Citation: Kuanhong Cao, Sainan Chu, Yuanhua Ding, Shanming Lu, Lei Yu, Juan Du. Sustainable Se/C catalysts from carbohydrates: Unlocking oxidative deoximation reaction with high turnover numbers via free radical mechanisms[J]. Chinese Chemical Letters, ;2026, 37(1): 111486. doi: 10.1016/j.cclet.2025.111486 shu

Sustainable Se/C catalysts from carbohydrates: Unlocking oxidative deoximation reaction with high turnover numbers via free radical mechanisms

Kuanhong Cao ^{a, b} ,
Sainan Chu ^c ,
Yuanhua Ding ^c ,
Shanming Lu ^{a, *,} ,
Lei Yu ^{c, *,} ,
Juan Du ^{b, *,}

a.
Department of Pathology, Longgang Central Hospital, Shenzhen 518116, China
b.
Ciechanover Institute of Precision and Regenerative Medicine, School of Medicine, The Chinese University of Hong Kong, Shenzhen 518172, China
c.
School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou 225009, China

lushanming@163.com

yulei@yzu.edu.cn

dujuan@cuhk.edu.cn

Received Date: 25 March 2025
Revised Date: 5 June 2025
Accepted Date: 17 June 2025
Available Online: 18 June 2025

Figures(5)

By using carbohydrates as the biomass carbon sources, Se/C materials could be easily prepared. The materials could catalyze the oxidative deoximation reactions, which are significant transformations in both pharmaceutical industry and fine chemical production. Compared with the reported organoselenium-catalyzed ionic reactions, the Se/C-catalyzed deoximation reactions occurred via unique free radical mechanisms, endowing the Se species high catalytic reactivity. The Se/C catalysts were recyclable and their turnover numbers (TONs) were high (>10⁴), making the reactions practical for industrial grade preparation. The unique free radical mechanisms of the reaction and green and practical features of the catalysts are the characteristics and advantages of the work.
- Selenium,
- Carbon,
- Biomass,
- Deoximation,
- Oxidation
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