Citation: Hai-Ling Wang, Bing Yu, Fu-Pei Liang, Hua-Hong Zou. Aggregation-enhanced antenna effects of dynamic chiral Eu(Ⅲ) complexes significantly enhance imaging of living cells and zebrafish[J]. Chinese Chemical Letters, ;2026, 37(9): 111346. doi: 10.1016/j.cclet.2025.111346 shu

Aggregation-enhanced antenna effects of dynamic chiral Eu(Ⅲ) complexes significantly enhance imaging of living cells and zebrafish

Hai-Ling Wang ^{a, *,} ,
Bing Yu ^b ,
Fu-Pei Liang ^b ,
Hua-Hong Zou ^{b, *,}

a.
School of Chemistry and Chemical Engineering, Guangxi Key Laboratory of Electrochemical Energy Materials, Guangxi University, Nanning 530004, China
b.
Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin 541004, China

whl2016010984@163.com

gxnuchem@foxmail.com

Received Date: 1 April 2025
Revised Date: 9 May 2025
Accepted Date: 19 May 2025
Available Online: 19 May 2025

Figures(6)

In this work, the aggregation-enhanced antenna effect of chiral mononuclear Eu(Ⅲ) complexes containing dynamic modules in aqueous solution was used for the first time to significantly improve the optical imaging performance of various types of cells and zebrafish. Specifically, the chiral mononuclear Eu(Ⅲ) complexes (R/S-1 and R/S-2) containing molecular rotors or vibration unit modules have almost negligible emission in the molecule state, but after aggregation in aqueous solution, they form nanoparticles with a sharp increase in emission peaks. It is worth noting that the above photophysical properties lead to R/S-1 and R/S-2 having high-resolution cell imaging effects on various cells, and localizing in lysosomal organelles. In addition, R/S-1 and R/S-2 also show high-resolution optical imaging effects on zebrafish. This work not only opens a door to expand the bioimaging performance of lanthanide complex emitters but also opens a new perspective for the construction of new dynamic lanthanide complexes with bright emissions.
- Dynamic chiral Eu(Ⅲ) complexes,
- Antenna effect,
- Aggregation-induced emission,
- Bioimaging,
- Solvothermal synthesis
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沈阳化工大学材料科学与工程学院沈阳 110142