Citation: Liu Kai-Jian, Deng Ji-Hui, Zeng Tang-Yu, Chen Xin-Jie, Huang Ying, Cao Zhong, Lin Ying-Wu, He Wei-Min. 1, 2-Diethoxyethane catalyzed oxidative cleavage of gem-disubstituted aromatic alkenes to ketones under minimal solvent conditions[J]. Chinese Chemical Letters, ;2020, 31(7): 1868-1872. doi: 10.1016/j.cclet.2020.01.036 shu

1, 2-Diethoxyethane catalyzed oxidative cleavage of gem-disubstituted aromatic alkenes to ketones under minimal solvent conditions

a.
Department of Chemistry, Hunan University of Science and Engineering, Yongzhou 425100, China
b.
Hunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation, Changsha University of Science and Technology, Changsha 410114, China
c.
School of Chemistry and Chemical Engineering, Hunan University of Science and Technology, Xiangtan 411201, China
d.
School of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, China

weiminhe2016@yeah.net

Received Date: 21 November 2019
Revised Date: 1 January 2020
Accepted Date: 17 January 2020
Available Online: 17 January 2020

Figures(7)

Aerobic oxidation using pure dioxygen gas as the oxidant has attracted much attention, but its application in synthetic chemistry has been significantly hampered by the complexity of catalytic system and potential risk of high-energy dioxygen gas. By employing 1, 2-diethoxyethane as a catalyst and ambient air as an oxidant, an efficient protocol for the construction of various aryl-alkyl and diaryl ketones through oxidative cleavage of gem-disubstituted aromatic alkenes under minimal solvent conditions has been achieved.
- Ketone,
- Oxidation,
- Ambient air,
- Oxidative cleavage
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