Citation: Lei Wang, Jianing Zhang, Jin Xiong, Wenbo Dai, Miaochang Liu, Xiaobo Huang, Yuye Chai, Yunxiang Lei, Zhengxu Cai, Minyu Zhu. Enhancing the phosphorescence performance of organic doped system by carbonylation of guests[J]. Chinese Chemical Letters, ;2026, 37(5): 111706. doi: 10.1016/j.cclet.2025.111706 shu

Enhancing the phosphorescence performance of organic doped system by carbonylation of guests

Lei Wang ^a ,
Jianing Zhang ^a ,
Jin Xiong ^a ,
Wenbo Dai ^{a, c} ,
Miaochang Liu ^a ,
Xiaobo Huang ^a ,
Yuye Chai ^{a, *,} ,
Yunxiang Lei ^{a, c, *,} ,
Zhengxu Cai ^d ,
Minyu Zhu ^{b, *,}

a.
School of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325000, China
b.
Department of Orthopedics (Spine Surgery), First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China
c.
Key Lab of Biohealth Materials and Chemistry of Wenzhou, Wenzhou 325035, China
d.
Beijing Key Laboratory of Construction Tailorable Advanced Functional Materials and Green Applications, School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081, China

cyy@wzu.edu.cn

yunxianglei@wzu.edu.cn

zhuminyu@wzhospital.cn

Received Date: 12 May 2025
Revised Date: 9 August 2025
Accepted Date: 10 August 2025
Available Online: 11 August 2025

Figures(6)

The host-guest doped strategy has become the main method for constructing organic phosphorescence materials. In the doped system, guest molecules emit phosphorescence, therefore, improving the luminescence performance of guests is the key to optimizing the phosphorescence property of the doped materials. Herein, we designed to introduce the carbonyl group on the guest molecules. Carbonyl group can effectively promote n-π^* transitions, thereby increasing the spin-orbit coupling (SOC) constant of the guests, ultimately improving the phosphorescence performance of the doped materials. Using the indazole derivative (IZ) as the initial guest, two other guests containing carboxyl group (IZ-CG) or ethoxycarbonyl group (IZ-EG) were successfully obtained. Further selected two small molecules and two polymers as the hosts to construct four doped systems. Among these doped systems, the phosphorescence performance of doped materials with IZ-CG or IZ-EG as the guest is significantly better than that of doped materials with IZ as the guest. The phosphorescence lifetime has increased by 2.3-5.0 times, and the phosphorescence quantum yield has increased by 3.0-5.7 times. Theoretical calculations and single crystal structures indicated that carbonyl groups can not only increase the SOC constant, but also enhance the intermolecular interactions of the guests. In addition, doped material can be effectively used for imaging subcutaneous and lymph nodes in mice, achieving a high signal-to-noise ratio.
- Room temperature phosphorescence,
- Host-guest doped system,
- Carbonyl induced emission,
- Hydrogen bonds,
- Bioimaging
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