Citation: Xu Lin Tan, Shi Cong Hou, Qing Hua Bian, Min Wang. Synthesis of novel chiral stationary phases for high-performance liquid chromatography[J]. Chinese Chemical Letters, ;2007, 18(4): 461-464. doi: 10.1016/j.cclet.2007.02.010 shu

Synthesis of novel chiral stationary phases for high-performance liquid chromatography

College of Science, China Agricultural University, Beijing 100094, China

Received Date: 29 November 2006

Fund Project: Financial support by the National Natural Science Foundation of China (No. 20472111) is gratefully acknowledged.

Three novel chiral selectors 4a-c were synthesized from (S)-amino acids and (R)-1-phenyl-2-(4-methylphenyl)ethylamine. 4a-c were connected to 3-aminopropylsilanized silica gel to be used as the chiral stationary phase for HPLC. Five amino acid derivatives and two pyrethroid insecticides were fairly resolved on these three new chiral stationary phases under normal phase condition.
- Enantioseparation,
- Chiral stationary phase,
- Amino acid derivatives,
- Pyrethroid insecticides
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