Citation: Meng Gao, Cui Fen Lu Gui Chun Yang, Zu Xing Chen. A novel approach for synthesis of 3-amino-5-aryl-2,5-dihydropyridazines using onium salt as soluble support[J]. Chinese Chemical Letters, ;2011, 22(7): 823-826. doi: 10.1016/j.cclet.2010.12.055 shu

A novel approach for synthesis of 3-amino-5-aryl-2,5-dihydropyridazines using onium salt as soluble support

Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecule & School of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, China

Received Date: 29 October 2010

Fund Project: We gratefully acknowledge the Natural Sciences Foundation of Hubei province in China (Nos.2007ABA031 and 2008CDA078).

In this work it was presented an application of task specific onium salt as soluble support for the synthesis of 3-amino-5-ary 1-2,5-dihydropyridazines. This soluble support is of wide applicability and combines advantages of solid phase synthesis without its limitations with those of solution phase chemistry. After a simple washing step, products were cleaved from the supports and obtained in good yields.
- Onium salt,
- Support,
- Synthesis,
- Pyridazines
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