Citation: Xi Huai Qiang, Zhi Hui Gao, Xue Chuan Wang, Jian Zheng Li, Hui Zong, Chi Min Du. Salicyaldehyde-based fluorescent sensors with high sensitivity for amino acids[J]. Chinese Chemical Letters, ;2011, 22(8): 985-988. doi: 10.1016/j.cclet.2011.03.005 shu

Salicyaldehyde-based fluorescent sensors with high sensitivity for amino acids

a Shaanxi University of Science and Technology, Xian 710021, China;
b Beijing Fanbo Biochemical Company, Beijing 100000, China

Received Date: 15 November 2010

Fund Project: The authors wish to thank the National Natural Science Foundation of China (No. 20876090), the Foundation for Research Initiation of Shaanxi University of Science & Technology (No. BJ09-15) and Foundation for Innovative Research Team of Shaanxi University of Science & Technology (No. TD09-04) for financial support.

Structurally simple salicylaldehyde-based fluorescent sensors for amino acids have been obtained by one-step or two-step synthesis. These sensors show significant fluorescence enhancement in the presence of many amino acids at concentrations as low as 10 ^-5 mol/L. The reversible reaction of the aldehydes with amino acids to form imines in aqueous solution is proposed to account for the observed fluorescence enhancement.
- Amino acids,
- Fluorescent sensors,
- Simple,
- Highly sensitive
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