Citation: Han Xiang-Lei, Lin Peng-Peng, Li Qingjiang. Recent advances of allenes in the first-row transition metals catalyzed C—H activation reactions[J]. Chinese Chemical Letters, ;2019, 30(8): 1495-1502. doi: 10.1016/j.cclet.2019.04.027 shu

Recent advances of allenes in the first-row transition metals catalyzed C—H activation reactions

a.
School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China
b.
State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China

Author Bio:

Qingjiang Li was born in Anhui, China in 1985. He received his Bachelor degree in 2007 from Lanzhou University. Then he moved to Peking University and obtained his Ph.D. under the guidance of Prof. Yanxing Jia. After two years as a research assistant in Prof. Henry N.C. Wong's lab at the Chinese University of Hong Kong, he was appointed as an associate professor at Sun Yat-sen University in 2014. His current research interests are the metal-catalyzed C–H functionalization reactions, the development of novel reactions for organic synthesis, and total synthesis of natural products

liqingj3@mail.sysu.edu.cn

Received Date: 30 January 2019
Revised Date: 26 March 2019
Accepted Date: 9 April 2019
Available Online: 16 August 2019

Figures(20)

Transition-metal-catalyzed C–H activation reaction has proven to be a powerful and efficient tool for the formation of diverse C–C and C–X bond and construction of functional complex molecules. From the viewpoint of sustainable chemistry, the first-row transition metals, such as Mn, Fe, Co, Ni and Cu, have been recognized as cheap, environmentally friendly and reactively effective catalysts for a number of C–H functionalization reactions. However, compared with the commonly used alkenes and alkynes in the first-row transition-metal-catalyzed C–H activations, considerable achievements have just been made by the use of structurally unique and reactively rich allenes as coupling partners in recent years. This review summarizes the recent progress of the first-row transition-metal-catalyzed C–H activations with allenes.
- Allene,
- C-H functionalization,
- First-row transition metal,
- Annulation,
- Regioselectivity
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