Citation: Xiaoqian Jiang, Chenfang Sun, Congcong Zhang, Shanshan Cheng. Highly responsive biosensors based on organic field-effect transistors under light irradiation[J]. Chinese Chemical Letters, ;2021, 32(11): 3364-3367. doi: 10.1016/j.cclet.2021.04.005 shu

Highly responsive biosensors based on organic field-effect transistors under light irradiation

a.
Department of Chemistry, Tianjin Key Laboratory of Molecular Optoelectronic Sciences School of Science, Tianjin University, Tianjin 300072, China
b.
Institute for Advanced Interdisciplinary Research, University of Jinan, Jinan 250011, China

chengss@tju.edu.cn

Received Date: 1 February 2021
Revised Date: 28 February 2021
Accepted Date: 1 April 2021
Available Online: 3 April 2021

Figures(4)

High responsivity and sensitivity play essential roles in the development of organic field-effect transistors (OFETs)-based biosensors with regard to biological detections, particularly for disease diagnosis. Nonetheless, how to design a biosensor which improves these two outstanding properties while achieving low cost, easy processing, and time saving is a daunting challenge. Herein, a novel biosensor based on OFET with copolymer thin film, whose surface is illuminated with a suitable light beam is reported. This film can be used as both an organic semiconductor material and as a photoelectric active material. Due to amplification of signals as a result of the film's strong response to light, the biosensor possesses higher responsivity and sensitivity compared to dark condition and even realizes a maximum responsivity of up to 10³ for alpha-fetoprotein (AFP) detection. The simple combination of light and transistor builds a bridge between photoelectric effect and biological system. In addition, the emergence of more excellent photoelectric active materials is expected to pave a way for ultrasensitive bio-chemical diagnostic tools.
- Organic field-effect transistors,
- Photoelectric active materials,
- Photo response,
- Biosensors,
- Disease diagnosis
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1.
沈阳化工大学材料科学与工程学院沈阳 110142