Citation: Chu Zeng, Han Yang, Ming Xu, Zhi-Yuan Gu. Optimizing COF crystallinity for high-resolution GC separation[J]. Chinese Chemical Letters, ;2026, 37(1): 110064. doi: 10.1016/j.cclet.2024.110064 shu

Optimizing COF crystallinity for high-resolution GC separation

Jiangsu Key Laboratory of Biofunctional Materials, Jiangsu Collaborative Innovation Center of Biomedical Functional Materials, Jiangsu Key Laboratory of New Power Batteries, College of Chemistry and Materials Science, Nanjing Normal University, Nanjing 210023, China

mingxu@njnu.edu.cn

guzhiyuan@njnu.edu.cn

Received Date: 21 March 2024
Revised Date: 18 April 2024
Accepted Date: 27 May 2024
Available Online: 3 June 2024

Figures(4)

This research explores the influence of crystallinity on gas chromatographic (GC) separation using covalent organic frameworks (COFs) as stationary phases. Three COF materials (CTF-DCBs) with varying crystallinity were synthesized and characterized. CTF-DCB-1, with superior crystallinity, demonstrated high-selectivity GC separation of benzene isomers as well as styrene/phenylacetylene mixtures, while CTF-DCB-2 and CTF-DCB-3 exhibited lower crystallinity and worse separation performance. Thermodynamic and kinetic tests showed that CTF-DCB-1 had the worst thermodynamic adsorption but low diffusion mass transfer resistance, which resulted in the best separation. Therefore, optimizing the crystallinity of COFs is necessary for balancing the kinetic diffusion and thermodynamic interactions towards the analytes, achieving high-performance GC stationary phases.
- Covalent organic framework,
- Gas chromatography,
- Crystallinity,
- Kinetic diffusion,
- Thermodynamic adsorption
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