Citation: Lu Huang, Jiang Wang, Hong Jiang, Lanfang Chen, Huanwen Chen. On-line determination of selenium compounds in tea infusion by extractive electrospray ionization mass spectrometry combined with a heating reaction device[J]. Chinese Chemical Letters, ;2025, 36(1): 109896. doi: 10.1016/j.cclet.2024.109896 shu

On-line determination of selenium compounds in tea infusion by extractive electrospray ionization mass spectrometry combined with a heating reaction device

Lu Huang ^{a, 1} ,
Jiang Wang ^{a, 1} ,
Hong Jiang ^b ,
Lanfang Chen ^c ,
Huanwen Chen ^{a, *,}

a.
Academician Workstation, Jiangxi University of Chinese Medicine, Nanchang 330004, China
b.
Suzhou Jingcheng Precision Instrument Technology Co., Ltd., Suzhou 215228, China
c.
The First Affiliated Hospital of Nanchang University, Nanchang 330006, China

Received Date: 18 November 2023
Revised Date: 21 March 2024
Accepted Date: 16 April 2024
Available Online: 16 April 2024

Figures(4)

Selenium is one of the important trace elements in the human body. Its deficiency will directly affect human health. With people's attention to health, the content of selenium in food has gradually attracted attention. However, detecting selenium compounds in complex samples remains a challenge. In this work, we built an online heating-reaction device. This device combines the electrospray extraction ionization mass spectrometry (EESI-MS) with the heating reaction device, which can simultaneously detect various selenium compounds in complex liquid samples. Under acidic conditions, the sample was heated and catalyzed by a heating reaction device, so that the SeO₃²⁻ and O-phenylenediamine (OPD) could generate 1,3-dihydro-2,1,3-benzoselenadiazole. Based on the above reactions, we can detect organic selenium, inorganic selenium and other compounds in liquid samples by organic mass spectrometry. In this experiment, we determined the content of three forms of selenium: selenomethionine (SeMet), l-selenocystine (SeCys(2)), and sodium selenite. The calibration curves for SeMet, SeCys(2), and sodium selenite showed strong linearity within a range of 0.50–50.00 µg/L. The limits of detection (LOD) for the three compounds were 0.22, 0.27, and 0.41 µg/L, respectively. The limits of quantification (LOQ) were 0.68, 0.81, and 1.23 µg/L, respectively. Spiked recoveries at three levels ranged from 98.8% to 106.1%. In addition, this method can simultaneously detect three selenium compounds and three other specific chemical components in tea infusion samples, providing a rapid and efficient method for identifying tea quality.
- Heating reaction device,
- Extractive electrospray ionization mass spectrometry,
- Inorganic selenium,
- Selenium compounds,
- Tea infusion
1. [1]
  P. Olmedo, A.F. Hernandez, A. Pla, et al., Food Chem. 62 (2013) 299–307. doi: 10.1016/j.fct.2013.08.076
2. [2]
  N.V. Dolgova, S. Nehzati, T.C. MacDonald, et al., Metallomics 11 (2019) 621–631. doi: 10.1039/c8mt00315g
3. [3]
  H. Jiang, W. Lin, H. Jiao, et al., Metallomics 13 (2021) mfab040. doi: 10.1093/mtomcs/mfab040
4. [4]
  X. Shang, Q. Sun, Y. Yin, et al., Aquac. Rep. 19 (2021) 100609. doi: 10.1016/j.aqrep.2021.100609
5. [5]
  W. Lv, Environ. Pollut. 291 (2021) 118259. doi: 10.1016/j.envpol.2021.118259
6. [6]
  J. Hou, L. Zhu, C. Chen, et al., J. Trace Elem. Med. Biol. 68 (2021) 126832. doi: 10.1016/j.jtemb.2021.126832
7. [7]
  B.K. Shimada, N. Alfulaij, L.A. Seale, Int. J. Mol. Sci. 22 (2021) 10713. doi: 10.3390/ijms221910713
8. [8]
  R.F. Clark, E. Strukle, S.R. Williams, et al., Clin. Chim. Acta 275 (1996) 1087–1088. doi: 10.1001/jama.1996.03530380029025
9. [9]
  N. Hadrup, G. Ravn-Haren, J. Trace Elem. Med. Biol. 58 (2020) 126435. doi: 10.1016/j.jtemb.2019.126435
10. [10]
  M. Kieliszek, S. Błażejak, Nutrition 29 (2013) 713–718. doi: 10.1016/j.nut.2012.11.012
11. [11]
  A. Razaghi, M. Poorebrahim, D. Sarhan, et al., Eur. J. Cancer 155 (2021) 256–267. doi: 10.1016/j.ejca.2021.07.013
12. [12]
  L. Kursvietiene, A. Mongirdiene, J. Bernatoniene, et al., Antioxidants 9 (2020) 80. doi: 10.3390/antiox9010080
13. [13]
  J. Moreda-Pineiro, A. Moreda-Pineiro, V. Romaris-Hortas, et al., Food Chem. 139 (2013) 872–877. doi: 10.1016/j.foodchem.2013.01.116
14. [14]
  G.S. Banuelos, I. Arroyo, I.J. Pickering, et al., Food Chem. 166 (2015) 603–608. doi: 10.1016/j.foodchem.2014.06.071
15. [15]
  K.M. Kubachka, T. Hanley, M. Mantha, et al., Food Chem. 218 (2017) 313–320. doi: 10.1016/j.foodchem.2016.08.086
16. [16]
  M. Banerjee, D. Chakravarty, P. Kalwani, et al., J. Biochem. Mol. Toxicol. 36 (2022) e23195. doi: 10.1002/jbt.23195
17. [17]
  J. Xiang, S. Rao, Q. Chen, et al., Plants 11 (2022) 2491. doi: 10.3390/plants11192491
18. [18]
  C.S. Yang, J. Zhang, J. Agric. Food Chem. 67 (2019) 5446–5456. doi: 10.1021/acs.jafc.8b05242
19. [19]
  L. Xu, R. Wang, Y. Liu, et al., J. Funct. Foods 107 (2023) 105669. doi: 10.1016/j.jff.2023.105669
20. [20]
  W. Ding, S. Wang, J. Gu, et al., Chin. Chem. Lett. 34 (2023) 108043. doi: 10.1016/j.cclet.2022.108043
21. [21]
  X.M. Guo, S.P. Li, B.L. Huang, Spectrosc. Lett. 38 (2005) 131–143. doi: 10.1081/SL-200049589
22. [22]
  M. Diaz-Somoano, M.A. Lopez-Anton, M.R. Martinez-Tarazona, Fuel 83 (2004) 231–235. doi: 10.1016/S0016-2361(03)00259-X
23. [23]
  O. Oster, W. Prellwitz, Clin. Chim. Acta 124 (1982) 277–291. doi: 10.1016/0009-8981(82)90422-3
24. [24]
  B. Iscioglu, E. Henden, Anal. Chim. Acta 505 (2004) 101–106. doi: 10.1016/S0003-2670(03)00888-2
25. [25]
  S. Wu, J. Sun, H. Zhang, et al., J. Biotechnol. 136 (2008) S724-S724.
26. [26]
  G. Moreno-Martin, J. Sanz-Landaluze, M.E. León-Gonzalez, et al., Anal. Chim. Acta 1081 (2019) 72–80. doi: 10.1016/j.aca.2019.06.061
27. [27]
  L. Gong, Q. Xu, C. Lee, et al., Eur. Food Res. Technol. 235 (2012) 169–176. doi: 10.1007/s00217-012-1747-2
28. [28]
  B. Chen, B. Hu, M. He, et al., J. Anal. At. Spectrom. 28 (2013) 334–343. doi: 10.1039/c2ja30280b
29. [29]
  M. Dernovics, R. Lobinski, Anal. Chem. 80 (2008) 3975–3984. doi: 10.1021/ac8002038
30. [30]
  X. Zhi-Ming, S. Rong, J. Zheng, et al., Chin. J. Anal. Chem. 42 (2014) 1314–1319.
31. [31]
  X. Zhang, L. Yang, Z. Mester, Anal. Chim. Acta 744 (2012) 54–59. doi: 10.1016/j.aca.2012.07.011
32. [32]
  S. Topal, M. Oner, B.T. Zaman, et al., New J. Chem. 47 (2023) 14520–14527. doi: 10.1039/d3nj01949g
33. [33]
  M. Kotrebai, J.F. Tyson, E. Block, et al., J. Chromatogr. A 866 (2000) 51–63. doi: 10.1016/S0021-9673(99)01060-2
34. [34]
  K. Bierla, M. Dernovics, V. Vacchina, et al., Anal. Bioanal. Chem. 390 (2008) 1789–1798. doi: 10.1007/s00216-008-1883-5
35. [35]
  Y. Khanhuathon, W. Siriangkhawut, P. Chantiratikul, et al., Anal. Lett. 46 (2013) 1779–1792. doi: 10.1080/00032719.2013.775652
36. [36]
  C. Meng, G. Zhu, C. Ke, et al., Chin. Chem. Lett. 33 (2022) 2086–2090. doi: 10.1016/j.cclet.2021.08.094
37. [37]
  L. Yuan, G. Yuan, Z. Bin, et al., Chin. Chem. Lett. 33 (2022) 2708–2710. doi: 10.1016/j.cclet.2021.08.119
38. [38]
  Z. Qin, X. Hua, Z. Jin, et al., Chin. Chem. Lett. 33 (2022) 4746–4749. doi: 10.1016/j.cclet.2022.01.004
39. [39]
  M. Zi, G. Yuan, C. Feng, et al., Chin. Chem. Lett. 33 (2022) 4411–4414. doi: 10.1016/j.cclet.2021.12.029
40. [40]
  C. Huan, H. Bin, Z. Xie, Chinese J. Anal. Chem. 38 (2010) 1069–1088. doi: 10.1016/S1872-2040(09)60060-8
41. [41]
  T.M. Johnson, T.D. Bullen, P.T. Zawislanski, Environ. Sci. Technol. 34 (2000) 2075–2079. doi: 10.1021/es990187y
42. [42]
  K. Schilling, T.M. Johnson, W. Wilcke, Environ. Sci. Technol. 45 (2011) 2670–2676. doi: 10.1021/es102926p
43. [43]
  K. Schilling, T.M. Johnson, K.S. Dhillon, et al., Environ. Sci. Technol. 49 (2015) 9690–9698. doi: 10.1021/acs.est.5b00477
44. [44]
  X. Zou, K. Shen, C. Wang, et al., J. Food Compost. Anal. 106 (2022) 104333. doi: 10.1016/j.jfca.2021.104333
45. [45]
  T. Lindemann, H. Hintelmann, Anal. Bioanal. Chem. 372 (2002) 486–490. doi: 10.1007/s00216-001-1113-x
46. [46]
  A. Shrivastava, V. Gupta, Chron. Young Sci. 2 (2011) 21–25. doi: 10.4103/2229-5186.79345
47. [47]
  H.W. Chen, A. Venter, R.G. Cooks, Chem. Commun. 19 (2006) 2042–2044. doi: 10.1039/b602614a
48. [48]
  M. Qin, Y. Qian, L. Huang, et al., Front. Pharmacol. 14 (2023) 1110900. doi: 10.3389/fphar.2023.1110900
49. [49]
  S. Wang, F. Li, Y. Liu, et al., Anal. Bioanal. Chem. 411 (2019) 4049–4054. doi: 10.1007/s00216-018-1520-x
50. [50]
  Y. Zhu, F. Wang, Y. Zhao, et al., J. Chromatogr. B 1198 (2022) 123248. doi: 10.1016/j.jchromb.2022.123248
51. [51]
  C. Wang, R. Feng, D. Sun, et al., J. Chromatogr. B 879 (2011) 2871–2876. doi: 10.1016/j.jchromb.2011.08.014
52. [52]
  D. Turkozu, N. Sanlier, Crit. Rev. Food Sci. Nutr. 57 (2017) 1681–1687. doi: 10.1080/10408398.2015.1016141
53. [53]
  L. Paiva, E. Lima, M. Motta, et al., Curr. Res. Food Sci. 3 (2020) 227–234. doi: 10.1016/j.crfs.2020.07.004
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