Citation: Hemal B. Mehta, Bharat C. Dixit, Ritu B. Dixit. L-Proline catalyzed one-pot multi-component synthesis of 2-(1, 3-diphenyl-1H-pyrazol-4-yl)quinazolin-4(3H)-one derivatives and their biological studies[J]. Chinese Chemical Letters, ;2014, 25(05): 741-744. doi: 10.1016/j.cclet.2014.03.015 shu

L-Proline catalyzed one-pot multi-component synthesis of 2-(1, 3-diphenyl-1H-pyrazol-4-yl)quinazolin-4(3H)-one derivatives and their biological studies

1.
a Ashok and Rita Patel Institute of Integrated Study and Research in Biotechnology and Allied Sciences, New Vallabh Vidyanagar 388121, India;
b Chemistry Departments, V.
b Chemistry Departments, V. P. and R. P. T. P Science College, Affiliated to Sardar Patel University, Vallabh Vidyanagar 388120, India

Corresponding author: Ritu B. Dixit,
Received Date: 11 September 2013
Available Online: 18 February 2014

A new series of quinazolin-4(3H)-one derivatives containing a (1,3-diphenyl-1H-pyrazol-4-yl) core with substituents at the 2-position and aromatic or heteroaromatic substituents at the 3-position were synthesized using an L-proline catalyzed one-pot multi-component reaction approach. All the synthesized compounds were characterized and screened for their antimicrobial, antifungal and anti-tubercular activities.
- Quinazolin-4(3H)-one,
- Pyrazole,
- L-Proline,
- Antimicrobial,
- Antifungal,
- Anti-tubercular activity
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