Citation: Jiarong Li, Shude Liu, Yuanzhao Xie, Yue Sun, Zhuyu Liu, Meihua Chen, Yaobang Li, Yonghui Deng. Nanoemulsion-assisted assembly and polymerization towards core-shell magnetic mesoporous melamine-formaldehyde resin microspheres[J]. Chinese Chemical Letters, ;2026, 37(4): 111433. doi: 10.1016/j.cclet.2025.111433 shu

Nanoemulsion-assisted assembly and polymerization towards core-shell magnetic mesoporous melamine-formaldehyde resin microspheres

Jiarong Li ^a ,
Shude Liu ^a ,
Yuanzhao Xie ^a ,
Yue Sun ^a ,
Zhuyu Liu ^a ,
Meihua Chen ^{a, *,} ,
Yaobang Li ^{b, *,} ,
Yonghui Deng ^{a, *,}

a.
Department of Chemistry, Shanghai Stomatological Hospital & School of Stomatology, State Key Laboratory of Coatings for Advanced Equipment, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, College of Smart Materials and Future Energy, Fudan University, Shanghai 200433, China
b.
Zhejiang Fulai New Materials, Co., Ltd., Jiaxing 314103, China

chenmeihua@fudan.edu.cn

yaobangli@alleadprint.com

yhdeng@fudan.edu.cn

Received Date: 27 April 2025
Revised Date: 3 June 2025
Accepted Date: 10 June 2025
Available Online: 10 June 2025

Figures(5)

Core-shell magnetic polymer microspheres with mesoporous organic shells hold immense potential in diverse applications, encompassing adsorption, separation, delivery/immobilization of guest molecules in catalysis and controlled drug release. Herein, magnetic mesoporous melamine-formaldehyde resin microspheres (Fe₃O₄@SiO₂@mMF) are constructed via a nanoemulsion-assisted interfacial co-assembly and polymerization strategy, using Pluronic F127 as a template agent and soluble melamine-formaldehyde (MF) oligomer as the precursor. The resulting microspheres possess radially oriented mesopores, superparamagnetic properties, and abundant N-containing active sites (nitrogen content: 15.02 wt%). The as-synthesized Fe₃O₄@SiO₂@mMF microspheres as ideal catalyst supports, exhibit exceptional loading capacity for phosphotungstic acid (PTA). The as-formed Fe₃O₄@SiO₂@mMF/PTA composites demonstrate not only good catalytic performance in the esterification reaction of n-butanol and acetic acid with a high conversion of 92% (to acetic acid) but also excellent antimicrobial performance against Staphylococcus aureus and Escherichia coli with viabilities of 11.58% and 7.35%, respectively.
- Core-shell structure,
- Magnetic mesoporous materials,
- Melamine-formaldehyde resin,
- Esterification catalysis,
- Antibacterial materials
1. [1]
  J. Liu, X. Chen, K. Chen, et al., Science 383 (2024) 1198–1204. doi: 10.1126/science.adk9089
2. [2]
  E.J.W. Crossland, N. Noel, V. Sivaram, et al., Nature 495 (2013) 215–219. doi: 10.1038/nature11936
3. [3]
  W. Xie, X. Huang, C. Zhu, et al., Adv. Mater. 36 (2024) 2313920. doi: 10.1002/adma.202313920
4. [4]
  Q. Yuan, A.X. Yin, C. Luo, et al., J. Am. Chem. Soc. 130 (2008) 3465–3472. doi: 10.1021/ja0764308
5. [5]
  Y. Liang, X. Yang, X. Wang, et al., Nat. Commun. 14 (2023) 5223. doi: 10.1038/s41467-023-40973-9
6. [6]
  Y. Kang, S. Li, O. Cretu, et al., Sci. Adv. 10 (2024) eado2442. doi: 10.1126/sciadv.ado2442
7. [7]
  M. Eguílaz, R. Villalonga, G. Rivas, Biosens. Bioelectron. 111 (2018) 144–151. doi: 10.1016/j.bios.2018.04.004
8. [8]
  Z. Tang, X. Li, L. Tong, et al., Angew. Chem. Int. Ed. 133 (2021) 23800–23805. doi: 10.1002/ange.202110351
9. [9]
  F. Jiang, Y. Deng, K. Chen, et al., Adv. Mater. 36 (2024) 2313547. doi: 10.1002/adma.202313547
10. [10]
  Y. Ren, Y. Deng, Z. Wang, et al., Small 20 (2024) 2311659. doi: 10.1002/smll.202311659
11. [11]
  T. Zhao, L. Chen, M. Liu, et al., Nat. Chem. 15 (2023) 832–840. doi: 10.1038/s41557-023-01183-4
12. [12]
  X. Hong, X. Zhong, G. Du, et al., Sci. Adv. 6 (2020) eaaz4462. doi: 10.1126/sciadv.aaz4462
13. [13]
  S. Liu, J. Li, Y. Zou, et al., Small 19 (2023) 2304631. doi: 10.1002/smll.202304631
14. [14]
  X. Huang, J. Gao, Y. Qin, et al., ACS Nano 18 (2024) 21459–21471. doi: 10.1021/acsnano.4c06200
15. [15]
  G.O. Park, J. Yoon, S.B. Park, et al., Small 14 (2018) 1702985. doi: 10.1002/smll.201702985
16. [16]
  J. Liu, T. Yang, D.W. Wang, et al., Nat. Commun. 4 (2013) 2798. doi: 10.1038/ncomms3798
17. [17]
  T. Zhao, X. Zhang, R. Lin, et al., J. Am. Chem. Soc. 142 (2020) 20359–20367. doi: 10.1021/jacs.0c08277
18. [18]
  Y. Li, B.P. Bastakoti, M. Imura, et al., Chem. Eur. J. 21 (2015) 6375–6380. doi: 10.1002/chem.201406137
19. [19]
  D. Niu, Z. Liu, Y. Li, et al., Adv. Mater. 26 (2014) 4947–4953. doi: 10.1002/adma.201400815
20. [20]
  D. Shen, J. Yang, X. Li, et al., Nano Lett. 14 (2014) 923–932. doi: 10.1021/nl404316v
21. [21]
  Z. Teng, S. Wang, X. Su, et al., Adv. Mater. 26 (2014) 3741–3747. doi: 10.1002/adma.201400136
22. [22]
  S. Kerkhofs, T. Willhammar, H. Van Den Noortgate, et al., Chem. Mater. 27 (2015) 5161–5169. doi: 10.1021/acs.chemmater.5b01772
23. [23]
  Y. Meng, D. Gu, F. Zhang, et al., Chem. Mater. 18 (2006) 4447–4464. doi: 10.1021/cm060921u
24. [24]
  F. Wei, T. Zhang, R. Dong, et al., Nat. Protoc. 18 (2023) 2459–2484. doi: 10.1038/s41596-023-00845-4
25. [25]
  L. Peng, H. Peng, W. Li, et al., Nat. Protoc. 18 (2023) 1155–1178. doi: 10.1038/s41596-022-00784-6
26. [26]
  P. Zhang, L. Wang, S. Yang, et al., Nat. Commun. 8 (2017) 15020. doi: 10.1038/ncomms15020
27. [27]
  X. Yang, P. Lu, L. Yu, et al., Adv. Funct. Mater. 30 (2020) 2002488. doi: 10.1002/adfm.202002488
28. [28]
  R. Mo, F. Li, X. Tan, et al., Nat. Commun. 10 (2019) 1474. doi: 10.1038/s41467-019-09274-y
29. [29]
  C. Cui, W. Qian, Y. Yu, et al., J. Am. Chem. Soc. 136 (2014) 2256–2259. doi: 10.1021/ja412219r
30. [30]
  S.T. Lim, J.H. Kim, C.Y. Lee, et al., Sci. Rep. 9 (2019) 10922. doi: 10.1038/s41598-019-47100-z
31. [31]
  X. Zhu, Y. Xia, X. Zhang, et al., J. Mater. Chem. A 7 (2019) 8975–8983. doi: 10.1039/c9ta01478k
32. [32]
  P. Liu, Y. Li, C. Sun, et al., ACS Appl. Nano Mater. 8 (2025) 7267–7277. doi: 10.1021/acsanm.5c00621
33. [33]
  M. Lei, M. Gao, X. Yang, et al., ACS Appl. Mater. Interfaces 13 (2021) 51933–51944. doi: 10.1021/acsami.1c07322
34. [34]
  J. Ma, Y. Li, X. Zhou, et al., Small 16 (2020) 2004772. doi: 10.1002/smll.202004772
35. [35]
  F. Ma, Y. Yang, G. Jiao, et al., RSC Adv. 14 (2024) 25227–25234. doi: 10.1039/d4ra03690e
36. [36]
  J. Liu, M. Zheng, X. Shi, et al., Adv. Funct. Mater. 26 (2016) 919–930. doi: 10.1002/adfm.201504019
37. [37]
  D. Wang, T. Xie, Q. Peng, et al., J. Am. Chem. Soc. 130 (2008) 4016–4022. doi: 10.1021/ja710004h
38. [38]
  H. Huang, S. Yin, Z. Fu, et al., J. Mater. Chem. C 18 (2025) 9106–9114. doi: 10.1039/d4tc05441e
39. [39]
  J. Kim, H.S. Kim, N. Lee, et al., Angew. Chem. Int. Ed. 47 (2008) 8438–8441. doi: 10.1002/anie.200802469
40. [40]
  Y. Deng, D. Qi, C. Deng, et al., J. Am. Chem. Soc. 130 (2008) 28–29. doi: 10.1021/ja0777584
41. [41]
  Y. Deng, Y. Cai, Z. Sun, et al., J. Am. Chem. Soc. 132 (2010) 8466–8473. doi: 10.1021/ja1025744
42. [42]
  H. Yi, Y.F. Zhao, Y. -T. Chan, et al., Science 383 (2024) 634–639. doi: 10.1126/science.adk1270
43. [43]
  M. Urso, M. Ussia, X. Peng, et al., Nat. Commun. 14 (2023) 6969. doi: 10.1038/s41467-023-42674-9
44. [44]
  Y. Zou, Z. Sun, Q. Wang, et al., Chem. Rev. 125 (2025) 972–1048. doi: 10.1021/acs.chemrev.4c00710
45. [45]
  Z. Zhang, P. He, W. Ma, et al., Adv. Funct. Mater. 33 (2023) 2302212. doi: 10.1002/adfm.202302212
46. [46]
  Q. Yue, J. Li, Y. Zhang, et al., J. Am. Chem. Soc. 139 (2017) 15486–15493. doi: 10.1021/jacs.7b09055
47. [47]
  Y. Zhang, Q. Yue, L. Yu, et al., Adv. Mater. 30 (2018) 1800345. doi: 10.1002/adma.201800345
48. [48]
  J. Zhang, W. Sun, L. Bergman, et al., Mater. Lett. 67 (2012) 379–382. doi: 10.1016/j.matlet.2011.09.086
49. [49]
  R. de Andrade, R. d. C. d. R. Schmidt, L.S. Gomes, et al., Pharmaceutics 16 (2024) 357. doi: 10.3390/pharmaceutics16030357
50. [50]
  Y. Zhang, Q. Yue, M.M. Zagho, et al., ACS Appl. Mater. Interfaces 11 (2019) 10356–10363. doi: 10.1021/acsami.8b18721
51. [51]
  P. Pan, Q. Yue, X. Yang, et al., Small 17 (2021) 2006925. doi: 10.1002/smll.202006925
52. [52]
  H. He, S. Ye, W. Zhang, et al., Chem. Eng. J. 489 (2024) 151294. doi: 10.1016/j.cej.2024.151294
53. [53]
  J. Li, S. Liu, Y. Xie, et al., J. Mater. Chem. A 12 (2024) 22627–22636. doi: 10.1039/d4ta04277h
54. [54]
  Y. Liu, S. Wu, W. Xiong, et al., Adv. Mater. Interfaces 10 (2023) 2201631. doi: 10.1002/admi.202201631
55. [55]
  D. Wu, J. Zhou, X. Chen, et al., Biomaterials 238 (2020) 119847. doi: 10.1016/j.biomaterials.2020.119847
56. [56]
  S. Gao, Z. Wang, L. Ma, et al., ACS Catal. 10 (2020) 1375–1380. doi: 10.1021/acscatal.9b04877
57. [57]
  Z. Xiao, W. Zuo, L. Chen, et al., ACS Appl. Mater. Interfaces 13 (2021) 43925–43936. doi: 10.1021/acsami.1c10341
58. [58]
  J. Liu, Z. Sun, Y. Deng, et al., Angew. Chem. Int. Ed. 48 (2009) 5875–5879. doi: 10.1002/anie.200901566
59. [59]
  H.L. Ding, Y.X. Zhang, S. Wang, et al., Chem. Mater. 24 (2012) 4572–4580. doi: 10.1021/cm302828d
60. [60]
  I.D. Ivanchikova, N.V. Maksimchuk, R.I. Maksimovskaya, et al., ACS Catal. 4 (2014) 2706–2713. doi: 10.1021/cs500738e
61. [61]
  L. Hombach, N. Hausen, A.G. Manjón, et al., Appl. Catal. A: Gen. 666 (2023) 119392. doi: 10.1016/j.apcata.2023.119392
62. [62]
  X.Y. Xue, Y. Sun, Q.W. Sun, et al., Sustain. Energy Fuels 8 (2024) 1295–1303. doi: 10.1039/d3se01720f
63. [63]
  N.I. Gumerova, A. Rompel, Nat. Rev. Chem. 2 (2018) 0112. doi: 10.1038/s41570-018-0112
64. [64]
  T. Li, J.D. Cui, L.M. Gao, et al., ACS Sustain. Chem. Eng. 8 (2020) 13352–13361. doi: 10.1021/acssuschemeng.0c04089
65. [65]
  G.Y. Ryu, H. Jae, K.J. Kim, et al., ACS Appl. Energy Mater. 6 (2023) 4283–4296. doi: 10.1021/acsaem.3c00220
66. [66]
  S. Mukhopadhyay, J. Debgupta, C. Singh, et al., Angew. Chem. Int. Ed. 57 (2018) 1918–1923. doi: 10.1002/anie.201711920
67. [67]
  Y. Liu, S. Liu, X. Lai, et al., Adv. Funct. Mater. 25 (2015) 4480–4485. doi: 10.1002/adfm.201501912
68. [68]
  B. Kang, H. Tang, Z. Zhao, et al., ACS Omega 5 (2020) 6229–6239. doi: 10.1021/acsomega.0c00237
69. [69]
  Y. Fang, C. Xing, S. Zhan, et al., J. Mater. Chem. B 7 (2019) 1933–1944. doi: 10.1039/c8tb03331e
70. [70]
  S.S. Soares, H. Martins, R.O. Duarte, et al., J. Inorg. Biochem. 101 (2007) 80–88. doi: 10.1016/j.jinorgbio.2006.08.002
71. [71]
  M. Aureliano, Oxid. Med. Cell. Longev. 2016 (2016) 6103457. doi: 10.1155/2016/6103457
72. [72]
  D. Chang, Y. Li, Y. Chen, et al., Nanoscale Adv. 4 (2022) 3689–3706. doi: 10.1039/d2na00391k
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