Citation: Dai Lin Liu, Xue Zhang, Shu Ping Wang, Nai Li Wang, Xin Sheng Yao. A new triterpenoid saponin from the roots of Ardisia crenata[J]. Chinese Chemical Letters, ;2011, 22(8): 957-960. doi: 10.1016/j.cclet.2011.01.027 shu

A new triterpenoid saponin from the roots of Ardisia crenata

a Tianjin Key Laboratory for Biomarkers of Occupational and Environmental Hazard, Tianjin 300162, China;
b Department of Pharmacognosy, Medical College of Chinese People's Armed Police Forces, Tianjin 300162, China;
c Department of Natural Products Chemistry, Shenyang Pharmaceutical University, Shenyang 110016, China

Received Date: 1 September 2010

A new triterpenoid saponin, 3β-O-{β-D-glucopyranosyl-(1→4)-[β-D-glucopyranosyl-(1→2)]-α-L-arabinopyranosyl}-16α, 28-dihydroxyolean-12-en-30-oic acid 30-O-β-D-glucopyranosyl ester (ardisicrenoside N, 1), together with two known saponins, ardisicrenoside C (2) and D (3), were isolated from the roots of Ardisia crenata Sim. Their structures were elucidated by extensive spectral analysis and chemical evidences. Saponins 1 showed cytotoxicity against MCI-7 and NCI-H460 cancer cell lines at 11.0 μmol/L and 22.1 μmol/L in vitro.
- Ardisia crenata Sims,
- Ardisicrenoside N,
- Cytotoxicity
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