Citation: Ren Hua Zheng, Hai Chang Guo, Hua Jiang Jiang, Ke Hui Xu, Bei Bei Liu, Wei Lin Sun, Zhi Quan Shen. A new and convenient synthesis of phendiones oxidated by KBrO₃/H₂SO₄ at room temperature[J]. Chinese Chemical Letters, ;2010, 21(11): 1270-1272. doi: 10.1016/j.cclet.2010.05.030 shu

A new and convenient synthesis of phendiones oxidated by KBrO₃/H₂SO₄ at room temperature

a Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China;
b School of Pharmaceutical and Chemical Engineering, Taizhou University, Taizhou 317000, China

Received Date: 9 March 2010

Fund Project: We are grateful for the financial support from National Natural Science Foundation (No.20674071) and Provincial Natural Science Foundation of Zhejiang (No.Y4090281).

A new method is described to synthesize phendione derivatives from 1, 10-phenanthrolines using potassium bromate and 60%sulfuric acid as oxidant, which was easily applicable to scale-up. The reaction conditions are mild and the yields are excellent. The target compounds have been characterized by ¹H NMR, and IR.
- Pbendione,
- 1,10-Phenanthroline,
- KBrO₃/H₂SO₄,
- Synthesis
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