Citation: Xu Jian, Kuang Zhijie, Song Qiuling. Expedient chemoselective and catalyst-free synthesis of 3, 3-difluorochroman-4-ones from o-hydroxyarylenaminones and Selectfluor[J]. Chinese Chemical Letters, ;2018, 29(6): 963-966. doi: 10.1016/j.cclet.2017.10.027 shu

Expedient chemoselective and catalyst-free synthesis of 3, 3-difluorochroman-4-ones from o-hydroxyarylenaminones and Selectfluor

Institute of Next Generation Matter Transformation, College of Chemical Engineering at Huaqiao University, Xiamen 361021, China

Corresponding author: Song Qiuling, qsong2002@gmail.com; qsong@hqu.edu.cn

Received Date: 5 September 2017
Revised Date: 2 October 2017
Accepted Date: 23 October 2017
Available Online: 28 June 2017

Figures(7)

An expedient and mild strategy for the synthesis of unconventional 2-(dimethylamino)-3, 3-difluorochroman-4-one derivatives from o-hydroxyarylenaminones and Selectfluor was developed at room temperature under catalyst-free conditions. This method showed excellent chemoselectivity and great functional groups tolerance.
- Selectfluor,
- o-Hydroxyarylenaminones,
- Catalyst-free,
- Chroman-4-one,
- Fluorination reaction,
- Fluorine-contained compound
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沈阳化工大学材料科学与工程学院沈阳 110142