Citation: Jian-Guo Yang, Ling-Zhen Xu, Ling Huang, Jian-Rong Gao, Miao-Chang Liu, Fu-You Pan, Ding-Ben Chen. Iron-catalyzed synthesis of polycyclic-fused azo[l,2-a]indolones via an SNAr/acylation cascade reactions[J]. Chinese Chemical Letters, ;2016, 27(03): 340-344. doi: 10.1016/j.cclet.2015.11.005
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An efficient method has been developed for the cascade synthesis of azo[l,2-a]indolones from azoles and 2-fluoroaldehydes based on an iron-catalyzed SNAr and a direct acylation reaction. A number of azo[l,2-a] indolones containing different azole rings and substituents were obtained in good yields.
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Keywords:
- Iron,
- Cyclization,
- Cascade reaction,
- Azo[l,2-a]indol-ones,
- Direct acylation
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