Citation: Xiang Juan Cui, Ying Ying Lu, Min Zhao, Shan Qian, Yong Wu. The new shortcut synthesis of 8-oxocoptisine[J]. Chinese Chemical Letters, ;2010, 21(11): 1281-1282. doi: 10.1016/j.cclet.2010.05.019 shu

The new shortcut synthesis of 8-oxocoptisine

Key Laboratory of Drug Targeting of Education Ministry, West China School of Pharmacy, Sichuan University, Chengdu 610041, China

Received Date: 24 February 2010

8-Oxocoptisine 1, a natural protoberberine alkaloid, can be more easily achieved starting from readily available and inexpensive berberine hydrochlorate 2. The structure of the target compound 1 was confirmed by melting point, ¹H NMR, IR, MS and elemental analysis.
- 8-Oxoeoptisine,
- Protobetrberine alkaloid,
- Berberine hydrochlorate,
- Synthesis
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