Citation: Jin-Peng Li, Chang-Chun Yuan, Biao Du, Bo Liu. An alternative total synthesis of bolivianine[J]. Chinese Chemical Letters, ;2017, 28(1): 113-116. doi: 10.1016/j.cclet.2016.06.013 shu

An alternative total synthesis of bolivianine

Key Laboratory of Green Chemistry & Technology of Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, China

Corresponding author: Bo Liu, chembliu@scu.edu.cn
Received Date: 28 April 2016
Revised Date: 19 May 2016
Accepted Date: 25 May 2016
Available Online: 11 January 2016

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An alternative total synthesis of bolivianine in twelve steps is herein reported on the basis of our previous successful bioinspired total synthesis. The present total synthesis features straightforward transformation from an aldol product to the butenolide of the target molecule, and stereoselective DielsAlder cycloaddition to construct ring E, as well as the final spontaneous IMHDA process.
- Total synthesis,
- Cyclopropanation,
- Aldol,
- Diels-Alder,
- Terpeniod
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