Citation: Xiao Ping Chen, Zhi Ming Zhou, Hao Yuan, Zi Hui Meng. Preparation and chiral recognition of a novel chiral stationary phase for HPLC,based on mono(6^A-N-1-(2-hydroxyl)-phenylethylimino-6^A-deoxy)-β-cyclodextrin and covalently bonded silica gel[J]. Chinese Chemical Letters, ;2008, 19(7): 797-800. doi: 10.1016/j.cclet.2008.04.045 shu

Preparation and chiral recognition of a novel chiral stationary phase for HPLC,based on mono(6^A-N-1-(2-hydroxyl)-phenylethylimino-6^A-deoxy)-β-cyclodextrin and covalently bonded silica gel

School of Chemical Engineering and the Environment, Beijing Institute of Technology, Beijing[4_TD$DIF] 100081, China

Received Date: 25 February 2008

Fund Project: Financial support from the National Natural Science Foundation of China (No.20572009) is gratefully acknowledged.

A novel chiral stationary phase (CSP) was prepared by immobilizing mono(6^A-N-1-(2-hydroxyl)-phenylethylimino-6^A-deoxy)-β-cyclodextrin onto the surface of silica gel via a longer spacer.This chiral stationary phase exhibited good enantios electivity for a variety of chiral compounds under reversed-phase conditions.
- Cyclodextrin,
- Enantioseparation,
- Chirai stationary phase,
- Ferrocene derivatives
1. [1]
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2. [2]
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3. [3]
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4. [4]
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5. [5]
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6. [6]
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7. [7]
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8. [8]
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9. [9]
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10. [10]
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11. [11]
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12. [12]
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13. [13]
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14. [14]
  Jiaojiao Yang , Shaokun Yang , Wei Cheng , Jie Wu , Haijing Qu , Han Chen , Zhiran Duan , Yuqing Pan , Ning Wang , Chao Wang , Jian Gao , Bai Xiang , Xiangdong Xue . Self-assembled cyclodextrin-porphyrin nanoplatform for synergistic chemo-phototherapy and targeted delivery of camptothecin against breast cancer. Chinese Chemical Letters, 2026, 37(4): 111901-. doi: 10.1016/j.cclet.2025.111901
15. [15]
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16. [16]
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17. [17]
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18. [18]
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19. [19]
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20. [20]
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