Citation: Zetao Chen, Fenni Zhang, Yanli Lu, Yaru Li, Guang Liu, Jianzhen Shan, Qingjun Liu. Bioelectronic modulation of single-wavelength localized surface plasmon resonance (LSPR) for the detection of electroactive biomolecules[J]. Chinese Chemical Letters, ;2022, 33(6): 3144-3150. doi: 10.1016/j.cclet.2021.10.027 shu

Bioelectronic modulation of single-wavelength localized surface plasmon resonance (LSPR) for the detection of electroactive biomolecules

Zetao Chen ^a ,
Fenni Zhang ^a ,
Yanli Lu ^a ,
Yaru Li ^a ,
Guang Liu ^a ,
Jianzhen Shan ^b ,
Qingjun Liu ^{a, *,}

a.
Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry, Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China
b.
The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310027, China

qjliu@zju.edu.cn

Received Date: 1 August 2021
Revised Date: 3 October 2021
Accepted Date: 12 October 2021
Available Online: 20 October 2021

Figures(5)

The simplification of localized surface plasmon resonance (LSPR) detection can further promote the development of optical biosensing application in point-of-care testing. In this study, we proposed a simple light emitting diode (LED) based single-wavelength LSPR sensor modulated with bio-electron transfers for the detection of electroactive biomolecules. Indium tin oxide electrode loaded with nanocomposites of polyaniline coated gold nanorod was used as LSPR chip, and the applied electric potential was scanned at the LSPR chip for single-wavelength LSPR biosensing. Under the scanning of applied potentials, biological electron transfer of redox reaction was employed to demonstrate the bioelectronic modulation of single-wavelength LSPR for selective electroactive biomolecule detection. Without any additional recognition material, electroactive biomolecules uric acid and dopamine were detected directly with a sensitivity of 5.05 μmol/L and 7.11 μmol/L at their specific oxidation potentials, respectively. With the simplified optical configuration and selective bioelectronic modulation, the single-wavelength LSPR sensor is promising for the development of simple, low-cost, and high specificity optical biosensor for point-of-care testing of electroactive biomolecules.
- LSPR,
- LED light,
- Bio-electron transfer,
- Electroactive biomolecule,
- Biosensor
1. [1]
  K.M. Mayer, J.H. Hafner, Chem. Rev. 111 (2011) 3828–3857. doi: 10.1021/cr100313v
2. [2]
  J.R. Mejía-Salazar, O.N. Oliveira, Chem. Rev. 118 (2018) 10617–10625. doi: 10.1021/acs.chemrev.8b00359
3. [3]
  H.M. Kim, J.H. Park, D.H. Jeong, H.Y. Lee, S.K. Lee, Sens. Actuat. B: Chem 273 (2018) 891–898. doi: 10.1016/j.snb.2018.07.007
4. [4]
  M. Lu, M. Lin, F. Wang, Y. Zhang, W. Peng, Nanomaterials 11 (2021) 1–10.
5. [5]
  A. Gowri, A.S. Rajamani, B. Ramakrishna, V.V.R. Sai, Opt. Fiber Technol. 47 (2019) 15–20. doi: 10.1016/j.yofte.2018.11.019
6. [6]
  J. Yang, A. Moraillon, A. Siriwardena, et al., Anal. Chem. 87 (2015) 3721–3728. doi: 10.1021/ac504262b
7. [7]
  B. Sepúlveda, P.C. Angelomé, L.M. Lechuga, L.M. Liz-Marzán, Nano Today 4 (2009) 244–251. doi: 10.1016/j.nantod.2009.04.001
8. [8]
  J.W. Lee, G. Ha, J. Park, et al., ACS Appl. Mater. Interfaces 12 (2020) 36339–36346. doi: 10.1021/acsami.0c08916
9. [9]
  H. Nishi, S. Hiroya, T. Tatsuma, ACS Nano 9 (2015) 6214–6221. doi: 10.1021/acsnano.5b01577
10. [10]
  L. Ran, Y. Tao, K. Guo, et al., Phys. Chem. Chem. Phys. 20 (2018) 2146–2150. doi: 10.1039/C7CP07565K
11. [11]
  T. Okazaki, T. Orii, S.Y. Tan, et al., Anal. Lett. (2021) 1951749.
12. [12]
  D. Ji, N. Xu, Z. Liu, et al., Biosens. Bioelectron. 129 (2019) 216–223. doi: 10.1016/j.bios.2018.09.082
13. [13]
  S.S. Low, Y. Pan, D. Ji, et al., Sens. Actuat. B: Chem. 308 (2020) 127718. doi: 10.1016/j.snb.2020.127718
14. [14]
  G. Xu, C. Cheng, Z. Liu, et al., Adv. Mater. Technol. 4 (2019) 1–13.
15. [15]
  M.B. Bhavsar, L. Leppik, K.M. Costa Oliveira, J.H. Barker, Front. Bioeng. Biotechnol. 8 (2020) 603. doi: 10.3389/fbioe.2020.00603
16. [16]
  M.M. Kaelberer, K.L. Buchanan, M.E. Klein, et al., Science 361 (2018) eaat5236. doi: 10.1126/science.aat5236
17. [17]
  C. Angione, Biomed. Res. Int. 2019 (2019) 8304260.
18. [18]
  N. Dalbeth, H.K. Choi, L.A.B. Joosten, et al., Nat. Rev. Dis. Prim. 5 (2019) 69. doi: 10.1038/s41572-019-0115-y
19. [19]
  P.D. Morrison, R.M. Murray, Ther. Adv. Psychopharmacol. 8 (2018) 127–135. doi: 10.1177/2045125317752915
20. [20]
  S.E. Hyman, Curr. Biol. 15 (2005) R154–R158. doi: 10.1016/j.cub.2005.02.037
21. [21]
  J.A. Jackman, A. Rahim Ferhan, N.J. Cho, Chem. Soc. Rev. 46 (2017) 3615–3660. doi: 10.1039/C6CS00494F
22. [22]
  A. Radoi, D. Compagnone, Bioelectrochemistry. 76 (2009) 126–134. doi: 10.1016/j.bioelechem.2009.06.008
23. [23]
  K. Asami, H. Nishi, T. Tatsuma, Nanoscale. 8 (2016) 14092–14096. doi: 10.1039/C6NR03709G
24. [24]
  K. Wątor, D. Dobrzyński, K. Sugimori, E. Kmiecik, Int. J. Biometeorol. 64 (2020) 815–826. doi: 10.1007/s00484-020-01871-7
25. [25]
  J.W. Jeon, J. Zhou, J.A. Geldmeier, et al., Chem. Mater. 28 (2016) 7551–7563. doi: 10.1021/acs.chemmater.6b04026
26. [26]
  N. Jiang, L. Shao, J. Wang, Adv. Mater. 26 (2014) 3282–3289. doi: 10.1002/adma.201305905
27. [27]
  A. Ray, G.E. Asturias, D.L. Kershner, et al., Synth. Met. 29 (1989) 141–150. doi: 10.1016/0379-6779(89)90289-0
28. [28]
  G. Liao, Q. Li, Z. Xu, Prog. Org. Coat. 126 (2019) 35–43. doi: 10.1016/j.porgcoat.2018.10.018
29. [29]
  S. Zhang, C. Ran, S. Chen, et al., J. Electrochem. Soc. 164 (2017) 1021–1027. doi: 10.1149/2.0551714jes
30. [30]
  J.W. Jeon, P.A. Ledin, J.A. Geldmeier, et al., Chem. Mater. 28 (2016) 2868–2881. doi: 10.1021/acs.chemmater.6b00882
31. [31]
  X.Y. Zhang, D. Han, N. Ma, et al., J. Phys. Chem. Lett. 9 (2018) 6047–6051. doi: 10.1021/acs.jpclett.8b02416
32. [32]
  B.S. Hoener, H. Zhang, T.S. Heiderscheit, J. Phys. Chem. Lett. 8 (2017) 2681–2688. doi: 10.1021/acs.jpclett.7b00945
33. [33]
  H. Gerischer, J. Phys. Chem. 95 (1991) 1356–1359. doi: 10.1021/j100156a060
34. [34]
  A. Andries, S. De Rechter, P. Janssens, D. Mekahli, A. Van Schepdael, J. Chromatogr. B. 1096 (2018) 201–207. doi: 10.1016/j.jchromb.2018.08.026
35. [35]
  P.A. Rasheed, J.S. Lee, Microchim. Acta 184 (2017) 1239–1266. doi: 10.1007/s00604-017-2183-6
36. [36]
  Q. Wang, X. Wen, J. Kong, Crit. Rev. Anal. Chem. 50 (2020) 359–375. doi: 10.1080/10408347.2019.1637711
1. [1]
  Xuhui Fan , Fan Wang , Mengjiao Li , Faiza Meharban , Yaying Li , Yuanyuan Cui , Xiaopeng Li , Jingsan Xu , Qi Xiao , Wei Luo . Visible light excitation on CuPd/TiN with enhanced chemisorption for catalyzing Heck reaction. Chinese Chemical Letters, 2025, 36(1): 110299-. doi: 10.1016/j.cclet.2024.110299
2. [2]
  Xinqiong Li , Guocheng Rao , Xi Peng , Chan Yang , Yanjing Zhang , Yan Tian , Xianghui Fu , Jia Geng . Direct detection of C9orf72 hexanucleotide repeat expansions by nanopore biosensor. Chinese Chemical Letters, 2024, 35(5): 109419-. doi: 10.1016/j.cclet.2023.109419
3. [3]
  Meiqing Yang , Lu Wang , Haozi Lu , Yaocheng Yang , Song Liu . Recent Advances of Functional Nanomaterials for Screen-Printed Photoelectrochemical Biosensors. Acta Physico-Chimica Sinica, 2025, 41(2): 100018-. doi: 10.3866/PKU.WHXB202310046
4. [4]
  Yi Liu , Zhe-Hao Wang , Guan-Hua Xue , Lin Chen , Li-Hua Yuan , Yi-Wen Li , Da-Gang Yu , Jian-Heng Ye . Photocatalytic dicarboxylation of strained C–C bonds with CO₂ via consecutive visible-light-induced electron transfer. Chinese Chemical Letters, 2024, 35(6): 109138-. doi: 10.1016/j.cclet.2023.109138
5. [5]
  Gaowa Xing , Yuting Shang , Xiaorui Wang , Zengnan Wu , Qiang Zhang , Jiebing Ai , Qiaosheng Pu , Ling Lin . A microfluidic biosensor for multiplex immunoassay of foodborne pathogens agitated by programmed audio signals. Chinese Chemical Letters, 2024, 35(10): 109491-. doi: 10.1016/j.cclet.2024.109491
6. [6]
  Yuxin Xiao , Xiaowei Wang , Yutong Yin , Fangchao Yin , Jinchao Li , Zhiyuan Hou , Mashooq Khan , Rusong Zhao , Wenli Wu , Qiongzheng Hu . Distance-based lateral flow biosensor for the quantitative detection of bacterial endotoxin. Chinese Chemical Letters, 2024, 35(12): 109718-. doi: 10.1016/j.cclet.2024.109718
7. [7]
  Qinghong Zhang , Qiao Zhao , Xiaodi Wu , Li Wang , Kairui Shen , Yuchen Hua , Cheng Gao , Yu Zhang , Mei Peng , Kai Zhao . Visible-light-induced ring-opening cross-coupling of cycloalcohols with vinylazaarenes and enones via β-C-C scission enabled by proton-coupled electron transfer. Chinese Chemical Letters, 2025, 36(2): 110167-. doi: 10.1016/j.cclet.2024.110167
8. [8]
  Chaoqun Ma , Yuebo Wang , Ning Han , Rongzhen Zhang , Hui Liu , Xiaofeng Sun , Lingbao Xing . Carbon dot-based artificial light-harvesting systems with sequential energy transfer and white light emission for photocatalysis. Chinese Chemical Letters, 2024, 35(4): 108632-. doi: 10.1016/j.cclet.2023.108632
9. [9]
  Caixia Zhu , Qing Hong , Kaiyuan Wang , Yanfei Shen , Songqin Liu , Yuanjian Zhang . Single nanozyme-based colorimetric biosensor for dopamine with enhanced selectivity via reactivity of oxidation intermediates. Chinese Chemical Letters, 2024, 35(10): 109560-. doi: 10.1016/j.cclet.2024.109560
10. [10]
  Yiming Yang , Lichao Sun , Qingfeng Zhang . Plasmonic nanocrystals with intrinsic chirality: Biomolecule-directed synthesis and applications. Chinese Journal of Structural Chemistry, 2025, 44(1): 100467-100467. doi: 10.1016/j.cjsc.2024.100467
11. [11]
  Chunxiu Yu , Zelin Wu , Hongle Shi , Lingyun Gu , Kexin Chen , Chuan-Shu He , Yang Liu , Heng Zhang , Peng Zhou , Zhaokun Xiong , Bo Lai . Insights into the electron transfer mechanisms of peroxydisulfate activation by modified metal-free acetylene black for degradation of sulfisoxazole. Chinese Chemical Letters, 2024, 35(8): 109334-. doi: 10.1016/j.cclet.2023.109334
12. [12]
  Yiqian Jiang , Zihan Yang , Xiuru Bi , Nan Yao , Peiqing Zhao , Xu Meng . Mediated electron transfer process in α-MnO₂ catalyzed Fenton-like reaction for oxytetracycline degradation. Chinese Chemical Letters, 2024, 35(8): 109331-. doi: 10.1016/j.cclet.2023.109331
13. [13]
  Yun-Xin Huang , Lin-Qian Yu , Ke-Yu Chen , Hao Wang , Shou-Yan Zhao , Bao-Cheng Huang , Ren-Cun Jin . Biochar with self-doped N to activate peroxymonosulfate for bisphenol-A degradation via electron transfer mechanism: The active edge graphitic N site. Chinese Chemical Letters, 2024, 35(9): 109437-. doi: 10.1016/j.cclet.2023.109437
14. [14]
  Quanyou Guo , Yue Yang , Tingting Hu , Hongqi Chu , Lijun Liao , Xuepeng Wang , Zhenzi Li , Liping Guo , Wei Zhou . Regulating local electron transfer environment of covalent triazine frameworks through F, N co-modification towards optimized oxygen reduction reaction. Chinese Chemical Letters, 2025, 36(1): 110235-. doi: 10.1016/j.cclet.2024.110235
15. [15]
  Xiuzheng Deng , Yi Ke , Jiawen Ding , Yingtang Zhou , Hui Huang , Qian Liang , Zhenhui Kang . Construction of ZnO@CDs@Co₃O₄ sandwich heterostructure with multi-interfacial electron-transfer toward enhanced photocatalytic CO₂ reduction. Chinese Chemical Letters, 2024, 35(4): 109064-. doi: 10.1016/j.cclet.2023.109064
16. [16]
  Tingting Liu , Pengfei Sun , Wei Zhao , Yingshuang Li , Lujun Cheng , Jiahai Fan , Xiaohui Bi , Xiaoping Dong . Magnesium doping to improve the light to heat conversion of OMS-2 for formaldehyde oxidation under visible light irradiation. Chinese Chemical Letters, 2024, 35(4): 108813-. doi: 10.1016/j.cclet.2023.108813
17. [17]
  Di An , Mingdong She , Ziyang Zhang , Ting Zhang , Miaomiao Xu , Jinjun Shao , Qian Shen , Xuna Tang . Light-responsive nanomaterials for biofilm removal in root canal treatment. Chinese Chemical Letters, 2025, 36(2): 109841-. doi: 10.1016/j.cclet.2024.109841
18. [18]
  Mingqi Wang , Shixin Fa , Jiate Yu , Guoxian Zhang , Yi Yan , Qing Liu , Qiuyu Zhang . Light-controlled protein imprinted nanospheres with variable recognition specificity. Chinese Chemical Letters, 2025, 36(2): 110124-. doi: 10.1016/j.cclet.2024.110124
19. [19]
  Yuan Liu , Boyang Wang , Yaxin Li , Weidong Li , Siyu Lu . Understanding excitonic behavior and electroluminescence light emitting diode application of carbon dots. Chinese Chemical Letters, 2025, 36(2): 110426-. doi: 10.1016/j.cclet.2024.110426
20. [20]
  Si-Hua Liu , Jun-Hao Zhou , Jian-Ke Sun . Interconnecting zero-dimensional porous organic cages into sub-8 nm nanofilm for bio-inspired separation. Chinese Journal of Structural Chemistry, 2024, 43(7): 100312-100312. doi: 10.1016/j.cjsc.2024.100312

Get Citation

PDF

XML

Metrics

PDF Downloads(6)
Abstract views(504)
HTML views(19)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142