Citation: Kaveh Parvanak Boroujeni, Kamran Parvanak. Efficient and solvent-free synthesis of bis-indolylmethanes using silica gel supported aluminium chloride as a reusable catalyst[J]. Chinese Chemical Letters, ;2011, 22(8): 939-942. doi: 10.1016/j.cclet.2011.01.039 shu

Efficient and solvent-free synthesis of bis-indolylmethanes using silica gel supported aluminium chloride as a reusable catalyst

Kaveh Parvanak Boroujeni ^a, ,
Kamran Parvanak ^b

a Department of Chemistry, Shahrekord University, Shahrekord 115, Iran;
b Islamic Azad University, Shahr-e-Rey Branch, Iran

Received Date: 15 November 2010

Stable and non-hygroscopic silica gel supported aluminium chloride (SiO₂-AlCl₃), which is prepared easily from cheap and commercially available compounds was found to be an environmentally friendly heterogeneous catalyst for the condensation of indole with aldehydes and ketones to afford bis-indolylmethanes at room temperature under solvent-free conditions. The catalyst can be reused up to five times after simple washing with ether.
- Bis-indolylmethanes,
- Indole,
- Carbonyl compounds,
- Silica gel,
- Aluminium chlorid
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