Citation: Ying Chen, Li Li, Junyao Zhang, Tongrui Sun, Xuan Zhang, Shiqi Zhang, Jia Huang, Yidong Zou. Tailored ionically conductive graphene oxide-encased metal ions for ultrasensitive cadaverine sensor[J]. Chinese Chemical Letters, ;2024, 35(8): 109102. doi: 10.1016/j.cclet.2023.109102 shu

Tailored ionically conductive graphene oxide-encased metal ions for ultrasensitive cadaverine sensor

Ying Chen ^{a, 1} ,
Li Li ^{a, 1} ,
Junyao Zhang ^a ,
Tongrui Sun ^a ,
Xuan Zhang ^a ,
Shiqi Zhang ^c ,
Jia Huang ^{a, b, *,} ,
Yidong Zou ^{a, *,}

a.
School of Materials Science and Engineering, Tongji University, Shanghai 201804, China
b.
Shanghai Key Laboratory of Anesthesiology and Brain Functional Modulation, Translational Research Institute of Brain and Brain-Like Intelligence, Shanghai Fourth People’s Hospital Affiliated to Tongji University, Tongji University, Shanghai 200434, China
c.
School of Mechanical Engineering, Nantong University, Nantong 226019, China

huangjia@tongji.edu.cn

ydzou@tongji.edu.cn

Received Date: 24 July 2023
Revised Date: 26 August 2023
Accepted Date: 14 September 2023
Available Online: 16 September 2023

Figures(5)

Intelligent chemical sensors have been extensively used in food safety and environmental assessment, while limited sensitivity and homogeneity bring about huge obstacles to their practical application. Herein, novel ionically conductive sensitive materials were elaborately designed based on metal ion decorated graphene oxide (GO) via a facile and general in-situ spin-coating strategy, where the abundant functional groups (-OH and -COOH) of GO layer could provide natural binding sites for various bivalent metal cations (such as Cu²⁺, Ni²⁺, Zn²⁺, Co²⁺, and Mg²⁺) through coordination and electrostatic interaction. The intercalated metal cations on the layered GO nanosheets can be regarded as charge carriers and complexation with targeted gas (cadaverine, Cad), which is a typical metabolites production and food degradants. By contrast, the designed GO@Cu(Ⅱ) sensor exhibited the optimal sensing performance toward Cad molecules at room temperature, including ultra-low detection limit (ca. 3 nL), excellent sensitivity, and rapid low concentration detection rate (only 16 s). Interestingly, the sensor exhibited an irreversible and specific response toward Cad, while it showed a transient and reversible response to other interfering gases, implying its outstanding selectivity. In addition, the GO@Cu(Ⅱ) sensor enabled real-time monitoring of the decay progression of cheese, and it exhibited great potential for large-scale production via its excellent homogeneity. It provides an efficient approach to tailoring intelligent chemical sensors for real-time food safety monitoring and human health warning.
- Graphene oxide,
- Cadaverine monitoring,
- Chemical sensor,
- Ionically conductive,
- Homogeneity
1. [1]
  K.B. Biji, C.N. Ravishankar, R. Venkateswarlu, et al., J. Food Sci. Technol. 53 (2016) 2210–2218. doi: 10.1007/s13197-016-2224-x
2. [2]
  A. Halasz, A. Barath, L. Simonsarkadi, et al., Trends Food Sci. Technol. 5 (1994) 42–49. doi: 10.1016/0924-2244(94)90070-1
3. [3]
  A. Hussain, L.R. Saraiva, D.M. Ferrero, et al., Proc. Natl. Acad. Sci. U. S. A. 110 (2013) 19579–19584. doi: 10.1073/pnas.1318596110
4. [4]
  H. Yang, D. Kim, J. Kim, et al., ACS Nano 11 (2017) 11847–11855. doi: 10.1021/acsnano.7b04992
5. [5]
  C. Ruiz-Capillas, F. Jimenez-Colmenero, Crit. Rev. Food Sci. Nutr. 44 (2004) 489–499. doi: 10.1080/10408690490489341
6. [6]
  H. Vasconcelos, J.M.M.M. de Almeida, A. Matias, et al., Trends Food Sci. Technol. 113 (2021) 86–96. doi: 10.1016/j.tifs.2021.04.043
7. [7]
  C. Ruiz-Capillas, A.M. Herrero, Foods 8 (2019) 62. doi: 10.3390/foods8020062
8. [8]
  J.H. Mah, Y.K. Park, Y.H. Jin, et al., Foods 8 (2019) 85. doi: 10.3390/foods8020085
9. [9]
  L. Prester, Food Addit. Contam. Part A Chem. Anal. Control Expo. Risk Assess. 28 (2011) 1547–1560. doi: 10.1080/19440049.2011.600728
10. [10]
  A.K. Handa, T. Fatima, A.K. Mattoo, Front. Chem. 6 (2018) 10. doi: 10.3389/fchem.2018.00010
11. [11]
  A. Onal, Food Chem. 103 (2007) 1475–1486. doi: 10.1016/j.foodchem.2006.08.028
12. [12]
  A. Romano, H. Klebanowski, S. La Guerche, et al., Food Chem. 135 (2012) 1392–1396. doi: 10.1016/j.foodchem.2012.06.022
13. [13]
  J. Sun, H.X. Guo, D. Semin, et al., J. Chromatogr. A 1218 (2011) 4689–4697. doi: 10.1016/j.chroma.2011.05.051
14. [14]
  C. Almeida, J.O. Fernandes, S.C. Cunha, Food Control 25 (2012) 380–388. doi: 10.1016/j.foodcont.2011.10.052
15. [15]
  M. Ishimaru, Y. Muto, A. Nakayama, et al., Food Anal. Methods 12 (2019) 166–175. doi: 10.1007/s12161-018-1349-0
16. [16]
  C. Proestos, P. Loukatos, M. Komaitis, Food Chem. 106 (2008) 1218–1224. doi: 10.1016/j.foodchem.2007.06.048
17. [17]
  C. Basheer, W. Wong, A. Makahleh, et al., J. Chromatogr. 1218 (2011) 4332–4339. doi: 10.1016/j.chroma.2011.04.073
18. [18]
  I. Basozabal, A. Gomez-Caballero, G. Diaz-Diaz, et al., J. Chromatogr. 1308 (2013) 45–51. doi: 10.1016/j.chroma.2013.08.002
19. [19]
  J. Donthuan, S. Yunchalard, S. Srijaranai, J. Sep. Sci. 37 (2014) 3164–3173. doi: 10.1002/jssc.201400570
20. [20]
  R.M. Ramos, I.M. Valente, J.A. Rodrigues, Talanta 124 (2014) 146–151. doi: 10.1016/j.talanta.2014.02.026
21. [21]
  Y. Chen, Y. Li, B. Feng, et al., Sens. Actuator B Chem. 360 (2022) 131662. doi: 10.1016/j.snb.2022.131662
22. [22]
  Z. Zhu, H. Liu, P. Ding, et al., ACS Sens. 8 (2022) 1318–1327.
23. [23]
  B. Feng, Y. Wu, Y. Chen, et al., ACS Appl. Nano Mater. 5 (2022) 9688–9697. doi: 10.1021/acsanm.2c01927
24. [24]
  P. Ding, H. Liu, Z. Zhu, et al., ACS Sens. 8 (2022) 2375–2382.
25. [25]
  Z. Yuan, M. Bariya, H.M. Fahad, et al., Adv. Mater. 32 (2020) 1908385. doi: 10.1002/adma.201908385
26. [26]
  T. Kim, T.H. Lee, S.Y. Park, et al., ACS Nano 17 (2023) 4404–4413. doi: 10.1021/acsnano.2c09733
27. [27]
  X. Yang, Y. Deng, H. Yang, et al., Adv. Sci. 10 (2023) 2204810. doi: 10.1002/advs.202204810
28. [28]
  L. Wang, G. Gao, Y. Zhou, et al., ACS Appl. Mater. Interfaces 11 (2019) 3506–3515. doi: 10.1021/acsami.8b20755
29. [29]
  R.L. Truby, M. Wehner, A.K. Grosskopf, et al., Adv. Mater. 30 (2018) 1706383. doi: 10.1002/adma.201706383
30. [30]
  M.S. Sarwar, Y. Dobashi, C. Preston, et al., Sci. Adv. 3 (2017) e1602200. doi: 10.1126/sciadv.1602200
31. [31]
  L. Li, S. Zhang, Y. Lu, et al., Adv. Mater. 33 (2021) e2104120. doi: 10.1002/adma.202104120
32. [32]
  Y. Lu, S. Zhang, S. Dai, et al., Matter 3 (2020) 904–919. doi: 10.1016/j.matt.2020.05.021
33. [33]
  S. Zhang, L. Li, Y. Lu, et al., J. Mater. Chem. C 10 (2022) 5497–5504. doi: 10.1039/D1TC05904A
34. [34]
  G. Jiang, M. Goledzinowski, F.J.E. Comeau, et al., Adv. Funct. Mater. 26 (2016) 1729–1736. doi: 10.1002/adfm.201504604
35. [35]
  D. Lei, Q. Zhang, N. Liu, et al., Adv. Funct. Mater. 32 (2022) 2107330. doi: 10.1002/adfm.202107330
36. [36]
  G. Eda, M. Chhowalla, Adv. Mater. 22 (2010) 2392–2415. doi: 10.1002/adma.200903689
37. [37]
  Y. Zhu, S. Murali, W. Cai, et al., Adv. Mater. 22 (2010) 3906–3924. doi: 10.1002/adma.201001068
38. [38]
  W. Yu, L. Sisi, Y. Haiyan, et al., RSC Adv. 10 (2020) 15328–15345. doi: 10.1039/D0RA01068E
39. [39]
  X.Q. Wei, L.Y. Hao, X.R. Shao, et al., ACS Appl. Mater. Interfaces 7 (2015) 13367–13374. doi: 10.1021/acsami.5b01874
40. [40]
  O.C. Compton, S.T. Nguyen, Small 6 (2010) 711–723. doi: 10.1002/smll.200901934
41. [41]
  T. Ramanathan, A.A. Abdala, S. Stankovich, et al., Nat. Nanotechnol. 3 (2008) 327–331. doi: 10.1038/nnano.2008.96
42. [42]
  Y. Long, K. Wang, G. Xiang, et al., Adv. Mater. 29 (2017) 1606093. doi: 10.1002/adma.201606093
43. [43]
  N. Boulanger, A.S. Kuzenkova, A. Iakunkov, et al., ACS Appl. Mater. Interfaces 12 (2020) 45122–45135. doi: 10.1021/acsami.0c11122
44. [44]
  P. Vazquez-Sanchez, M.A. Rodriguez-Escudero, F.J. Burgos, et al., J. Alloy. Compd. 800 (2019) 379–391. doi: 10.1016/j.jallcom.2019.06.008
45. [45]
  T. Kuilla, S. Bhadra, D. Yao, et al., Prog. Mater. Sci. 35 (2010) 1350–1375.
46. [46]
  Y. Ma, W. Shao, W. Sun, et al., Appl. Surf. Sci. 459 (2018) 544–553. doi: 10.1016/j.apsusc.2018.08.025
47. [47]
  A.S.K. Kumar, S. Jiang, J. Mol. Liq. 237 (2017) 387–401. doi: 10.1016/j.molliq.2017.04.093
48. [48]
  D.H. Carrales-Alvarado, I. Rodriguez-Ramos, R. Leyva-Ramos, et al., Chem. Eng. J. 402 (2020) 126155. doi: 10.1016/j.cej.2020.126155
49. [49]
  S. Yang, L. Li, Z. Pei, et al., Carbon 75 (2014) 227–235. doi: 10.1016/j.carbon.2014.03.057
50. [50]
  M. Deng, Z. Li, X. Deng, et al., J. Mater. Sci. Technol. 164 (2023) 150–159. doi: 10.1016/j.jmst.2023.05.007
51. [51]
  X. Liu, J. Ma, P. Jiang, et al., ACS Appl. Mater. Interfaces 12 (2020) 45332–45341. doi: 10.1021/acsami.0c13691
52. [52]
  B. Tan, B. Xiang, S. Zhang, et al., J. Colloid Interface Sci. 582 (2021) 918–931. doi: 10.1016/j.jcis.2020.08.093
53. [53]
  W. Li, W. Luo, X. Yu, et al., J. Mol. Liq. 357 (2022) 119110. doi: 10.1016/j.molliq.2022.119110
54. [54]
  Z. Liu, Q. Chu, H. Chen, et al., Colloids Surf. A 669 (2023) 131504. doi: 10.1016/j.colsurfa.2023.131504
1. [1]
  Yuanyi Zhou , Ke Ma , Jinfeng Liu , Zirun Zheng , Bo Hu , Yu Meng , Zhizhong Li , Mingshan Zhu . Is reactive oxygen species the only way for cancer inhibition over single atom nanomedicine? Autophagy regulation also works. Chinese Chemical Letters, 2024, 35(6): 109056-. doi: 10.1016/j.cclet.2023.109056
2. [2]
  Xueling Yu , Lixing Fu , Tong Wang , Zhixin Liu , Na Niu , Ligang Chen . Multivariate chemical analysis: From sensors to sensor arrays. Chinese Chemical Letters, 2024, 35(7): 109167-. doi: 10.1016/j.cclet.2023.109167
3. [3]
  Zhangran Ye , Zhixuan Yu , Jingming Yao , Lei Deng , Yunna Guo , Hantao Cui , Chongchong Ma , Chao Tai , Liqiang Zhang , Lingyun Zhu , Peng Jia . An ionically conductive and compressible sulfochloride solid-state electrolyte for stable all-solid-state lithium-based batteries. Chinese Chemical Letters, 2025, 36(8): 110272-. doi: 10.1016/j.cclet.2024.110272
4. [4]
  Chen-Xin Wang , Guang-Lei Li , Yu Hang , Dan-Feng Lu , Jian-Qi Ye , Hao Su , Bing Hou , Tao Suo , Dan Wen . Shock-resistant wearable pH sensor based on tungsten oxide aerogel. Chinese Chemical Letters, 2025, 36(7): 110502-. doi: 10.1016/j.cclet.2024.110502
5. [5]
  Tian Cao , Xuyin Ding , Qiwen Peng , Min Zhang , Guoyue Shi . Intelligent laser-induced graphene sensor for multiplex probing catechol isomers. Chinese Chemical Letters, 2024, 35(7): 109238-. doi: 10.1016/j.cclet.2023.109238
6. [6]
  Yubin Feng , Weihang Zhu , Xinting Yang , Zhe Yang , Chenke Wei , Yukai Guo , Andrew K. Whittaker , Chun Shen , Yue Zhao , Wenrui Qu , Bai Yang , Quan Lin . Amphibian-inspired conductive ionogel stabilizing in air/water as a wearable amphibious flexible sensor for drowning alarms. Chinese Chemical Letters, 2025, 36(4): 110554-. doi: 10.1016/j.cclet.2024.110554
7. [7]
  Jia-Li Xie , Tian-Jin Xie , Yu-Jie Luo , Kai Mao , Cheng-Zhi Huang , Yuan-Fang Li , Shu-Jun Zhen . Octopus-like DNA nanostructure coupled with graphene oxide enhanced fluorescence anisotropy for hepatitis B virus DNA detection. Chinese Chemical Letters, 2024, 35(6): 109137-. doi: 10.1016/j.cclet.2023.109137
8. [8]
  Yihong Li , Zhong Qiu , Lei Huang , Shenghui Shen , Ping Liu , Haomiao Zhang , Feng Cao , Xinping He , Jun Zhang , Yang Xia , Xinqi Liang , Chen Wang , Wangjun Wan , Yongqi Zhang , Minghua Chen , Wenkui Zhang , Hui Huang , Yongping Gan , Xinhui Xia . Plasma enhanced reduction method for synthesis of reduced graphene oxide fiber/Si anode with improved performance. Chinese Chemical Letters, 2024, 35(11): 109510-. doi: 10.1016/j.cclet.2024.109510
9. [9]
  Tian TIAN , Meng ZHOU , Jiale WEI , Yize LIU , Yifan MO , Yuhan YE , Wenzhi JIA , Bin HE . Ru-doped Co₃O₄/reduced graphene oxide: Preparation and electrocatalytic oxygen evolution property. Chinese Journal of Inorganic Chemistry, 2025, 41(2): 385-394. doi: 10.11862/CJIC.20240298
10. [10]
  Kezuo Di , Jie Wei , Lijun Ding , Zhiying Shao , Junling Sha , Xilong Zhou , Huadong Heng , Xujing Feng , Kun Wang . A wearable sensor device based on screen-printed chip with biofuel cell-driven electrochromic display for noninvasive monitoring of glucose concentration. Chinese Chemical Letters, 2025, 36(2): 109911-. doi: 10.1016/j.cclet.2024.109911
11. [11]
  Xiangkang Jiang , Zhixing Wang , Hong Dong , Xiang Zhang , Jin Hu , Manman Chu , Yanshuai Hong , Lei Xu , Wenjie Peng , Xiqian Yu , Jiexi Wang . An in-depth understanding of Al doping homogeneity affecting the performance of LiCoO₂ at cut-off voltage over 4.6 V. Chinese Chemical Letters, 2024, 35(12): 109553-. doi: 10.1016/j.cclet.2024.109553
12. [12]
  Fengjun Deng , Tingyu Zhao , Xiaochen Zhang , Kaiyong Feng , Ze Liu , Youlin Xiang , Yingjian Yu . Reduced graphene oxide assembled on the Si nanowire anode enabling low passivation and hydrogen evolution for long-life aqueous Si-air batteries. Chinese Chemical Letters, 2025, 36(6): 109897-. doi: 10.1016/j.cclet.2024.109897
13. [13]
  Chong Wang , Hao Xie , Rulan Xia , Xuewei Liao , Jin Wang , Huajun Yang , Chen Wang . Nanofluidic ion rectification sensor for enantioselective recognition and detection. Chinese Chemical Letters, 2025, 36(8): 110642-. doi: 10.1016/j.cclet.2024.110642
14. [14]
  Wenjing Dai , Lan Luo , Zhen Yin . Interface reconstruction of hybrid oxide electrocatalysts for seawater oxidation. Chinese Journal of Structural Chemistry, 2025, 44(3): 100442-100442. doi: 10.1016/j.cjsc.2024.100442
15. [15]
  Kang Wang , Qinglin Zhou , Weijin Li . Conductive metal-organic frameworks for electromagnetic wave absorption. Chinese Journal of Structural Chemistry, 2024, 43(10): 100325-100325. doi: 10.1016/j.cjsc.2024.100325
16. [16]
  Bei Li , Zhaoke Zheng . In situ monitoring of the spatial distribution of oxygen vacancies at the single-particle level. Chinese Journal of Structural Chemistry, 2024, 43(10): 100331-100331. doi: 10.1016/j.cjsc.2024.100331
17. [17]
  Wendi Dou , Guangying Wan , Tiefeng Liu , Lin Han , Wu Zhang , Chuang Sun , Rensheng Song , Jianhui Zheng , Yujing Liu , Xinyong Tao . Conductive composite binder for recyclable LiFePO₄ cathode. Chinese Chemical Letters, 2024, 35(11): 109389-. doi: 10.1016/j.cclet.2023.109389
18. [18]
  Salim Ullah , Jianliang Shen , Hong-Tao Xu . Innovative self-healing conductive organogel: Pioneering the future of electronics. Chinese Chemical Letters, 2025, 36(3): 110553-. doi: 10.1016/j.cclet.2024.110553
19. [19]
  Huili Zhao , Xiao Tan , Huining Chai , Lin Hu , Hongbo Li , Lijun Qu , Xueji Zhang , Guangyao Zhang . Recent advances in conductive MOF-based electrochemical sensors. Chinese Chemical Letters, 2025, 36(8): 110571-. doi: 10.1016/j.cclet.2024.110571
20. [20]
  Tiantian Long , Hongmei Luo , Jingbo Sun , Fengniu Lu , Yi Chen , Dong Xu , Zhiqin Yuan . Carbonization-engineered ultrafast chemical reaction on nanointerface. Chinese Chemical Letters, 2025, 36(3): 109728-. doi: 10.1016/j.cclet.2024.109728

Get Citation

PDF

XML

Metrics

PDF Downloads(3)
Abstract views(1306)
HTML views(49)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142