e3011. doi: 10.1016/j.celrep.2019.05.008
152. [152]
  J. Lan, L. Sun, F. Xu, et al., Cancer Res. 79 (2019) 146–158. doi: 10.1158/0008-5472.can-18-0014
153. [153]
  Y. Yang, Z. Guo, W. Chen, et al., Mol. Ther. 29 (2021) 1226–1238. doi: 10.1016/j.ymthe.2020.11.024
154. [154]
  L. Wang, Y. Shan, S. Zheng, et al., Stem Cells Int. 2023 (2023) 2759679.
155. [155]
  A. Tyagi, S.Y. Wu, S. Sharma, et al., Oncogene 41 (2022) 3079–3092. doi: 10.1038/s41388-022-02322-w
156. [156]
  D.S. Rubenich, N. Omizzollo, M.J. Szczepański, et al., Cytokine Growth Factor Rev. 61 (2021) 16–26. doi: 10.1016/j.cytogfr.2021.08.002
157. [157]
  B. Ou, Y. Liu, Z. Gao, et al., Cell Death Dis. 13 (2022) 905. doi: 10.3390/molecules27030905
158. [158]
  W.J. Yeoh, V.P. Vu, P. Krebs, Cytokine 157 (2022) 155961. doi: 10.1016/j.cyto.2022.155961
159. [159]
  C. Feng, L. Kou, P. Yin, Y. Jing, Oncol. Lett. 23 (2022) 158. doi: 10.3892/ol.2022.13278
160. [160]
  X. Zhang, B. Sai, F. Wang, et al., Mol. Cancer 18 (2019) 40. doi: 10.1186/s12943-019-0959-5
161. [161]
  H. Zhang, T. Deng, R. Liu, et al., Mol. Cancer 19 (2020) 43. doi: 10.1186/s12943-020-01168-8
162. [162]
  K.E. Richards, A.E. Zeleniak, M.L. Fishel, et al., Oncogene 36 (2017) 1770–1778. doi: 10.1038/onc.2016.353
163. [163]
  Z. Wang, J. He, D.H. Bach, et al., J. Exp. Clin. Cancer Res. 41 (2022) 4. doi: 10.1186/s13046-021-02209-w
164. [164]
  I. Lazar, E. Clement, S. Dauvillier, et al., Cancer Res. 76 (2016) 4051–4057.
165. [165]
  Y. Pan, X. Hui, R.L.C. Hoo, et al., J. Clin. Invest. 129 (2019) 834–849. doi: 10.1172/jci123069
166. [166]
  X. Zhang, L. Chen, B. Xiao, et al., Biochem. Biophys. Res. Commun. 511 (2019) 551–558. doi: 10.1016/j.bbrc.2019.02.082
167. [167]
  M. Wei, X. Gao, L. Liu, et al., ACS Nano 14 (2020) 5099–5110. doi: 10.1021/acsnano.0c01860
168. [168]
  L.A. Martin, J.E. Head, S. Pancholi, et al., Mol. Cancer Ther. 6 (2007) 2458–2467. doi: 10.1158/1535-7163.MCT-06-0452
169. [169]
  P. Haluska, G.K. Dy, A.A. Adjei, Eur. J. Cancer 38 (2002) 1685–1700. doi: 10.1016/S0959-8049(02)00166-1
170. [170]
  A. Datta, H. Kim, L. McGee, et al., Sci. Rep. 8 (2018) 8161. doi: 10.1038/s41598-018-26411-7
171. [171]
  J.L. Johnson, M. Ramadass, J. He, et al., Biol. Chem. 291 (2016) 25965–25982. doi: 10.1074/jbc.M116.741884
172. [172]
  T. Lallemand, M. Rouahi, A. Swiader, et al., Arterioscl. Throm. Vas. 38 (2018) 1479–1492. doi: 10.1161/atvbaha.118.311208
173. [173]
  A. Datta, H. Kim, M. Lal, et al., Cancer Lett. 408 (2017) 73–81. doi: 10.1016/j.canlet.2017.08.020
174. [174]
  J. Li, K. Liu, Y. Liu, et al., Nat. Immunol. 14 (2013) 793–803. doi: 10.1038/ni.2647
175. [175]
  A. Takahashi, R. Okada, K. Nagao, et al., Nat. Commun. 8 (2017) 15287. doi: 10.1038/ncomms15287
176. [176]
  M. Ho, T. Chen, J. Liu, et al., Leukemia 34 (2020) 196–209. doi: 10.1038/s41375-019-0493-x
177. [177]
  T.H. Wu, C.H. Wu, C.J. Huang, Y.C. Chang, Langmuir 37 (2021) 3399–3409. doi: 10.1021/acs.langmuir.0c03613
178. [178]
  M. Tayebi, Y. Zhou, P. Tripathi, et al., Anal. Chem. 92 (2020) 10733–10742. doi: 10.1021/acs.analchem.0c02006
179. [179]
  X. Xie, H. Nie, Y. Zhou, et al., Nat. Commun. 10 (2019) 5476. doi: 10.1038/s41467-019-13316-w
180. [180]
  J. Chen, R. Xu, J. Xia, et al., Pathol. Res. Pract. 215 (2019) 152379. doi: 10.1016/j.prp.2019.03.008
181. [181]
  L. Zheng, Y. Ding, S. Fang, et al., ACS Nano 18 (2024) 27597–27616. doi: 10.1021/acsnano.4c08690
182. [182]
  S.K. Lee, C.M. Han, W. Park, et al., Mat. Sci. Eng. C: Mater. 94 (2019) 65–75. doi: 10.1016/j.msec.2018.09.011
183. [183]
  L. Zhang, Y. Jia, J. Yang, et al., ACS Nano 16 (2022) 12036–12048. doi: 10.1021/acsnano.2c02183
184. [184]
  J.S. Miller, L.L. Lanier, Cancer Lett. 3 (2019) 77–103. doi: 10.1146/annurev-cancerbio-030518-055653
185. [185]
  C. Federici, E. Shahaj, S. Cecchetti, et al., Front. Immunol. 11 (2020) 262. doi: 10.3389/fimmu.2020.00262
186. [186]
  A. Shoae-Hassani, A.A. Hamidieh, M. Behfar, et al., J. Immunother. 40 (2017) 265–276. doi: 10.1097/CJI.0000000000000179
187. [187]
  M. Zhang, W. Shao, T. Yang, et al., Adv. Sci. 9 (2022) e2201135. doi: 10.1002/advs.202201135
188. [188]
  C.H. Wu, J. Li, L. Li, et al., J. Extracell. Vesicles 8 (2019) 1588538. doi: 10.1080/20013078.2019.1588538
189. [189]
  P. Neviani, P.M. Wise, M. Murtadha, et al., Cancer Res. 79 (2019) 1151–1164. doi: 10.1158/0008-5472.can-18-0779
190. [190]
  Y. Zheng, X. Zou, Q. Li, et al., Saudi. Pharm. J. 33 (2025) 8. doi: 10.1007/s44446-025-00009-3
191. [191]
  H. Kim, H.-J. Park, H.W. Chang, et al., Bioact. Mater. 25 (2023) 527–540.
192. [192]
  Y. Zheng, Y. Han, Q. Sun, Z. Li, Exploration 2 (2022) 20210166. doi: 10.1002/EXP.20210166
193. [193]
  P. Wang, H. Wang, Q. Huang, et al., Theranostics 9 (2019) 1714–1727. doi: 10.7150/thno.30716
194. [194]
  X. Dai, Y. Ye, F. He, Front. Immunol. 13 (2022) 865245. doi: 10.3389/fimmu.2022.865245
195. [195]
  L. Cheng, Y. Wang, L. Huang, Mol. Ther. 25 (2017) 1665–1675. doi: 10.1016/j.ymthe.2017.02.007
196. [196]
  Y. Li, Z. Cai, Z. Wang, et al., Chin. Chem. Lett. 36 (2025) 109942. doi: 10.1016/j.cclet.2024.109942
197. [197]
  Y. Wang, Y. Xiang, V.W. Xin, et al., J. Hematol. Oncol. 13 (2020) 107. doi: 10.1186/s13045-020-00939-6
198. [198]
  A. Del Prete, V. Salvi, A. Soriani, et al., Cell. Mol. Immunol. 20 (2023) 432–447. doi: 10.1038/s41423-023-00990-6
199. [199]
  A. Hazrati, S. Soudi, K. Malekpour, et al., Biomark. Res. 10 (2022) 30. doi: 10.1186/s40364-022-00374-4
200. [200]
  G. Tuluwengjiang, I. Rasulova, S. Ahmed, et al., Pathol. Res. Pract. 254 (2024) 155097. doi: 10.1016/j.prp.2024.155097
201. [201]
  J. Xia, Y. Miao, X. Wang, et al., Biomed. Pharmacother. 152 (2022) 113250. doi: 10.1016/j.biopha.2022.113250
202. [202]
  L. Chen, J. Zhang, Y. Huang, et al., Pharmaceutics 17 (2025) 326. doi: 10.3390/pharmaceutics17030326
203. [203]
  L. Zitvogel, A. Regnault, A. Lozier, et al., Nat. Med. 4 (1998) 594–600. doi: 10.1038/nm0598-594
204. [204]
  Y. Yao, L. Chen, W. Wei, et al., Biochem. Biophys. Res. Commun. 436 (2013) 60–65. doi: 10.1016/j.bbrc.2013.05.058
205. [205]
  T. Li, X. Li, G. Han, et al., Pharmaceutics 15 (2022) 21. doi: 10.3390/pharmaceutics15010021
206. [206]
  L. Zheng, B. Hu, D. Zhao, et al., Chin. Chem. Lett. 35 (2024) 108647. doi: 10.1016/j.cclet.2023.108647
207. [207]
  Y. Ding, Y. Wang, Q. Hu, Exploration 2 (2022) 20210106. doi: 10.1002/EXP.20210106
208. [208]
  R.O. Elliott, M. He, Pharmaceutics 13 (2021) 122. doi: 10.3390/pharmaceutics13010122
209. [209]
  J. Yang, Y. Li, S. Jiang, et al., Exploration 5 (2025) 20240039. doi: 10.1002/EXP.20240039
210. [210]
  M.A. Di Bella, Biology 11 (2022) 804. doi: 10.3390/biology11060804
211. [211]
  T. Wang, Y. Fu, S. Sun, et al., Chin. Chem. Lett. 34 (2023) 107508. doi: 10.1016/j.cclet.2022.05.022
212. [212]
  M. Cully, Nat. Rev. Drug Discov. 20 (2021) 6–7. doi: 10.1038/d41573-020-00220-y
213. [213]
  A. Srivastava, S. Rathore, A. Munshi, R. Ramesh, Semin. Cancer Biol. 86 (2022) 80–100. doi: 10.1016/j.semcancer.2022.02.020
214. [214]
  P.S. Rawat, A. Jaiswal, A. Khurana, et al., Biomed. Pharmacother. 139 (2021) 111708. doi: 10.1016/j.biopha.2021.111708
215. [215]
  X. Xie, S. Lian, Y. Zhou, et al., J. Control. Release 331 (2021) 404–415. doi: 10.1016/j.jconrel.2021.01.030
216. [216]
  M. Hadla, S. Palazzolo, G. Corona, et al., Nanomedicine 11 (2016) 2431–2441. doi: 10.2217/nnm-2016-0154
217. [217]
  J. Wang, W. Tang, M. Yang, et al., Biomaterials 273 (2021) 120784. doi: 10.1016/j.biomaterials.2021.120784
218. [218]
  R. Tian, Z. Wang, R. Niu, et al., Front. Bioeng. Biotechnol. 8 (2020) 1010. doi: 10.3389/fbioe.2020.01010
219. [219]
  F. Liu, F. Meng, Z. Yang, et al., Chin. Chem. Lett. 35 (2024) 109335. doi: 10.1016/j.cclet.2023.109335
220. [220]
  M. Arabpour, A. Saghazadeh, N. Rezaei, Int. Immunopharmacol. 97 (2021) 107823. doi: 10.1016/j.intimp.2021.107823
221. [221]
  M. Yousefi Dehbidi, N. Goodarzi, M.H. Azhdari, M. Doroudian, Rev. Med. Virol. 32 (2022) e2281. doi: 10.1002/rmv.2281
222. [222]
  A.M. Kirkham, A.J.M. Bailey, M. Monaghan, et al., Stem Cells Transl. Med. 11 (2022) 675–687. doi: 10.1093/stcltm/szac038
223. [223]
  Y. Li, Y.-N. Wang, Y.-G. Luo, et al., Chin. Chem. Lett. 35 (2024) 109576. doi: 10.1016/j.cclet.2024.109576
224. [224]
  L. Xi, L. Wang, M. Zhang, et al., ACS Biomater. Sci. Eng. 9 (2023) 5843–5854. doi: 10.1021/acsbiomaterials.2c01257
225. [225]
  H.I. Tsai, Y. Wu, X. Liu, et al., Adv. Sci. 9 (2022) e2102634. doi: 10.1002/advs.202102634
226. [226]
  C. He, M. Zhang, L. Liu, et al., Acta Biomater. 143 (2022) 406–417. doi: 10.1016/j.actbio.2022.02.028
227. [227]
  S. Chen, S. Li, H. Wang, Oncol. Transl. Med. 10 (2024) 281–285. doi: 10.1097/ot9.0000000000000063
228. [228]
  Y. Wu, H. Song, H. Shi, G. Wang, Oncol. Transl. Med. 11 (2025) 5–9. doi: 10.1097/ot9.0000000000000069
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2. [2]
  Fengjie Liu , Fansu Meng , Zhenjiang Yang , Huan Wang , Yuehong Ren , Yu Cai , Xingwang Zhang . Exosome-biomimetic nanocarriers for oral drug delivery. Chinese Chemical Letters, 2024, 35(9): 109335-. doi: 10.1016/j.cclet.2023.109335
3. [3]
  Jingwen Zhao , Jianpu Tang , Zhen Cui , Limin Liu , Dayong Yang , Chi Yao . A DNA micro-complex containing polyaptamer for exosome separation and wound healing. Chinese Chemical Letters, 2024, 35(9): 109303-. doi: 10.1016/j.cclet.2023.109303
4. [4]
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5. [5]
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6. [6]
  Chanqi Ye , Jia Zhang , Jie Shen , Ruyin Chen , Qiong Li , Peng Zhao , Dong Chen , Jian Ruan . Attractive Pickering emulsion gel loaded with oxaliplatin and lactate dehydrogenase inhibitor increases the anti-tumor effect in hepatocellular carcinoma. Chinese Chemical Letters, 2025, 36(7): 110519-. doi: 10.1016/j.cclet.2024.110519
7. [7]
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8. [8]
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9. [9]
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11. [11]
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12. [12]
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13. [13]
  Qianyun Ye , Yuanyuan Liang , Yuhe Yuan , Xiaohuan Sun , Liqi Zhu , Xuan Wu , Jie Han , Rong Guo . pH-responsive chiral supramolecular cysteine-Zn²⁺-indocyanine green assemblies for triple-level chirality-specific anti-tumor efficacy. Chinese Chemical Letters, 2025, 36(5): 110432-. doi: 10.1016/j.cclet.2024.110432
14. [14]
  Fengyun Li , Zerong Pei , Shuting Chen , Gen li , Mengyang Liu , Liqin Ding , Jingbo Liu , Feng Qiu . Multifunctional nano-herb based on tumor microenvironment for enhanced tumor therapy of gambogic acid. Chinese Chemical Letters, 2024, 35(5): 108752-. doi: 10.1016/j.cclet.2023.108752
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16. [16]
  Yi Cao , Xiaojiao Ge , Yuanyuan Wei , Lulu He , Aiguo Wu , Juan Li . Tumor microenvironment-activatable neuropeptide-drug conjugates enhanced tumor penetration and inhibition via multiple delivery pathways and calcium deposition. Chinese Chemical Letters, 2024, 35(4): 108672-. doi: 10.1016/j.cclet.2023.108672
17. [17]
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19. [19]
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20. [20]
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