Citation: Jian Feng Zhou, Gui Xia Gong, Kun Bao Shi, San Jun Zhi. Catalyst-free and solvent-free method for the synthesis of quinoxalines under microwave irradiation[J]. Chinese Chemical Letters, ;2009, 20(6): 672-675. doi: 10.1016/j.cclet.2009.02.007 shu

Catalyst-free and solvent-free method for the synthesis of quinoxalines under microwave irradiation

a Department of Chemistry, Huaiyin Teachers College, Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials, Huaian 223300, China;
b School of Chemistry and Chemical Engineering, Key Laboratory of Organic Synthesis of Jiangsu Province, Suzhou University, Suzhou 215123, China

Received Date: 10 November 2008

Fund Project: We thank the Jiangsu Key Laboratory for Chemistry of Low-Dimensional Materials for financial support (No.JSKC07041).

A facile procedure for the synthesis of quinoxalines is being reported starting from benzil and 1,2-diaminobenzene. The reactions were carried out catalyst-free, solvent-free and under microwave irradiation conditions in high yield (84-98%) with short time (3-6 min) and environmental benign, as well as convenient operation. The structures of all the compounds have been confirmed on the basis of their IR, ¹H NMR, and/or ¹³C NMR, mass spectral data.
- Quinoxaline,
- Benzil,
- 1,2-Diaminobenzene,
- Catalyst-free,
- Solvent-free,
- Microwave irradiation
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