Citation: Zhi Gang Zhao, Xing Li Liu, Yi Zhong. Design and synthesis of novel chiral molecular tweezers based on deoxycholic acid[J]. Chinese Chemical Letters, ;2008, 19(9): 1051-1054. doi: 10.1016/j.cclet.2008.06.015 shu

Design and synthesis of novel chiral molecular tweezers based on deoxycholic acid

College of Chemistry and Environmental Protection Engineering, Southwest University for Nationalities, Chengdu 610041, China

Received Date: 20 March 2008

A novel type of chiral molecular tweezers has been designed and synthesized by using deoxycholic acid as backbone and ethanoyl and the chiral unsymmetrical urea unit as arms. Their structures were characterized by ¹H NMR, IR, MS spectra and elemental analysis. These molecular tweezers showed good binding ability for neutral molecules and chiral molecules.
- Molecular tweezer,
- Deoxycholic acid,
- Synthesis,
- Molecular recognition
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