Citation: Xiangshuai Li, Jian Zhao, Li Luo, Zhuohao Jiao, Ying Shi, Shengli Hou, Bin Zhao. Visual and portable detection of metronidazole realized by metal-organic framework flexible sensor and smartphone scanning[J]. Chinese Chemical Letters, ;2024, 35(10): 109407. doi: 10.1016/j.cclet.2023.109407 shu

Visual and portable detection of metronidazole realized by metal-organic framework flexible sensor and smartphone scanning

Department of Chemistry, Key Laboratory of Advanced Energy Materials Chemistry, Renewable Energy Conversion and Storage Center (RECAST), Nankai University, Tianjin 300071, China

housl@nankai.edu.cn

zhaobin@nankai.edu.cn

Received Date: 1 August 2023
Revised Date: 13 November 2023
Accepted Date: 11 December 2023
Available Online: 22 December 2023

Figures(5)

Metronidazole (MNZ) is a type of antibiotic that can help people and animals cure bacterial infections, however, abuse of MNZ has posed a threat to human health. Hence, portable and visual detection of MNZ is meaningful for food safety and rational administration of drugs, but full of challenges. Hence, a porous three-dimensional Tb-based metal-organic framework (MOF) {(CH₃)₂NH₂·[Tb₅(TDA)₈(H₂O)₂]·6DMF·2C₂H₅OH}_n (TDA-Tb) with good solvent and pH stabilities was prepared, and the framework possesses one-dimensional channels with a diameter of 12 Å along the c-axis. Experiment results suggest that the synthesized TDA-Tb can selectively and sensitively detect MNZ in water, and the limit of detection (LOD) is as low as 4.1 × 10⁻⁷ mol/L. Moreover, a flexible sensor TDA-Tb-M was also constructed by incorporating TDA-Tb into membrane materials for convenient usage. And the TDA-Tb-M firstly realized portable and visual detection of MNZ through smartphone scanning, which may inspire more probes with wide application ranges.
- Metal-organic framework,
- Lanthanide,
- Luminescence,
- Antibiotic,
- Sensor
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