Citation: Ke Yang, Yi Li, Mengjie Song, Shengfei Dai, Zheng-Yi Li, Xiaoqiang Sun. Metal-free direct C(sp³)—H functionalization of 2-alkylthiobenzoic acid to access 1, 3-benzooxathiin-4-one[J]. Chinese Chemical Letters, ;2021, 32(1): 146-149. doi: 10.1016/j.cclet.2020.11.036 shu

Metal-free direct C(sp³)—H functionalization of 2-alkylthiobenzoic acid to access 1, 3-benzooxathiin-4-one

Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, School of Petrochemical Engineering, Changzhou University, Changzhou 213164, China

keyang@cczu.edu.cn

zyli@cczu.edu.cn

Received Date: 25 September 2020
Revised Date: 9 November 2020
Accepted Date: 11 November 2020
Available Online: 23 November 2020

Figures(7)

Metal-free direct α-C(sp³)—H intramolecular cyclization of 2-alkylthiobenzoic acid in the presence of Selectfluor is described. This novel strategy provides a facile and efficient method to access important 1, 3-benzooxathiin-4-one derivatives with good functional groups tolerance and yields.
- Metal-free,
- C(sp³)—H functionalization,
- Selectfluor,
- 1, 3-Benzooxathiin-4-one,
- Organic synthesis
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Metal-free direct C(sp3)—H functionalization of 2-alkylthiobenzoic acid to access 1, 3-benzooxathiin-4-one

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通讯作者: 陈斌, bchen63@163.com

Metal-free direct C(sp³)—H functionalization of 2-alkylthiobenzoic acid to access 1, 3-benzooxathiin-4-one