Citation: Xiao-Qiao Hong, Yuan-Yuan Xing, Zhong-Kun Wang, Qin-Chao Mao, Wen-Hua Chen. Curvature-regulated transmembrane anion transport by a trifluoromethylated bisbenzimidazole[J]. Chinese Chemical Letters, ;2021, 32(5): 1653-1656. doi: 10.1016/j.cclet.2021.01.005 shu

Curvature-regulated transmembrane anion transport by a trifluoromethylated bisbenzimidazole

a.
School of Biotechnology and Health Sciences, Wuyi University, Jiangmen 529020, China
b.
School of Pharmaceutical Sciences, Tsinghua University, Beijing 100084, China
c.
Guangdong Maoming Health Vocational College, Maoming 525000, China
d.
State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, Peking University Shenzhen Graduate School, Shenzhen 518055, China

Received Date: 25 November 2020
Revised Date: 18 December 2020
Accepted Date: 4 January 2021
Available Online: 9 January 2021

Figures(6)

In this paper, we demonstrate that modification of anion-transport active 1, 3-bis(benzimidazol-2-yl) benzene with strongly electron-withdrawing trifluoromethyl and nitro groups leads to a dramatic increase in the anionophoric activity, and the activity may be greatly regulated by the curvatures of the liposomes used.
- Anion transporter,
- Lysosomal curvature,
- Anionophoric activity
1. [1]
  J.T. Davis, P.A. Gale, R. Quesada, Chem. Soc. Rev. 49(2020) 6056-6086. doi: 10.1039/C9CS00662A
2. [2]
  X.H. Yu, X.Q. Hong, Q.C. Mao, W.H. Chen, Eur. J. Med. Chem. 184(2019) 111782. doi: 10.1016/j.ejmech.2019.111782
3. [3]
  P.A. Gale, J.T. Davis, R. Quesada, Chem. Soc. Rev. 46(2017) 2497-2519. doi: 10.1039/C7CS00159B
4. [4]
  N. Busschaert, A.P. Gale, Angew. Chem. Int. Ed. 52(2013) 1374-1382. doi: 10.1002/anie.201207535
5. [5]
  S. Zhang, I. Boussouar, H. Li, Chin. Chem. Lett. 32(2021) 642-648. doi: 10.1016/j.cclet.2020.06.035
6. [6]
  N. Busschaert, S.H. Park, K.H. Baek, et al., Nat. Chem. 9(2017) 667-675. doi: 10.1038/nchem.2706
7. [7]
  I. Alfonso, R. Quesada, Chem. Sci. 4(2013) 3009-3019. doi: 10.1039/c3sc50882j
8. [8]
  J.L. Sessler, L.R. Eller, W.S. Cho, et al., Angew. Chem. Int. Ed. 44(2005) 5989-5992. doi: 10.1002/anie.200501740
9. [9]
  M. Mehiri, W.H. Chen, V. Janout, S.L. Regen, J. Am. Chem. Soc. 131(2009)1338-1339. doi: 10.1021/ja806476t
10. [10]
  M.J. Spooner, P.A. Gale, Chem. Commun. 51(2015) 4883-4886. doi: 10.1039/C5CC00823A
11. [11]
  H. Mitomo, W.H. Chen, S.L. Regen, Langmuir 25(2009) 4328-4330. doi: 10.1021/la900346p
12. [12]
  C.C. Peng, Z. Li, L.Q. Deng, Z.F. Ke, W.H. Chen, Bioorg. Med. Chem. Lett. 26(2016) 2442-2445. doi: 10.1016/j.bmcl.2016.03.114
13. [13]
  C.C. Peng, M.J. Zhang, X.X. Sun, et al., Org. Biomol. Chem. 14(2016) 8232-8236. doi: 10.1039/C6OB01461E
14. [14]
  X.H. Yu, C.C. Peng, X.X. Sun, W.H. Chen, Eur. J. Med. Chem. 152(2018) 115-125. doi: 10.1016/j.ejmech.2018.04.036
15. [15]
  X.H. Yu, X.Q. Hong, W.H. Chen, Org. Biomol. Chem. 17(2019) 1558-1571. doi: 10.1039/C8OB03036G
16. [16]
  A. Company, L. Gomez, R. Mas-Balleste, et al., Inorg. Chem. 46(2007) 4997-5012. doi: 10.1021/ic0701108
17. [17]
  H. Valkenier, C.M. Dias, K.L.P. Goff, et al., Chem. Commun. 51(2015) 14235-14238. doi: 10.1039/C5CC05737J
18. [18]
  S.J. Moore, M. Wenzel, M.E. Light, et al., Chem. Sci. 3(2012) 2501-2509. doi: 10.1039/c2sc20551c
19. [19]
  V. Saggiomo, S. Otto, I. Marques, et al., Chem. Commun. 48(2012) 5274-5276. doi: 10.1039/c2cc31825c
20. [20]
  Z. Li, Y. Chen, D.Q. Yuan, W.H. Chen, Org. Biomol. Chem. 15(2017) 2831-2840. doi: 10.1039/C7OB00289K
21. [21]
  H. Valkenier, C.J.E. Haynes, J. Herniman, P.A. Gale, A.P. Davis, Chem. Sci. 5(2014) 1128-1134. doi: 10.1039/c3sc52962b
22. [22]
  P.A. Gale, C.C. Tong, C.J.E. Haynes, et al., J. Am. Chem. Soc. 132(2010) 3240-3241. doi: 10.1021/ja9092693
23. [23]
  Z. Li, X.H. Yu, Y. Chen, D.Q. Yuan, W.H. Chen, J. Org. Chem. 82(2017)13368-13375. doi: 10.1021/acs.joc.7b02447
24. [24]
  T. Saha, M.S. Hossain, D. Saha, M. Lahiri, P. Talukdar, J. Am. Chem. Soc. 138(2016) 7558-7567. doi: 10.1021/jacs.6b01723
25. [25]
  G.W. Gokel, A. Mukhopadhyay, Chem. Soc. Rev. 30(2001) 274-286. doi: 10.1039/b008667n
26. [26]
  J. Zhou, A. Kulasinghe, A. Bogseth, et al., Microsyst. Nanoeng. 5(2019) 8. doi: 10.1038/s41378-019-0045-6
1. [1]
  Yunjia Jiang , Lingyao Wang , Yuanbin Zhang . Anion pillared MOFs for challenging hydrocarbon separations. Chinese Journal of Structural Chemistry, 2024, 43(11): 100374-100374. doi: 10.1016/j.cjsc.2024.100374
2. [2]
  Jiao Chen , Zihan Zhang , Guojin Sun , Yudi Cheng , Aihua Wu , Zefan Wang , Wenwen Jiang , Fulin Chen , Xiuying Xie , Jianli Li . Benzo[4,5]imidazo[1,2-a]pyrimidine-based structure-inherent targeting fluorescent sensor for imaging lysosomal viscosity and diagnosis of lysosomal storage disorders. Chinese Chemical Letters, 2024, 35(11): 110050-. doi: 10.1016/j.cclet.2024.110050
3. [3]
  Guangyao Wang , Zhitong Xu , Ye Qi , Yueguang Fang , Guiling Ning , Junwei Ye . Electrospun nanofibrous membranes with antimicrobial activity for air filtration. Chinese Chemical Letters, 2024, 35(10): 109503-. doi: 10.1016/j.cclet.2024.109503
4. [4]
  Jing JIN , Zhuming GUO , Zhiyin XIAO , Xiujuan JIANG , Yi HE , Xiaoming LIU . Tuning the stability and cytotoxicity of fac-[Fe(CO)₃I₃]^- anion by its counter ions: From aminiums to inorganic cations. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 991-1004. doi: 10.11862/CJIC.20230458
5. [5]
  Hong-Jin Liao , Zhu Zhuo , Qing Li , Yoshihito Shiota , Jonathan P. Hill , Katsuhiko Ariga , Zi-Xiu Lu , Lu-Yao Liu , Zi-Ang Nan , Wei Wang , You-Gui Huang . A new class of crystalline X-ray induced photochromic materials assembled from anion-directed folding of a flexible cation. Chinese Chemical Letters, 2024, 35(8): 109052-. doi: 10.1016/j.cclet.2023.109052
6. [6]
  Pu Zhang , Xiang Mao , Xuehua Dong , Ling Huang , Liling Cao , Daojiang Gao , Guohong Zou . Two UV organic-inorganic hybrid antimony-based materials with superior optical performance derived from cation-anion synergetic interactions. Chinese Chemical Letters, 2024, 35(9): 109235-. doi: 10.1016/j.cclet.2023.109235
7. [7]
  Jingtai Bi , Yupeng Cheng , Mengmeng Sun , Xiaofu Guo , Shizhao Wang , Yingying Zhao . Efficient and selective photocatalytic nitrite reduction to N₂ through CO₂ anion radical by eco-friendly tartaric acid activation. Chinese Chemical Letters, 2024, 35(11): 109639-. doi: 10.1016/j.cclet.2024.109639
8. [8]
  Ting Wang , Xin Yu , Yaqiang Xie . Unlocking stability: Preserving activity of biomimetic catalysts with covalent organic framework cladding. Chinese Chemical Letters, 2024, 35(6): 109320-. doi: 10.1016/j.cclet.2023.109320
9. [9]
  Fangping Yang , Jin Shi , Yuansong Wei , Qing Gao , Jingrui Shen , Lichen Yin , Haoyu Tang . Mixed-charge glycopolypeptides as antibacterial coatings with long-term activity. Chinese Chemical Letters, 2025, 36(2): 109746-. doi: 10.1016/j.cclet.2024.109746
10. [10]
  Chong Liu , Ling Li , Jiahui Gao , Yanwei Li , Nazhen Zhang , Jing Zang , Cong Liu , Zhaopei Guo , Yanhui Li , Huayu Tian . The study of antibacterial activity of cationic poly(β-amino ester) regulating by amphiphilic balance. Chinese Chemical Letters, 2025, 36(2): 110118-. doi: 10.1016/j.cclet.2024.110118
11. [11]
  Xiangyuan Zhao , Jinjin Wang , Jinzhao Kang , Xiaomei Wang , Hong Yu , Cheng-Feng Du . Ni nanoparticles anchoring on vacuum treated Mo2TiC2Tx MXene for enhanced hydrogen evolution activity. Chinese Journal of Structural Chemistry, 2023, 42(10): 100159-100159. doi: 10.1016/j.cjsc.2023.100159
12. [12]
  Xinyi Hu , Riguang Zhang , Zhao Jiang . Depositing the PtNi nanoparticles on niobium oxide to enhance the activity and CO-tolerance for alkaline methanol electrooxidation. Chinese Journal of Structural Chemistry, 2023, 42(11): 100157-100157. doi: 10.1016/j.cjsc.2023.100157
13. [13]
  Anqiu LIU , Long LIN , Dezhi ZHANG , Junyu LEI , Kefeng WANG , Wei ZHANG , Junpeng ZHUANG , Haijun HAO . Synthesis, structures, and catalytic activity of aluminum and zinc complexes chelated by 2-((2,6-dimethylphenyl)amino)ethanolate. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 791-798. doi: 10.11862/CJIC.20230424
14. [14]
  Bin Dong , Ning Yu , Qiu-Yue Wang , Jing-Ke Ren , Xin-Yu Zhang , Zhi-Jie Zhang , Ruo-Yao Fan , Da-Peng Liu , Yong-Ming Chai . Double active sites promoting hydrogen evolution activity and stability of CoRuOH/Co₂P by rapid hydrolysis. Chinese Chemical Letters, 2024, 35(7): 109221-. doi: 10.1016/j.cclet.2023.109221
15. [15]
  Tao Yu , Vadim A. Soloshonok , Zhekai Xiao , Hong Liu , Jiang Wang . Probing the dynamic thermodynamic resolution and biological activity of Cu(Ⅱ) and Pd(Ⅱ) complexes with Schiff base ligand derived from proline. Chinese Chemical Letters, 2024, 35(4): 108901-. doi: 10.1016/j.cclet.2023.108901
16. [16]
  Jia Chen , Yun Liu , Zerong Long , Yan Li , Hongdeng Qiu . Colorimetric detection of α-glucosidase activity using Ni-CeO₂ nanorods and its application to potential natural inhibitor screening. Chinese Chemical Letters, 2024, 35(9): 109463-. doi: 10.1016/j.cclet.2023.109463
17. [17]
  Guoping Yang , Zhoufu Lin , Xize Zhang , Jiawei Cao , Xuejiao Chen , Yufeng Liu , Xiaoling Lin , Ke Li . Assembly of Y(Ⅲ)-containing antimonotungstates induced by malic acid with catalytic activity for the synthesis of imidazoles. Chinese Chemical Letters, 2024, 35(12): 110274-. doi: 10.1016/j.cclet.2024.110274
18. [18]
  Meng Wang , Yan Zhang , Yunbo Yu , Wenpo Shan , Hong He . High-temperature calcination dramatically promotes the activity of Cs/Co/Ce-Sn catalyst for soot oxidation. Chinese Chemical Letters, 2025, 36(1): 109928-. doi: 10.1016/j.cclet.2024.109928
19. [19]
  Yao HUANG , Yingshu WU , Zhichun BAO , Yue HUANG , Shangfeng TANG , Ruixue LIU , Yancheng LIU , Hong LIANG . Copper complexes of anthrahydrazone bearing pyridyl side chain: Synthesis, crystal structure, anticancer activity, and DNA binding. Chinese Journal of Inorganic Chemistry, 2025, 41(1): 213-224. doi: 10.11862/CJIC.20240359
20. [20]
  Guo-Ping Yin , Ya-Juan Li , Li Zhang , Ling-Gao Zeng , Xue-Mei Liu , Chang-Hua Hu . Citrinsorbicillin A, a novel homotrimeric sorbicillinoid isolated by LC-MS-guided with cytotoxic activity from the fungus Trichoderma citrinoviride HT-9. Chinese Chemical Letters, 2024, 35(8): 109035-. doi: 10.1016/j.cclet.2023.109035

Get Citation

PDF

XML

Metrics

PDF Downloads(5)
Abstract views(678)
HTML views(93)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142