Citation: Ning Ning Wan, Yong Lei Yang, Wen Ping Wang, Zheng Feng Xie, Ji De Wang. Friedel-Crafts alkylation of indoles with nitroalkenes catalyzed by Cu(Ⅱ)-imine complex[J]. Chinese Chemical Letters, ;2011, 22(10): 1155-1158. doi: 10.1016/j.cclet.2011.04.013 shu

Friedel-Crafts alkylation of indoles with nitroalkenes catalyzed by Cu(Ⅱ)-imine complex

a College of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046, China;
b Key Laboratory of Oil & Gas Fine Chemicals of Ministry of Education, Xinjiang University, Urumqi 830046, China

Received Date: 11 January 2011

Fund Project: We appreciate the financial support from the National Natural Science Foundation of China (Nos.20962018, 20862015, 20762009 and 20562011).

A series of new ligands L₁-L₇ were readily prepared in one step. Friedel-Crafts alkylation of indoles with nitroalkenes catalyzed by a novel Cu (Ⅱ)-L complex has been developed. The remarkable advantages of this reaction are mild reaction conditions, simple workup procedure, high yields of products and the use of ethanol as a green solvent.
- Friedel-Crafts alkylation,
- Indole,
- Nitroalkene,
- Copper,
- Inline
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