Citation: Wang Haibo, Pan Yang, Tang Qin, Zou Wei, Shao Huawu. Synthesis of N-alkyl substituted iminosugars from _D-ribose[J]. Chinese Chemical Letters, ;2018, 29(1): 73-75. doi: 10.1016/j.cclet.2017.10.004 shu

Synthesis of N-alkyl substituted iminosugars from _D-ribose

Wang Haibo ^a,c,d ,
Pan Yang ^a,d ,
Tang Qin ^a,d ,
Zou Wei ^b ,
Shao Huawu ^a,,

a.
Natural Products Research Center, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China
b.
Institute for Biological Sciences, National Research Council of Canada, Ottawa K1A 0R6, Canada
c.
Zhejiang Hongyuan Pharmaceutical Co., Ltd., Linhai 317000, China
d.
Graduate School of Chinese Academy of Sciences, Beijing 100049, China

Corresponding author: Shao Huawu, shaohw@cib.ac.cn
Received Date: 30 June 2017
Revised Date: 8 September 2017
Accepted Date: 10 October 2017
Available Online: 16 January 2017

Figures(4)

An effective and facile method for the synthesis of N-alkylated hydroxylpyrrolidine and hydroxylpiperidine is described. A number of N-alkyl substituted iminosugars were prepared using iodine-induced intramolecular cyclization of acyclic alkenylamines as key step.
- Iminosugar,
- Pyrrolidine,
- Piperidine,
- Glycosidase,
- D-Ribose
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沈阳化工大学材料科学与工程学院沈阳 110142

Synthesis of N-alkyl substituted iminosugars from D-ribose

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通讯作者: 陈斌, bchen63@163.com

Synthesis of N-alkyl substituted iminosugars from _D-ribose