Citation: Javad Safaei-Ghomi, Hossein Shahbazi-Alavi, Abolfazl Ziarati, Raheleh Teymuri, Mohammad Reza Saberi. A highly flexible green synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives with CuI nanoparticles as catalyst under solvent-free conditions[J]. Chinese Chemical Letters, ;2014, 25(3): 401-405. doi: 10.1016/j.cclet.2013.11.046 shu

A highly flexible green synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives with CuI nanoparticles as catalyst under solvent-free conditions

1.
Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan 51167, Iran

Corresponding author: Javad Safaei-Ghomi,
Received Date: 13 August 2013
Available Online: 13 November 2013
Fund Project: The authors are grateful to University of Kashan for supporting this work (No. 159196/XⅡV). (No. 159196/XⅡV)

CuI nanoparticles as an efficient catalyst have been used for the preparation of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones by the four-component condensation reaction of phthalic anhydride, hydrazine monohydrate, aromatic aldehydes and malononitrile or ethyl cyanoacetate under solventfree conditions in good to excellent yields, short reaction times and environmentally benign, milder reaction conditions.
- Nanoparticles,
- Multi-component reactions,
- Solvent-free,
- Pyrazolophthalazine
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