Citation:
Swapnil S. Sonar, Kiran F. Shelke, Gopal K. Kakade, Bapurao B. Shingate, Murlidhar S. Shingare. Alum:An efficient catalyst for one-pot synthesis of α-aminophosphonates[J]. Chinese Chemical Letters,
;2009, 20(9): 1042-1046.
doi:
10.1016/j.cclet.2009.04.024
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Alum (KAl(SO 4) 2·12H 2O) is an inexpensive, efficient, non-toxic and mild catalyst for the one-pot synthesis of α-aminophosphonates.A three component reaction of an aldehyde/ketone, an amine and triethyl phosphite was carried out under solvent-free conditions to afford the corresponding a-aminophosphonates in short reaction times and high yields with the green aspects by avoiding toxic catalysts and solvents.
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Keywords:
- Alum,
- α-Aminophosphonates,
- Aldehyde/ketone,
- Amine,
- Triethyl phosphite,
- Solvent-free
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