Citation: Tingting Hu, Chao Shen, Xueyan Wang, Fengbo Wu, Zhiyao He. Tumor microenvironment-sensitive polymeric nanoparticles for synergetic chemo-photo therapy[J]. Chinese Chemical Letters, ;2024, 35(11): 109562. doi: 10.1016/j.cclet.2024.109562 shu

Tumor microenvironment-sensitive polymeric nanoparticles for synergetic chemo-photo therapy

Tingting Hu ^{a, 1} ,
Chao Shen ^{a, 1} ,
Xueyan Wang ^a ,
Fengbo Wu ^{a, b, *,} ,
Zhiyao He ^{a, b, *,}

a.
Department of Pharmacy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China
b.
Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, China

fbwu2013@scu.edu.cn

zhiyaohe@scu.edu.cn

Received Date: 17 November 2023
Revised Date: 23 January 2024
Accepted Date: 24 January 2024
Available Online: 26 January 2024

Figures(8)

Nanoparticles that employ stimuli-responsive polymeric delivery carriers have emerged as intelligent nanoplatforms with great potential in cancer theranostics, mainly including cancer diagnosis, controlled/triggered drug delivery, and real-time monitoring of therapeutic response. Particularly, tumor microenvironment (TME)-responsive polymeric nanocarriers in response to weak acidity, hypoxia, reactive oxygen species (ROS), glutathione (GSH), or tumor enzymes in the TME show great promise in facilitating tumor accumulation, enhancing tumor penetration, prolonging tumor retention, and achieving controlled drug release, thereby improving the efficiency of tumor therapy. Besides, the combination of chemotherapy and phototherapy presents a promising endeavor for the treatment of tumors, which allows for the integration of the advantages of each treatment modality, addressing the shortcomings of the two methods, and amplifying the efficacy of tumor treatment while reducing adverse reactions. This review focuses on the latest progress in the development of TME-responsive polymeric nanoparticles for synergetic chemo-photo therapy, and discusses the critical challenges and future considerations involved in the fabrication of TME-responsive nanocarriers.
- Polymeric nanoparticles,
- Tumor microenvironment-sensitive,
- Chemotherapy,
- Photothermal therapy,
- photodynamic therapy,
- Combination therapy
1. [1]
  C. Xia, X. Dong, H. Li, et al., Chin. Med. J. 135 (2022) 584–590. doi: 10.1097/CM9.0000000000002108
2. [2]
  M. Ashrafizadeh, M. Delfi, A. Zarrabi, et al., J. Control. Release 351 (2022) 50–80. doi: 10.1016/j.jconrel.2022.08.001
3. [3]
  Q. Wu, Z. Yang, Y. Nie, et al., Cancer Lett. 347 (2014) 159–166. doi: 10.1016/j.canlet.2014.03.013
4. [4]
  Y. Wang, Y. Zhang, X. Zhang, et al., Pharmaceutics 14 (2022) 1735. doi: 10.3390/pharmaceutics14081735
5. [5]
  H. Wang, L. Gao, T. Fan, et al., ACS Appl. Mater. Interfaces 13 (2021) 54621–54647. doi: 10.1021/acsami.1c13634
6. [6]
  M. Yu, R. Cao, Z. Ma, M. Zhu, J. Mater. Chem. B 11 (2023) 1416–1433. doi: 10.1039/D2TB02248F
7. [7]
  L. Menilli, C. Milani, E. Reddi, F. Moret, Cancers 14 (2022) 4462. doi: 10.3390/cancers14184462
8. [8]
  W. Fan, B. Yung, P. Huang, X. Chen, Chem. Rev. 117 (2017) 13566–13638. doi: 10.1021/acs.chemrev.7b00258
9. [9]
  M. Overchuk, R.A. Weersink, B.C. Wilson, G. Zheng, ACS Nano 17 (2023) 7979–8003. doi: 10.1021/acsnano.3c00891
10. [10]
  J.P.J. Merlin, A. Crous, H. Abrahamse, Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol. 16 (2023) e1930.
11. [11]
  H. Luo, S. Gao, J. Control. Release 362 (2023) 425–445. doi: 10.1016/j.jconrel.2023.08.056
12. [12]
  S. He, X. Jia, S. Feng, J. Hu, Small 19 (2023) e2300078. doi: 10.1002/smll.202300078
13. [13]
  Y.T. Zhong, Y. Cen, L. Xu, et al., Adv. Healthc. Mater. 12 (2023) e2202307. doi: 10.1002/adhm.202202307
14. [14]
  D. Meng, S. Yang, Y. Yang, et al., J. Control. Release 352 (2022) 146–162. doi: 10.1016/j.jconrel.2022.10.019
15. [15]
  J. Cao, Z. Chen, J. Chi, et al., Artif. Cells Nanomed. Biotechnol. 46 (2018) 817–830.
16. [16]
  L. Zhang, Y. Zhang, Y. Xue, et al., Adv. Mater. 31 (2019) e1805936. doi: 10.1002/adma.201805936
17. [17]
  J. Beik, Z. Abed, F.S. Ghoreishi, et al., J. Control. Release 235 (2016) 205–221. doi: 10.1016/j.jconrel.2016.05.062
18. [18]
  L. Wu, X. Cai, H. Zhu, et al., Adv. Funct. Mater. 28 (2018) 04324.
19. [19]
  H. Gao, Z. Cao, H. Liu, et al., Theranostics 13 (2023) 1974–2014. doi: 10.7150/thno.80887
20. [20]
  M.J. Mitchell, M.M. Billingsley, R.M. Haley, et al., Nat. Rev. Drug Discov. 20 (2021) 101–124. doi: 10.1038/s41573-020-0090-8
21. [21]
  S. Fan, H. Han, Z. Yan, et al., Med. Rev. 3 (2023) 230–269. doi: 10.1515/mr-2023-0020
22. [22]
  R. Liu, C. Luo, Z. Pang, et al., Chin. Chem. Lett. 34 (2023) 107518. doi: 10.1016/j.cclet.2022.05.032
23. [23]
  R. De, M.K. Mahata, K.T. Kim, Adv. Sci. 9 (2022) e2105373. doi: 10.1002/advs.202105373
24. [24]
  L. Mao, P. Ma, X. Luo, et al., ACS Nano 17 (2023) 9826–9849. doi: 10.1021/acsnano.3c02273
25. [25]
  Y. Chen, Q. Zeng, B. Chu, et al., Chin. Chem. Lett. 34 (2023) 108133. doi: 10.1016/j.cclet.2023.108133
26. [26]
  F. Hu, J. Qi, Y. Lu, et al., Chin. Chem. Lett. 34 (2023) 108250. doi: 10.1016/j.cclet.2023.108250
27. [27]
  A.K. Tewari, S.C. Upadhyay, M. Kumar, et al., Polymers 14 (2022) 3545. doi: 10.3390/polym14173545
28. [28]
  M. Wang, T. Wang, P. Cai, X. Chen, Small Methods 3 (2019) e1900025. doi: 10.1002/smtd.201900025
29. [29]
  Z. Hong, X. Zan, T. Yu, et al., Chin. Chem. Lett. 34 (2023) 107603. doi: 10.1016/j.cclet.2022.06.026
30. [30]
  M. Li, W. Zhang, J. Li, et al., Chin. Chem. Lett. 34 (2023) 108177. doi: 10.1016/j.cclet.2023.108177
31. [31]
  S. Luo, Z. Lv, Q. Yang, et al., Pharmaceutics 15 (2023) 1928. doi: 10.3390/pharmaceutics15071928
32. [32]
  J. Xu, Y. Lai, F. Wang, et al., Chin. Chem. Lett. 34 (2023) 108332. doi: 10.1016/j.cclet.2023.108332
33. [33]
  Y. Li, X. Zhang, X. Liu, et al., Chem. Sci. 12 (2021) 3130–3145. doi: 10.1039/D0SC06557A
34. [34]
  S. Peng, F. Xiao, M. Chen, H. Gao, Adv. Sci. 9 (2022) e2103836. doi: 10.1002/advs.202103836
35. [35]
  M. Fane, A.T. Weeraratna, Nat. Rev. Cancer 20 (2020) 89–106. doi: 10.1038/s41568-019-0222-9
36. [36]
  H. Park, G. Saravanakumar, J. Kim, et al., Adv. Healthc. Mater. 10 (2021) e2000834. doi: 10.1002/adhm.202000834
37. [37]
  Y. Yang, H. Wu, B. Liu, Z. Liu, Adv. Drug Deliv. Rev. 179 (2021) 114004. doi: 10.1016/j.addr.2021.114004
38. [38]
  F. Klemm, J.A. Joyce, Trends Cell Biol. 25 (2015) 198–213. doi: 10.1016/j.tcb.2014.11.006
39. [39]
  H. Fang, Y.A. Declerck, Cancer Res. 73 (2013) 4965–4977.
40. [40]
  M.G. Vander Heiden, L.C. Cantley, C.B. Thompson, Science 324 (2009) 1029–1033. doi: 10.1126/science.1160809
41. [41]
  A. Anemone, L. Consolino, F. Arena, et al., Cancer Metastasis Rev. 38 (2019) 25–49. doi: 10.1007/s10555-019-09782-9
42. [42]
  Y. Wang, K. Zhou, G. Huang, et al., Nat. Mater. 13 (2014) 204–212. doi: 10.1038/nmat3819
43. [43]
  X. Pang, Y. Jiang, Q. Xiao, et al., J. Control. Release 222 (2016) 116–129. doi: 10.1016/j.jconrel.2015.12.024
44. [44]
  Y. Li, K. Tang, X. Zhang, et al., Chem. Commun. 58 (2022) 8754–8765. doi: 10.1039/D2CC02759C
45. [45]
  D.M. Gilkes, G.L. Semenza, D. Wirtz, Nat. Rev. Cancer 14 (2014) 430–439. doi: 10.1038/nrc3726
46. [46]
  V. Petrova, M. Annicchiarico-Petruzzelli, G. Melino, I. Amelio, Oncogenesis 7 (2018) 10. doi: 10.1038/s41389-017-0011-9
47. [47]
  P. Vaupel, K. Schlenger, C. Knoop, M. Hockel, Cancer Res. 51 (1991) 3316–3322.
48. [48]
  G. Gruber, R.H. Greiner, R. Hlushchuk, et al., Breast Cancer Res. 6 (2004) R191–R198. doi: 10.1186/bcr775
49. [49]
  H. Wang, J. Li, Y. Wang, et al., J. Control. Release 319 (2020) 25–45. doi: 10.1016/j.jconrel.2019.12.028
50. [50]
  C.D. Phung, T.H. Tran, L.M. Pham, et al., J. Control. Release 324 (2020) 413–429. doi: 10.1016/j.jconrel.2020.05.029
51. [51]
  J. Yin, H. Cao, H. Wang, et al., Acta Pharm. Sin. B 10 (2020) 2246–2257. doi: 10.1016/j.apsb.2020.06.004
52. [52]
  Z. Li, P. Liu, W. Chen, et al., J. Nanobiotechnol. 21 (2023) 221. doi: 10.1186/s12951-023-01939-7
53. [53]
  E. Panieri, M.M. Santoro, Cell Death Dis. 7 (2016) e2253. doi: 10.1038/cddis.2016.105
54. [54]
  W.S. Wu, Cancer Metastasis Rev. 25 (2006) 695–705.
55. [55]
  F. Weinberg, N. Ramnath, D. Nagrath, Cancers 11 (2019) 1191. doi: 10.3390/cancers11081191
56. [56]
  M.T. Elnakish, H.H. Hassanain, P.M. Janssen, et al., J. Pathol. 231 (2013) 290–300. doi: 10.1002/path.4255
57. [57]
  N. Yang, W. Xiao, X. Song, et al., Nano Micro Lett. 12 (2020) 15. doi: 10.1007/s40820-019-0347-0
58. [58]
  Z. Cao, D. Li, J. Wang, X. Yang, Acta Biomater. 130 (2021) 17–31. doi: 10.1016/j.actbio.2021.05.023
59. [59]
  G. Lian, J.R. Gnanaprakasam, T. Wang, et al., eLife 7 (2018) e36158. doi: 10.7554/eLife.36158
60. [60]
  F. Gong, L. Cheng, N. Yang, et al., Nano Lett. 18 (2018) 6037–6044. doi: 10.1021/acs.nanolett.8b02933
61. [61]
  Y. Liu, Y. Tian, Y. Tian, et al., Adv. Mater. 27 (2015) 7156–7160. doi: 10.1002/adma.201503662
62. [62]
  S. Peng, Y. Men, R. Xie, et al., J. Colloid Interface Sci. 539 (2019) 19–29. doi: 10.1016/j.jcis.2018.12.035
63. [63]
  Y. Yang, W. Sun, Nanoscale Adv. 4 (2022) 3504–3516. doi: 10.1039/D2NA00222A
64. [64]
  M. Shahriari, M. Zahiri, K. Abnous, et al., J. Control. Release 308 (2019) 172–189. doi: 10.1016/j.jconrel.2019.07.004
65. [65]
  D.S. Chu, R.N. Johnson, S.H. Pun, J. Control. Release 157 (2012) 445–454. doi: 10.1016/j.jconrel.2011.10.016
66. [66]
  L. Luo, F. Xu, H. Peng, et al., J. Control. Release 318 (2020) 124–135. doi: 10.1016/j.jconrel.2019.12.017
67. [67]
  X. Chen, H. Gao, Y. Deng, et al., ACS Nano 14 (2020) 5121–5134. doi: 10.1021/acsnano.0c02197
68. [68]
  J. Deng, A. Walther, Adv. Mater. 32 (2020) e2002629. doi: 10.1002/adma.202002629
69. [69]
  E. Sameiyan, E. Bagheri, S. Dehghani, et al., Acta Biomater. 123 (2021) 110–122. doi: 10.1016/j.actbio.2020.12.057
70. [70]
  J. Lai, B.P. Shah, Y. Zhang, et al., ACS Nano 9 (2015) 5234–5245. doi: 10.1021/acsnano.5b00641
71. [71]
  X. Zhang, K. Achazi, R. Haag, Adv. Healthc. Mater. 4 (2015) 585–592. doi: 10.1002/adhm.201400550
72. [72]
  M. Naito, T. Ishii, A. Matsumoto, et al., Angew. Chem. Int. Ed. 51 (2012) 10751–10755. doi: 10.1002/anie.201203360
73. [73]
  R. Mo, T. Jiang, R. DiSanto, et al., Nat. Commun. 5 (2014) 3364. doi: 10.1038/ncomms4364
74. [74]
  Y. Zhang, Y. Lu, F. Wang, et al., Small 13 (2017) e1602494. doi: 10.1002/smll.201602494
75. [75]
  G. Gao, Y.W. Jiang, W. Sun, et al., Small 15 (2019) e1900501. doi: 10.1002/smll.201900501
76. [76]
  J. Li, Y. Wang, C. Xu, et al., Acta Biomater. 134 (2021) 546–558. doi: 10.1016/j.actbio.2021.04.022
77. [77]
  M. Xu, C.Y. Zhang, J. Wu, et al., ACS Appl. Mater. Interfaces 11 (2019) 5701–5713. doi: 10.1021/acsami.8b13059
78. [78]
  S. Xiong, Z. Wang, J. Liu, et al., Colloids Surf. B: Biointerfaces 173 (2019) 346–355. doi: 10.1016/j.colsurfb.2018.10.012
79. [79]
  R. Yan, X. Liu, J. Xiong, et al., RSC Adv. 10 (2020) 13889–13899. doi: 10.1039/D0RA01241F
80. [80]
  D. Yu, Y. Wang, J. Chen, et al., Acta Biomater. 137 (2022) 238–251. doi: 10.1016/j.actbio.2021.10.009
81. [81]
  P. Husni, Y. Shin, H. Jeon, et al., J. Control. Release 359 (2023) 52–68. doi: 10.1016/j.jconrel.2023.05.025
82. [82]
  Z. Li, X. Shan, Z. Chen, et al., Adv. Sci. 8 (2020) 2002589.
83. [83]
  H. Yang, Z. Tong, S. Sun, Z. Mao, J. Control. Release 328 (2020) 28–44. doi: 10.1016/j.jconrel.2020.08.024
84. [84]
  Z. Zhang, T. Wang, R. Yang, et al., ACS Appl. Mater. Interfaces 12 (2020) 38499–38511. doi: 10.1021/acsami.0c06872
85. [85]
  L. Hu, C. Xiong, G. Wei, et al., J. Colloid Interface Sci. 608 (2022) 1882–1893. doi: 10.1016/j.jcis.2021.10.070
86. [86]
  X. Wang, Y. Gu, Q. Li, et al., Colloids Surf. B: Biointerfaces 209 (2022) 112164. doi: 10.1016/j.colsurfb.2021.112164
87. [87]
  S. Hao, J. Zuo, H. Huang, et al., Int. J. Biol. Macromol. 242 (2023) 124048. doi: 10.1016/j.ijbiomac.2023.124048
88. [88]
  N. Jia, W. Li, D. Liu, et al., Mol. Pharm. 17 (2020) 1516–1526. doi: 10.1021/acs.molpharmaceut.9b01189
89. [89]
  S. Li, Y. Gan, C. Lin, et al., ACS Appl. Bio Mater. 4 (2021) 1605–1615. doi: 10.1021/acsabm.0c01451
90. [90]
  G. Guedes, S. Wang, F. Fontana, et al., Adv. Mater. 33 (2021) e2007761. doi: 10.1002/adma.202007761
91. [91]
  Z. Chen, F. Han, Y. Du, et al., Signal Transduct. Target. Ther. 8 (2023) 70. doi: 10.1038/s41392-023-01332-8
92. [92]
  L. Hou, X. Gong, J. Yang, et al., Adv. Mater. 34 (2022) e2200389. doi: 10.1002/adma.202200389
93. [93]
  M. Liao, F. Chen, L. Chen, et al., Small 19 (2023) e2302744. doi: 10.1002/smll.202302744
94. [94]
  M. Jiang, B. Qin, L. Luo, et al., J. Control. Release 335 (2021) 408–419. doi: 10.1016/j.jconrel.2021.06.001
95. [95]
  Z. Li, M. Wu, H. Bai, et al., Chem. Commun. 54 (2018) 13127–13130. doi: 10.1039/C8CC08445A
96. [96]
  R. Huang, D. Fan, H. Cheng, et al., Int. J. Nanomed. 18 (2023) 3359–3375. doi: 10.2147/IJN.S415139
97. [97]
  D. Hao, Q. Meng, B. Jiang, et al., ACS Nano 16 (2022) 14693–14702. doi: 10.1021/acsnano.2c05341
98. [98]
  K. Yang, L. Yue, G. Yu, et al., Biomaterials 275 (2021) 120822. doi: 10.1016/j.biomaterials.2021.120822
99. [99]
  Y. Li, J. Jeon, J.H. Park, Cancer Lett. 490 (2020) 31–43. doi: 10.1016/j.canlet.2020.05.032
100. [100]
  X. Li, N. Kwon, T. Guo, et al., Angew. Chem. Int. Ed. 57 (2018) 11522–11531. doi: 10.1002/anie.201805138
101. [101]
  J. Yin, C. Wang, L. Zhao, et al., Biomaterials 296 (2023) 122094. doi: 10.1016/j.biomaterials.2023.122094
102. [102]
  C. Song, W. Xu, Z. Wei, et al., J. Mater. Chem. B 8 (2020) 648–654. doi: 10.1039/C9TB02248A
103. [103]
  H. Xu, Y. Han, G. Zhao, et al., ACS Appl. Mater. Interfaces 12 (2020) 52319–52328. doi: 10.1021/acsami.0c12971
104. [104]
  Z. Zhang, J. Feng, T. Zhang, et al., Front. Bioeng. Biotechnol. 11 (2023) 1197404. doi: 10.3389/fbioe.2023.1197404
105. [105]
  I. Ekladious, Y.L. Colson, M.W. Grinstaff, Nat. Rev. Drug Discov. 18 (2018) 273–294.
106. [106]
  D. Dutta, Q. Zhou, J.F. Mukerabigwi, et al., Biomacromolecules 22 (2021) 4857–4870. doi: 10.1021/acs.biomac.1c01152
107. [107]
  Q. Zhou, F. Mohammed, Y. Wang, et al., J. Control. Release 339 (2021) 130–142. doi: 10.1016/j.jconrel.2021.09.023
108. [108]
  K. Zhang, X. Meng, Z. Yang, et al., Biomaterials 258 (2020) 120278. doi: 10.1016/j.biomaterials.2020.120278
109. [109]
  W. Yu, C. Hu, H. Gao, A.C.S. Appl, Bio Mater. 3 (2020) 5455–5462.
110. [110]
  J. Sun, J. Li, X. Li, et al., Chin. Chem. Lett. 34 (2023) 107891. doi: 10.1016/j.cclet.2022.107891
111. [111]
  G. Yang, S.Z.F. Phua, W.Q. Lim, et al., Adv. Mater. 31 (2019) e1901513. doi: 10.1002/adma.201901513
112. [112]
  Z. Xu, C. Pan, W. Yuan, Biomater. Sci. 8 (2020) 3348–3358. doi: 10.1039/D0BM00328J
113. [113]
  M. Ding, Y. Fan, Y. Lv, et al., Acta Biomater. 149 (2022) 334–346. doi: 10.1016/j.actbio.2022.06.041
114. [114]
  X. Zhang, H. Gao, D. Wei, et al., ACS Appl. Mater. Interfaces 15 (2023) 29827–29840. doi: 10.1021/acsami.3c03068
115. [115]
  M. Ding, Y. Zhang, N. Yu, et al., Adv. Mater. 35 (2023) e2302508. doi: 10.1002/adma.202302508
116. [116]
  J. He, Y. Chen, L. Zhang, J. Tan, Chin. Chem. Lett. 34 (2023) 107344. doi: 10.1016/j.cclet.2022.03.067
117. [117]
  M. He, Z. Zhang, Z. Jiao, et al., Chin. Chem. Lett. 34 (2023) 107574. doi: 10.1016/j.cclet.2022.05.088
118. [118]
  Y. Kim, S. Uthaman, S. Pillarisetti, et al., Acta Biomater. 108 (2020) 273–284. doi: 10.1016/j.actbio.2020.03.027
119. [119]
  S. Diao, Y. Liu, Z. Guo, et al., Adv. Healthc. Mater. 12 (2023) e2301732. doi: 10.1002/adhm.202301732
120. [120]
  Y. Ye, H. Yu, B. Chen, et al., J. Colloid Interface Sci. 645 (2023) 882–894. doi: 10.1016/j.jcis.2023.05.003
121. [121]
  S. Tang, G. Li, H. Zhang, et al., Biomater. Sci. 11 (2023) 3128–3143. doi: 10.1039/D3BM00124E
122. [122]
  G. Wang, Y. Su, X. Chen, et al., Bioact. Mater. 25 (2023) 189–200.
123. [123]
  R. Tan, J. Ge, C. Wang, et al., Carbohydr. Polym. 311 (2023) 120748. doi: 10.1016/j.carbpol.2023.120748
124. [124]
  X. Liu, Y. Liu, Y. Guo, et al., Biomaterials 277 (2021) 121115. doi: 10.1016/j.biomaterials.2021.121115
125. [125]
  Y. Xiong, C. Xiao, Z. Li, X. Yang, Chem. Soc. Rev. 50 (2021) 6013–6041. doi: 10.1039/D0CS00718H
126. [126]
  Y. Fan, P. Xu, Q. Fang, et al., ACS Appl. Mater. Interfaces 15 (2023) 27183–27194. doi: 10.1021/acsami.3c03792
127. [127]
  L. Luo, Y. Qi, H. Zhong, et al., Acta Pharm. Sin. B 12 (2022) 424–436. doi: 10.1016/j.apsb.2021.05.003
128. [128]
  X. Ma, P. Wang, Q. Wu, et al., Adv. Healthc. Mater. 12 (2023) e2202024. doi: 10.1002/adhm.202202024
129. [129]
  J. Yan, W. Jiang, G. Kang, et al., Biomater. Sci. 11 (2023) 5819–5830. doi: 10.1039/D3BM00889D
130. [130]
  Q. Kou, Y. Huang, Y. Su, et al., Nanoscale 15 (2023) 9457–9476. doi: 10.1039/D3NR00542A
131. [131]
  J. Jeon, B. Yoon, A. Dey, et al., Biomaterials 295 (2023) 122064. doi: 10.1016/j.biomaterials.2023.122064
132. [132]
  Z. Su, H. Xu, Y. Zhang, et al., J. Mater. Chem. B 11 (2023) 4211–4226. doi: 10.1039/D3TB00384A
133. [133]
  D. Huang, T. Wu, S. Lan, et al., Biomaterials 289 (2022) 121808. doi: 10.1016/j.biomaterials.2022.121808
134. [134]
  R. Han, Q. Liu, Y. Lu, et al., Biomaterials 281 (2022) 121328. doi: 10.1016/j.biomaterials.2021.121328
135. [135]
  L. Han, Y. Wang, X. Huang, et al., Biomaterials 257 (2020) 120228. doi: 10.1016/j.biomaterials.2020.120228
136. [136]
  Y. Liu, M. Zhu, M. Meng, et al., Chin. Chem. Lett. 34 (2023) 107583. doi: 10.1016/j.cclet.2022.06.006
137. [137]
  Z. Cong, L. Zhang, S.Q. Ma, et al., ACS Nano 14 (2020) 1958–1970. doi: 10.1021/acsnano.9b08434
138. [138]
  S. Hao, J. Zuo, H. Huang, et al., J. Mater. Chem. B 11 (2023) 1739–1748. doi: 10.1039/D2TB02523J
139. [139]
  Y. Shen, M. Wang, H. Wang, et al., ACS Appl. Mater. Interfaces 14 (2022) 19907–19917. doi: 10.1021/acsami.2c03687
140. [140]
  P. Tan, H. Cai, Q. Wei, et al., Biomaterials 277 (2021) 121061. doi: 10.1016/j.biomaterials.2021.121061
141. [141]
  L.K.B. Tam, J.C.H. Chu, L. He, et al., J. Am. Chem. Soc. 145 (2023) 7361–7375. doi: 10.1021/jacs.2c13732
142. [142]
  K. Wang, X. Xiao, Y. Liu, et al., Biomaterials 289 (2022) 121803. doi: 10.1016/j.biomaterials.2022.121803
143. [143]
  P. Liu, Y. Huang, C. Zhan, et al., Mater. Today Bio. 21 (2023) 100722. doi: 10.1016/j.mtbio.2023.100722
144. [144]
  A. Schmidt, D. Muller, M. Mersmann, et al., Eur. J. Biochem. 268 (2001) 1730–1738. doi: 10.1046/j.1432-1327.2001.02046.x
145. [145]
  Y. Luo, Z. Zeng, T. Shan, et al., Theranostics 12 (2022) 3610–3627. doi: 10.7150/thno.70308
146. [146]
  M. Sun, S. Yao, L. Fan, et al., Small 18 (2022) e2106296. doi: 10.1002/smll.202106296
147. [147]
  C. Yu, L. Li, P. Hu, et al., Adv. Sci. 8 (2021) 2100540. doi: 10.1002/advs.202100540
148. [148]
  M. Chen, Y. Xie, Q. Luo, et al., Chin. Chem. Lett. 34 (2023) 107744. doi: 10.1016/j.cclet.2022.107744
149. [149]
  N. Zhang, D. Wang, X. Jing, et al., ACS Appl. Bio Mater. 4 (2021) 6294–6303. doi: 10.1021/acsabm.1c00569
150. [150]
  C. Ni, Z. Ouyang, G. Li, et al., Acta Biomater 164 (2023) 474–486. doi: 10.1016/j.actbio.2023.04.003
151. [151]
  W. Jia, R. Liu, Y. Wang, et al., Acta Pharm. Sin. B 12 (2022) 3354–3366. doi: 10.1016/j.apsb.2022.03.010
152. [152]
  L.T. Geller, M. Barzily-Rokni, T. Danino, et al., Science 357 (2017) 1156–1160. doi: 10.1126/science.aah5043
153. [153]
  X. Kang, F. Bu, W. Feng, et al., Adv. Mater. 34 (2022) e2206765. doi: 10.1002/adma.202206765
154. [154]
  M. Shu, J. Tang, L. Chen, et al., Biomaterials 268 (2021) 120574. doi: 10.1016/j.biomaterials.2020.120574
155. [155]
  B. Xiao, L. Ma, D. Merlin, Expert Opin. Drug Deliv. 14 (2017) 65–73. doi: 10.1080/17425247.2016.1205583
156. [156]
  S. Gou, Y. Huang, Y. Wan, et al., Biomaterials 212 (2019) 39–54. doi: 10.1016/j.biomaterials.2019.05.012
157. [157]
  Q. Chen, Y. Ma, P. Bai, et al., ACS Appl. Mater. Interfaces 13 (2021) 4861–4873. doi: 10.1021/acsami.0c20268
1. [1]
  Wenbin Zhou , Yafei Gao , Xinyu Feng , Yanqing Zhang , Cong Yang , Lanxi He , Fenghe Zhang , Xiaoguang Li , Qing Li . Biomimetic nanoplatform integrates FRET-enhanced photodynamic therapy and chemotherapy for cascaded revitalization of the tumor immune microenvironment in OSCC. Chinese Chemical Letters, 2025, 36(1): 109763-. doi: 10.1016/j.cclet.2024.109763
2. [2]
  Yu Qin , Mingyang Huang , Chenlu Huang , Hannah L. Perry , Linhua Zhang , Dunwan Zhu . O₂-generating multifunctional polymeric micelles for highly efficient and selective photodynamic-photothermal therapy in melanoma. Chinese Chemical Letters, 2024, 35(7): 109171-. doi: 10.1016/j.cclet.2023.109171
3. [3]
  Xiangqian Cao , Chenkai Yang , Xiaodong Zhu , Mengxin Zhao , Yilin Yan , Zhengnan Huang , Jinming Cai , Jingming Zhuang , Shengzhou Li , Wei Li , Bing Shen . Synergistic enhancement of chemotherapy for bladder cancer by photothermal dual-sensitive nanosystem with gold nanoparticles and PNIPAM. Chinese Chemical Letters, 2024, 35(8): 109199-. doi: 10.1016/j.cclet.2023.109199
4. [4]
  Jialiang XU , Jiabin CUI . Recent biological applications of corroles: From diagnosis to therapy. Chinese Journal of Inorganic Chemistry, 2024, 40(12): 2303-2317. doi: 10.11862/CJIC.20240245
5. [5]
  Ningyue Xu , Jun Wang , Lei Liu , Changyang Gong . Injectable hydrogel-based drug delivery systems for enhancing the efficacy of radiation therapy: A review of recent advances. Chinese Chemical Letters, 2024, 35(8): 109225-. doi: 10.1016/j.cclet.2023.109225
6. [6]
  Leichen Wang , Anqing Mei , Na Li , Xiaohong Ruan , Xu Sun , Yu Cai , Jinjun Shao , Xiaochen Dong . Aza-BODIPY dye with unexpected bromination and high singlet oxygen quantum yield for photoacoustic imaging-guided synergetic photodynamic/photothermal therapy. Chinese Chemical Letters, 2024, 35(6): 108974-. doi: 10.1016/j.cclet.2023.108974
7. [7]
  Xuejian Xing , Pan Zhu , E Pang , Shaojing Zhao , Yu Tang , Zheyu Hu , Quchang Ouyang , Minhuan Lan . D-A-D-structured boron-dipyrromethene with aggregation-induced enhanced phototherapeutic efficiency for near-infrared fluorescent and photoacoustic imaging-guided synergistic photodynamic and photothermal cancer therapy. Chinese Chemical Letters, 2024, 35(10): 109452-. doi: 10.1016/j.cclet.2023.109452
8. [8]
  Du Liu , Yuyan Li , Hankun Zhang , Benhua Wang , Chaoyi Yao , Minhuan Lan , Zhanhong Yang , Xiangzhi Song . Three-in-one erlotinib-modified NIR photosensitizer for fluorescence imaging and synergistic chemo-photodynamic therapy. Chinese Chemical Letters, 2025, 36(2): 109910-. doi: 10.1016/j.cclet.2024.109910
9. [9]
  Cheng-Zhe Gao , Hao-Ran Jia , Tian-Yu Wang , Xiao-Yu Zhu , Xiaofeng Han , Fu-Gen Wu . A dual drug-loaded tumor vasculature-targeting liposome for tumor vasculature disruption and hypoxia-enhanced chemotherapy. Chinese Chemical Letters, 2025, 36(1): 109840-. doi: 10.1016/j.cclet.2024.109840
10. [10]
  Zhi Li , Shuya Pan , Yuan Tian , Shaowei Liu , Weifeng Wei , Jinlin Wang , Tianfeng Chen , Ling Wang . Selenium nanoparticles enhance the chemotherapeutic efficacy of pemetrexed against non-small cell lung cancer. Chinese Chemical Letters, 2024, 35(12): 110018-. doi: 10.1016/j.cclet.2024.110018
11. [11]
  Chuyu Huang , Zhishan Liu , Linping Zhao , Zuxiao Chen , Rongrong Zheng , Xiaona Rao , Yuxuan Wei , Xin Chen , Shiying Li . Metal-coordinated oxidative stress amplifier to suppress tumor growth combined with M2 macrophage elimination. Chinese Chemical Letters, 2024, 35(12): 109696-. doi: 10.1016/j.cclet.2024.109696
12. [12]
  Yongkang Yue , Zhou Xu , Kaiqing Ma , Fangjun Huo , Xuemei Qin , Kuanshou Zhang , Caixia Yin . HSA shrinkage optimizes the photostability of embedded dyes fundamentally to amplify their efficiency as photothermal materials. Chinese Chemical Letters, 2024, 35(8): 109223-. doi: 10.1016/j.cclet.2023.109223
13. [13]
  Yiqiao Chen , Ao Liu , Biwen Yang , Zhenzhen Li , Binggang Ye , Zhouyi Guo , Zhiming Liu , Haolin Chen . Photoluminescence and photothermal conversion in boric acid derived carbon dots for targeted microbial theranostics. Chinese Chemical Letters, 2024, 35(9): 109295-. doi: 10.1016/j.cclet.2023.109295
14. [14]
  Songtao Cai , Liuying Wu , Yuan Li , Soham Samanta , Jinying Wang , Bing Liu , Feihu Wu , Kaitao Lai , Yingchao Liu , Junle Qu , Zhigang Yang . Intermolecular hydrogen-bonding as a robust tool toward significantly improving the photothermal conversion efficiency of a NIR-II squaraine dye. Chinese Chemical Letters, 2024, 35(4): 108599-. doi: 10.1016/j.cclet.2023.108599
15. [15]
  Jinyu Guo , Yandai Lin , Shaohua He , Yueqing Chen , Fenglu Li , Renjie Ruan , Gaoxing Pan , Hexin Nan , Jibin Song , Jin Zhang . Utilizing dual-responsive iridium(Ⅲ) complex for hepatocellular carcinoma: Integrating photoacoustic imaging with chemotherapy and photodynamic therapy. Chinese Chemical Letters, 2024, 35(9): 109537-. doi: 10.1016/j.cclet.2024.109537
16. [16]
  Tao LIU , Yuting TIAN , Ke GAO , Xuwei HAN , Ru'nan MIN , Wenjing ZHAO , Xueyi SUN , Caixia YIN . A photothermal agent with high photothermal conversion efficiency and high stability for tumor therapy. Chinese Journal of Inorganic Chemistry, 2024, 40(8): 1622-1632. doi: 10.11862/CJIC.20240107
17. [17]
  Wei Su , Xiaoyan Luo , Peiyuan Li , Ying Zhang , Chenxiang Lin , Kang Wang , Jianzhuang Jiang . Phthalocyanine self-assembled nanoparticles for type Ⅰ photodynamic antibacterial therapy. Chinese Chemical Letters, 2024, 35(12): 109522-. doi: 10.1016/j.cclet.2024.109522
18. [18]
  Lulu Cao , Yikun Li , Dongxiang Zhang , Shuai Yue , Rong Shang , Xin-Dong Jiang , Jianjun Du . Engineering aggregates of julolidine-substituted aza-BODIPY nanoparticles for NIR-II photothermal therapy. Chinese Chemical Letters, 2024, 35(12): 109735-. doi: 10.1016/j.cclet.2024.109735
19. [19]
  Jia-Qi Feng , Xiang Tian , Rui-Ge Cao , Yong-Xiu Li , Wen-Long Liu , Rong Huang , Si-Yong Qin , Ai-Qing Zhang , Yin-Jia Cheng . An AIE-based theranostic nanoplatform for enhanced colorectal cancer therapy: Real-time tumor-tracking and chemical-enhanced photodynamic therapy. Chinese Chemical Letters, 2024, 35(12): 109657-. doi: 10.1016/j.cclet.2024.109657
20. [20]
  Haijun Shen , Yi Qiao , Chun Zhang , Yane Ma , Jialing Chen , Yingying Cao , Wenna Zheng . A matrix metalloproteinase-sensitive hydrogel combined with photothermal therapy for transdermal delivery of deferoxamine to accelerate diabetic pressure ulcer healing. Chinese Chemical Letters, 2024, 35(12): 110283-. doi: 10.1016/j.cclet.2024.110283

Get Citation

PDF

XML

Metrics

PDF Downloads(1)
Abstract views(163)
HTML views(6)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142