Citation: Chaoqun Wang, Ziqiang Deng, Hu Zhang, Rui Liu, Yi Lv. Old commercialized magnetic particles new trick: Intrinsic internal standard[J]. Chinese Chemical Letters, ;2022, 33(3): 1267-1270. doi: 10.1016/j.cclet.2021.07.049 shu

Old commercialized magnetic particles new trick: Intrinsic internal standard

Chaoqun Wang ^a ,
Ziqiang Deng ^b ,
Hu Zhang ^c ,
Rui Liu ^{b, *,} ,
Yi Lv ^a

a.
Analytical & Testing Center, Sichuan University, Chengdu 610064, China
b.
Key Laboratory of Green Chemistry and Technology of Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, China
c.
Department of Gastroenterology, West China Hospital, Sichuan University, Chengdu 610041, China

liur@scu.edu.cn

Received Date: 12 May 2021
Revised Date: 1 July 2021
Accepted Date: 21 July 2021
Available Online: 29 July 2021

Figures(3)

Magnetic particles (MPs) are the most widely used commercialized engineering particles, which gained great success in various biological applications. Inspired by their intrinsic Fe isotope composition, we discovered a commercialized MPs-internal standard's novel function to realize the accurate quantification of biomolecules. The bioassay of carcinoembryonic antigen (CEA) was chosen as a modal system. The Fe isotope in MPs and Au isotope in report probes were simultaneously and sensitively detected by the elemental mass spectrometry. ¹⁹⁷Au/⁵⁷Fe isotopic ratios and CEA concentrations showed good linearity in the range of 0.6–300 ng/mL, with a detection limit of 0.09 ng/mL (3σ). The accuracy and precision of the proposed MPs-based immunoassay were greatly improved, by eliminating potential MPs loss during magnetic separation and absolute intensity fluctuations. Considering the exceptional availability and universality of commercialized MPs, the proposed method might open a new avenue for MPs' biological applications.
- Magnetic particles,
- Ratiometric,
- Immunoassay,
- ICPMS,
- Carcinoembryonic antigen
1. [1]
  M.K. Masud, J. Na, M. Younus, et al., Chem. Soc. Rev. 48 (2019) 5717-5751. doi: 10.1039/C9CS00174C
2. [2]
  C. Liu, S.F. Wu, Y.B. Yan, et al., TrAC-Trends Anal. Chem. 121 (2019) 10.
3. [3]
  H. Gu, K. Xu, C. Xu, B. Xu, Chem. Commun. (2006) 941-949.
4. [4]
  L. Zhou, X. Zhang, L. Liu, Y. Wei, J. Yuan, Chin. J. Chem. 35 (2017) 977-983. doi: 10.1002/cjoc.201600803
5. [5]
  S.E. Kim, M.V. Tieu, S.Y. Hwang, M.H. Lee, Micromachines 11 (2020) 20.
6. [6]
  M. Colombo, S. Carregal-Romero, M.F. Casula, et al., Chem. Soc. Rev. 41 (2012) 4306-4334. doi: 10.1039/c2cs15337h
7. [7]
  Y. Guo, Y. Wang, S. Li, et al., Chem. Commun. 53 (2017) 4826-4829. doi: 10.1039/C7CC00310B
8. [8]
  Q. Bi, X. Song, A. Hu, et al., Chin. Chem. Lett. 31 (2020) 3041-3046. doi: 10.1016/j.cclet.2020.07.030
9. [9]
  G. Ma, H. Yue, Chin. J. Chem. 38 (2020) 911-923. doi: 10.1002/cjoc.202000135
10. [10]
  G.S. Song, M. Kenney, Y.S. Chen, et al., Nat. Biomed. Eng. 4 (2020) 325. doi: 10.1038/s41551-019-0506-0
11. [11]
  E.J. Kwon, J.S. Dudani, S.N. Bhatia, Nat. Biomed. Eng. 1 (2017) 0054. doi: 10.1038/s41551-017-0054
12. [12]
  J.H. Kang, M. Super, C.W. Yung, et al., Nat. Med. 20 (2014) 1211-1216. doi: 10.1038/nm.3640
13. [13]
  C. Wang, R. Liu, J. Hu, Y. Lv, Chem. Eur. J. 25 (2019) 12270-12274. doi: 10.1002/chem.201903034
14. [14]
  H. Zhao, J. Li, X. Ma, et al., Chin. Chem. Lett. 29 (2018) 102-106. doi: 10.1016/j.cclet.2017.06.013
15. [15]
  H. Xiao, P. Liu, S. Zheng, et al., Chin. Chem. Lett. 31 (2020) 2423-2427. doi: 10.1016/j.cclet.2020.03.003
16. [16]
  W. Shen, X. Lin, C.Y. Jiang, et al., Angew. Chem. Int. Ed. 54 (2015) 7308-7312. doi: 10.1002/anie.201502171
17. [17]
  S. Goggins, C. Naz, B.J. Marsh, C.G. Frost, Chem. Commun. 51 (2015) 561-564. doi: 10.1039/C4CC07693A
18. [18]
  S.A. Hardwick, W.Y. Chen, T. Wong, et al., Nat. Commun. 9 (2018) 10. doi: 10.1038/s41467-017-02449-5
19. [19]
  S. Hume, G.M. Greetham, P.M. Donaldson, et al., Anal. Chem. 92 (2020) 3463-3469. doi: 10.1021/acs.analchem.9b05601
20. [20]
  R. Liu, S. Zhang, C. Wei, et al., Acc. Chem. Res. 49 (2016) 775-783. doi: 10.1021/acs.accounts.5b00509
21. [21]
  C. Ji, Y. Liang, F. Ge, L. Yang, Q. Wang, Anal. Chem. 91 (2019) 7032-7038. doi: 10.1021/acs.analchem.9b01662
22. [22]
  X. Liu, S.Q. Zhang, Z.H. Cheng, et al., Anal. Chem. 90 (2018) 12116-12122. doi: 10.1021/acs.analchem.8b03038
23. [23]
  B. -. R. Li, H. Tang, R.Q. Yu, J. -. H. Jiang, Anal. Chem. 92 (2020) 2379-2382. doi: 10.1021/acs.analchem.9b05741
24. [24]
  G.Y. Xiao, B.B. Chen, M. He, B. Hu, Anal. Chim. Acta 1096 (2020) 18-25. doi: 10.1016/j.aca.2019.10.063
25. [25]
  Y.P. Cao, G.C. Mo, J.S. Feng, et al., Anal. Chim. Acta 1028 (2018) 22-31. doi: 10.1016/j.aca.2018.04.039
26. [26]
  M. Wang, L.N. Zheng, B. Wang, et al., Anal. Chem. 86 (2014) 10252-10256. doi: 10.1021/ac502438n
27. [27]
  S.D. Tanner, D.R. Bandura, O. Ornatsky, et al., Pure Appl. Chem. 80 (2008) 2627-2641. doi: 10.1351/pac200880122627
28. [28]
  Z. Hu, G.W. Sun, W.C. Jiang, et al., Anal. Chem. 91 (2019) 5980-5986. doi: 10.1021/acs.analchem.9b00405
29. [29]
  Q. Zhao, X.F. Lu, C.G. Yuan, X.F. Li, X.C. Le, Anal. Chem. 81 (2009) 7484-7489. doi: 10.1021/ac900961y
30. [30]
  G. Sun, Y. Zhang, Y. Zhang, et al., Talanta 189 (2018) 249-253. doi: 10.1016/j.talanta.2018.07.003
31. [31]
  G.J. Han, S.C. Zhang, Z. Xing, X.R. Zhang, Angew. Chem. Int. Ed. 52 (2013) 1466-1471. doi: 10.1002/anie.201206903
32. [32]
  J. Ko, H.B. Lim, Anal. Chem. 86 (2014) 4140-4144. doi: 10.1021/ac4036668
33. [33]
  H.W. Choi, K.H. Lee, N.H. Hur, H.B. Lim, Anal. Chim. Acta 847 (2014) 10-15. doi: 10.1016/j.aca.2014.08.041
34. [34]
  H. Jang, H.B. Lim, Bull. Korean Chem. Soc. 37 (2016) 1433-1439. doi: 10.1002/bkcs.10884
35. [35]
  X. Lin, W. Guo, L.L. Jin, S.H. Hu, Atom. Spectrosc. 41 (2020) 1-10.
36. [36]
  J.H. Liu, L.N. Zheng, J.W. Shi, et al., Atom. Spectrosc. 42 (2021) 114-119.
37. [37]
  H.R. Tang, H. Wang, C. Yang, et al., Anal. Chem. 92 (2020) 3042-3049. doi: 10.1021/acs.analchem.9b04185
38. [38]
  M.Q. He, K. Wang, W.J. Wang, Y.L. Yu, J.H. Wang, Anal. Chem. 89 (2017) 9292-9298. doi: 10.1021/acs.analchem.7b02073
1. [1]
  Gaowa Xing , Yuting Shang , Xiaorui Wang , Zengnan Wu , Qiang Zhang , Jiebing Ai , Qiaosheng Pu , Ling Lin . A microfluidic biosensor for multiplex immunoassay of foodborne pathogens agitated by programmed audio signals. Chinese Chemical Letters, 2024, 35(10): 109491-. doi: 10.1016/j.cclet.2024.109491
2. [2]
  Meiling Xu , Xinyang Li , Pengyuan Liu , Junjun Liu , Xiao Han , Guodong Chai , Shuangling Zhong , Bai Yang , Liying Cui . A novel and visible ratiometric fluorescence determination of carbaryl based on red emissive carbon dots by a solvent-free method. Chinese Chemical Letters, 2025, 36(2): 109860-. doi: 10.1016/j.cclet.2024.109860
3. [3]
  Simin Wei , Yaqing Yang , Junjie Li , Jialin Wang , Jinlu Tang , Ningning Wang , Zhaohui Li . The Mn/Yb/Er triple-doped CeO₂ nanozyme with enhanced oxidase-like activity for highly sensitive ratiometric detection of nitrite. Chinese Chemical Letters, 2024, 35(6): 109114-. doi: 10.1016/j.cclet.2023.109114
4. [4]
  Ruixin Liu , Feng Shi , Yanping Xia , Haibing Zhu , Jiawen Cao , Kai Peng , Chuanli Ren , Juan Li , Zhanjun Yang . Universal MOF nanozyme-induced catalytic amplification strategy for label-free electrochemical immunoassay. Chinese Chemical Letters, 2024, 35(11): 109664-. doi: 10.1016/j.cclet.2024.109664
5. [5]
  Gengchen Guo , Tianyu Zhao , Ruichang Sun , Mingzhe Song , Hongyu Liu , Sen Wang , Jingwen Li , Jingbin Zeng . Au-Fe₃O₄ dumbbell-like nanoparticles based lateral flow immunoassay for colorimetric and photothermal dual-mode detection of SARS-CoV-2 spike protein. Chinese Chemical Letters, 2024, 35(6): 109198-. doi: 10.1016/j.cclet.2023.109198
6. [6]
  Donghui Wu , Qilin Zhao , Jian Sun , Xiurong Yang . Corrigendum to 'Fluorescence immunoassay based on alkaline phosphatase-induced in situ generation of fluorescent non-conjugated polymer dots' [Chin. Chem. Lett. 34 (2023) 107672]. Chinese Chemical Letters, 2024, 35(12): 109881-. doi: 10.1016/j.cclet.2024.109881
7. [7]
  Tiankai Sun , Hui Min , Zongsu Han , Liang Wang , Peng Cheng , Wei Shi . Rapid detection of nanoplastic particles by a luminescent Tb-based coordination polymer. Chinese Chemical Letters, 2024, 35(5): 108718-. doi: 10.1016/j.cclet.2023.108718
8. [8]
  Huihui LIU , Baichuan ZHAO , Chuanhui WANG , Zhi WANG , Congyun ZHANG . Green synthesis of MIL-101/Au composite particles and their sensitivity to Raman detection of thiram. Chinese Journal of Inorganic Chemistry, 2024, 40(10): 2021-2030. doi: 10.11862/CJIC.20240059
9. [9]
  Xianping Du , Ying Huang , Chen Chen , Zhenhe Feng , Meng Zong . Encapsulating Si particles in multiple carbon shells with pore-rich for constructing free-standing anodes of lithium storage. Chinese Chemical Letters, 2024, 35(12): 109990-. doi: 10.1016/j.cclet.2024.109990
10. [10]
  Jie Wu , Xiaoqing Yu , Guoxing Li , Su Chen . Engineering particles towards 3D supraballs-based passive cooling via grafting CDs onto colloidal photonic crystals. Chinese Chemical Letters, 2024, 35(4): 109234-. doi: 10.1016/j.cclet.2023.109234
11. [11]
  Peng Zhang , Yitao Yang , Tian Qin , Xueqiu Wu , Yuechang Wei , Jing Xiong , Xi Liu , Yu Wang , Zhen Zhao , Jinqing Jiao , Liwei Chen . Interface engineering of Pt/CeO₂-{100} catalysts for enhancing catalytic activity in auto-exhaust carbon particles oxidation. Chinese Chemical Letters, 2025, 36(2): 110396-. doi: 10.1016/j.cclet.2024.110396
12. [12]
  Hongdao LI , Shengjian ZHANG , Hongmei DONG . Magnetic relaxation and luminescent behavior in nitronyl nitroxide-based annuluses of rare-earth ions. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 972-978. doi: 10.11862/CJIC.20230411
13. [13]
  Rui Wang , He Qi , Haijiao Zheng , Qiong Jia . Light/pH dual-responsive magnetic metal-organic frameworks composites for phosphorylated peptide enrichment. Chinese Chemical Letters, 2024, 35(7): 109215-. doi: 10.1016/j.cclet.2023.109215
14. [14]
  Mengyuan Li , Xitong Ren , Yanmei Gao , Mengyao Mu , Shiping Zhu , Shufang Tian , Minghua Lu . Constructing bifunctional magnetic porous poly(divinylbenzene) polymer for high-efficient removal and sensitive detection of bisphenols. Chinese Chemical Letters, 2024, 35(12): 109699-. doi: 10.1016/j.cclet.2024.109699
15. [15]
  Zhao-Bo Hu , Ling-Ao Gui , Long-He Li , Tong-Tong Xiao , Adam T. Hand , Pagnareach Tin , Mykhaylo Ozerov , Yan Peng , Zhongwen Ouyang , Zhenxing Wang , Zi-Ling Xue , You Song . Co^Ⅱ single-ion magnet and its multi-dimensional aggregations: Influence of the structural rigidity on magnetic relaxation process. Chinese Chemical Letters, 2025, 36(2): 109600-. doi: 10.1016/j.cclet.2024.109600
16. [16]
  Xiaoling WANG , Hongwu ZHANG , Daofu LIU . Synthesis, structure, and magnetic property of a cobalt(Ⅱ) complex based on pyridyl-substituted imino nitroxide radical. Chinese Journal of Inorganic Chemistry, 2025, 41(2): 407-412. doi: 10.11862/CJIC.20240214
17. [17]
  Bing Niu , Honggao Huang , Liwei Luo , Li Zhang , Jianbo Tan . Coating colloidal particles with a well-defined polymer layer by surface-initiated photoinduced polymerization-induced self-assembly and the subsequent seeded polymerization. Chinese Chemical Letters, 2025, 36(2): 110431-. doi: 10.1016/j.cclet.2024.110431
18. [18]
  Shuangying Li , Qingxiang Zhou , Zhi Li , Menghua Liu , Yanhui Li . Sensitive measurement of silver ions in environmental water samples integrating magnetic ion-imprinted solid phase extraction and carbon dot fluorescent sensor. Chinese Chemical Letters, 2024, 35(5): 108693-. doi: 10.1016/j.cclet.2023.108693
19. [19]
  Yan Cheng , Hua-Peng Ruan , Yan Peng , Longhe Li , Zhenqiang Xie , Lang Liu , Shiyong Zhang , Hengyun Ye , Zhao-Bo Hu . Magnetic, dielectric and luminescence synergetic switchable effects in molecular material [Et₃NCH₂Cl]₂[MnBr₄]. Chinese Chemical Letters, 2024, 35(4): 108554-. doi: 10.1016/j.cclet.2023.108554
20. [20]
  Guang-Xu Duan , Queting Chen , Rui-Rui Shao , Hui-Huang Sun , Tong Yuan , Dong-Hao Zhang . Encapsulating lipase on the surface of magnetic ZIF-8 nanosphers with mesoporous SiO₂ nano-membrane for enhancing catalytic performance. Chinese Chemical Letters, 2025, 36(2): 109751-. doi: 10.1016/j.cclet.2024.109751

Get Citation

PDF

XML

Metrics

PDF Downloads(1)
Abstract views(518)
HTML views(55)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142