Citation: Shuairu Wang, Dongsheng Lian, Chuyang Sun, Minghao Xu, Mingming Zhu, Chenxu Yan, Zhiqian Guo. High selective NIR-Ⅱ fluorescent probe for sensing phosgene in plants[J]. Chinese Chemical Letters, ;2026, 37(7): 111744. doi: 10.1016/j.cclet.2025.111744 shu

High selective NIR-Ⅱ fluorescent probe for sensing phosgene in plants

Shuairu Wang ^a ,
Dongsheng Lian ^a ,
Chuyang Sun ^a ,
Minghao Xu ^a ,
Mingming Zhu ^{b, *,} ,
Chenxu Yan ^a ,
Zhiqian Guo ^{a, c, *,}

a.
Key Laboratory for Advanced Materials and Joint International Research Laboratory of Precision Chemistry and Molecular Engineering, Feringa Nobel Prize Scientist Joint Research Center, Institute of Fine Chemicals, Frontiers Science Center for Materiobiology and Dynamic Chemistry, School of Chemistry and Molecular Engineering, East China University of Science and Technology, Shanghai 200237, China
b.
Division of Gastroenterology and Hepatology, NHC Key Laboratory of Digestive Diseases, Shanghai Institute of Digestive Disease, Inflammatory Bowel Disease Research Center, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200001, China
c.
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China

gzqzmm@163.com

guozq@ecust.edu.cn

Received Date: 2 July 2025
Revised Date: 18 August 2025
Accepted Date: 19 August 2025
Available Online: 20 August 2025

Figures(5)

Phosgene, a highly toxic chemical warfare agent and industrial hazard, poses significant environmental and health risks, necessitating the development of rapid and reliable detection methods. Herein, we present a novel near infrared Ⅱ (NIR-Ⅱ) fluorescent probe based on silicon rhodamine and an o-phenylenediamine-responsive group for the sensitive and selective detection of phosgene. In the presence of phosgene, it generates a distinct color change and lights up NIR-Ⅱ (900 nm) emission, enabling both naked-eye visualization and fluorescence in vivo analysis. The probe shows rapid exceptional selectivity for phosgene and achieves rapid detection in solutions, gases, and soils. Notably, we successfully utilize this probe for in vivo imaging in Arabidopsis thaliana, enabling high signal-to-noise ratio real-time monitoring of phosgene within plant systems with minimal interference from autofluorescence. This work advances the design of reaction-based NIR-Ⅱ probes for hazardous chemical monitoring, combining simple operation, high sensitivity, and broad applicability, thereby contributing to environmental safety and sustainability.
- NIR-Ⅱ emission,
- Fluorescent probe,
- Soil analysis,
- Plant imaging,
- Phosgene
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