Citation: Wang Yuzhen, Song Yujun, Zhu Guixian, Zhang Dechen, Liu Xuewu. Highly biocompatible BSA-MnO₂ nanoparticles as an efficient near-infrared photothermal agent for cancer therapy[J]. Chinese Chemical Letters, ;2018, 29(11): 1685-1688. doi: 10.1016/j.cclet.2017.12.004 shu

Highly biocompatible BSA-MnO₂ nanoparticles as an efficient near-infrared photothermal agent for cancer therapy

a.
Key Laboratory of Flexible Electronics(KLOFE) & Institute of Advanced Materials(IAM), Jiangsu National Synergistic Innovation Center for Advanced Materials(SICAM), Nanjing Tech University(NanjingTech), Nanjing 211816, China
b.
Department of Biomedical Engineering, College of Engineering and Applied Sciences, Nanjing University, Nanjing 210093, China
c.
Department of Nanomedicine, Houston Methodist Research Institute, Houston TX 77030, United States

Corresponding author: Song Yujun, ysong@nju.edu.cn Liu Xuewu, xliu@houstonmethodist.org
Received Date: 23 October 2017
Revised Date: 21 November 2017
Accepted Date: 4 December 2017
Available Online: 7 November 2017

Figures(4)

More recently, the biomedical applications of MnO₂ in bioanalysis, cell imaging, and drug delivery as a result of their appealing physicochemical properties, have been reported and expanded rapidly. However, research on a near infrared (NIR) photothermal response of MnO₂ was ignored. In this work, we reported a facile, one-pot method to synthesis of bovine serum albumin (BSA)-reduced and stabilized MnO₂ nanoparticles (BSA-MnO₂ NPs) with good aqueous dispersibility and high biocompatibility. And we also showed for the first time that BSA-MnO₂ NPs displayed superior NIR photothermal efficiency and photostability which demonstrated as a novel class of photothermal antitumor agent.
- Bovine serum albumin,
- Manganese dioxide,
- Photothermal,
- NIR,
- Cancer therapy
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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Highly biocompatible BSA-MnO2 nanoparticles as an efficient near-infrared photothermal agent for cancer therapy

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通讯作者: 陈斌, bchen63@163.com

Highly biocompatible BSA-MnO₂ nanoparticles as an efficient near-infrared photothermal agent for cancer therapy