Citation: Junping Bai, Junliang Zhou, Xin Ji, Nannan Wang, Xiaochun Dong, Wei Wu, Weili Zhao. Development of environment-insensitive and highly emissive BODIPYs via installation of N, N'-dialkylsubstituted amide at meso position[J]. Chinese Chemical Letters, ;2022, 33(9): 4175-4178. doi: 10.1016/j.cclet.2022.02.017 shu

Development of environment-insensitive and highly emissive BODIPYs via installation of N, N'-dialkylsubstituted amide at meso position

Junping Bai ^a ,
Junliang Zhou ^a ,
Xin Ji ^a ,
Nannan Wang ^b ,
Xiaochun Dong ^{a, *,} ,
Wei Wu ^{a, *,} ,
Weili Zhao ^{a, b, *,}

a.
School of Pharmacy, Institutes of Integrative Medicine, Fudan University, Shanghai 201203, China
b.
Key Laboratory for Special Functional Materials of Ministry of Education, School of Materials Science and Engineering, Henan University, Kaifeng 475004, China

xcdong@fudan.edu.cn

wuwei@shmu.edu.cn

zhaoweili@fudan.edu.cn

Received Date: 31 July 2021
Revised Date: 29 January 2022
Accepted Date: 9 February 2022
Available Online: 14 February 2022

Figures(4)

Fluorescent dyes play a crucial role in fluorescence imaging and sensing technology. However, there is a dilemma that they are usually intrinsically hydrophobic which lacks of emission in water and modification with ionic groups to access water solubility may result in poor membrane permeability. Fluorescent dyes with strong fluorescence emission in both nonpolar and polar solvents are highly desirable. In this manuscript, we reported a strategy to develop fluorescent BODIPY dyes via installation of amide moiety at meso position of 1, 3, 5, 7-tetramethyl-BODIPY and discovered that N, N'-dialkylsubstituted BODIPY amides possessed highly fluorescent emission with favorable environment-insensitive properties.
- Fluorescent dyes,
- BODIPY,
- Environment-insensitive,
- Bioimaging
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