Citation: Hai Qian, Wen Long Huang, Xiao Ming Wu, Hui Bin Zhang, Jin Pei Zhou, Wen Cai Ye. A new isochroman-4-one derivative from the peel of Musa sapientum L.and its total synthesis[J]. Chinese Chemical Letters, ;2007, 18(10): 1227-1230. doi: 10.1016/j.cclet.2007.07.020 shu

A new isochroman-4-one derivative from the peel of Musa sapientum L.and its total synthesis

a Center of Drug Discovery, China Pharmaceutical University, Nanjing 210009, China;
b Department of Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, China;
c Department of Phytochemistry, China Pharmaceutical University, Nanjing 210009, China

Received Date: 28 April 2007

Fund Project: We thanked associate professor Ji Hua Fu for testing anti-hypertensive activity of the compound 1.

A new isochroman-4-one, 7, 8-dihydroxy-3-methylisochroman-4-one was isolated from water soluble fraction of Musa sapientum L. Its structure was determined by spectroscopic evidences and its total synthesis has also been reported. The compound showed potent antihypertensive activity.
- Isochroman-4-one,
- Musa sapientum L.,
- Isolation,
- Total synthesis
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