Citation: Chu Mei-Jun, Tang Xu-Li, Qin Guo-Fei, de Voogd Nicole J., Li Ping-Lin, Li Guo-Qiang. Three new non-brominated pyrrole alkaloids from the South China Sea sponge Agelas nakamurai[J]. Chinese Chemical Letters, ;2017, 28(6): 1210-1213. doi: 10.1016/j.cclet.2017.01.009 shu

Three new non-brominated pyrrole alkaloids from the South China Sea sponge Agelas nakamurai

Chu Mei-Jun ^a,b,1 ,
Tang Xu-Li ^c,1 ,
Qin Guo-Fei ^a,b ,
de Voogd Nicole J. ^d ,
Li Ping-Lin ^a,b,, ,
Li Guo-Qiang ^a,b,,

a.
Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China
b.
Laboratory of Marine Drugs and Biological Products, National Laboratory for Marine Science and Technology, Qingdao 266235, China
c.
College of Chemistry and Chemical Engineering, Ocean University of China, Qingdao 266100, China dNational Museum of Natural History, 2300 RA Leiden, The Netherlands
d.
National Museum of Natural History, 2300 RA Leiden, The Netherlands

Corresponding author: Li Ping-Lin, lipinglin@ouc.edu.cn Li Guo-Qiang, liguoqiang@ouc.edu.cn

Received Date: 8 October 2016
Revised Date: 2 December 2016
Accepted Date: 27 December 2016
Available Online: 12 June 2017

Figures(2)

Three new non-brominated pyrrole alkaloids, nakamurines A-C (1-3) were isolated from the South China Sea sponge Agelas nakamurai. Their structures were elucidated on the basis of spectroscopic data. Compound 2 showed weak antimicrobial activity against Candida albicans with MIC of 60 μg/mL.
- Marine sponge,
- The South China Sea,
- Agelas nakamurai,
- Pyrrole alkaloids,
- Antimicrobial
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