Citation: Zhao Zheng-Le, Gu Qing, Wu Xin-Yan, You Shu-Li. Enantioselective synthesis of 10-allylanthrones via iridium-catalyzed allylic substitution reaction[J]. Chinese Chemical Letters, ;2016, 27(5): 619-622. doi: 10.1016/j.cclet.2016.02.017 shu

Enantioselective synthesis of 10-allylanthrones via iridium-catalyzed allylic substitution reaction

Zhao Zheng-Le ^a,b ,
Gu Qing ^b ,
Wu Xin-Yan ^a,, ,
You Shu-Li ^a,b,,

a.
Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology, Shanghai 200237, China
b.
State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China

Corresponding author: Wu Xin-Yan, xinyanwu@ecust.edu.cn You Shu-Li, slyou@sioc.ac.cn
Received Date: 26 January 2016
Revised Date: 18 February 2016
Accepted Date: 19 February 2016
Available Online: 2 May 2016

Figures(2)

A highly enantioselective allylic substitution reaction of anthrones with aromatic or aliphatic allyl carbonates was realized by using iridium catalyst prepared from [Ir(COD)Cl]₂ and BHPphos. Substituted 10-allylanthrones were obtained in excellent yields and with excellent enantioselectivity and regioselectivity (up to 98% yield, 99% ee) under mild conditions.
- Allylic substitution,
- Anthrone,
- Asymmetric catalysis,
- Enantioselectivity,
- Iridium
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