Citation: Xu Fu-Jian. Deciphering the impact of PEG antifouling layer on surface attached functional peptides in regulating cell behaviors[J]. Chinese Chemical Letters, ;2019, 30(12): 2051-2052. doi: 10.1016/j.cclet.2019.10.038 shu

Deciphering the impact of PEG antifouling layer on surface attached functional peptides in regulating cell behaviors

Xu Fu-Jian

Key Lab of Biomedical Materials of Natural Macromolecules, Beijing University of Chemical Technology, Ministry of Education. State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing Laboratory of Biomedical Materials, Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China

xufj@mail.buct.edu.cn

Received Date: 14 October 2019
Revised Date: 25 October 2019
Accepted Date: 25 October 2019
Available Online: 2 December 2019

Figures(1)

It is highly desired to have bioactive surfaces for biomaterials and controllable interactions with cells. These functions were widely achieved by attaching functional peptides to the surface of biomaterials. It is well known that an antifouling layer can help reducing the nonspecific cell attachment. However, it is unclear how an antifouling PEG layer affects the function of peptides attached on material surface in controlling cell behavior. This highlight introduced the recent JACS paper from Prof. Liu and coworkers in addressing this question thoroughly.
- Antifouling,
- PEG,
- Biomaterials,
- Surface modification,
- Cell behaviors
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