Citation: Wei Wei He, Xing Wang Zhou, Jian Quan Lu. Capillary electrophoresis-chemiluminecence detection of levodopa and benserazide in Medopar tablet[J]. Chinese Chemical Letters, ;2007, 18(1): 91-93. doi: 10.1016/j.cclet.2006.11.034 shu

Capillary electrophoresis-chemiluminecence detection of levodopa and benserazide in Medopar tablet

a College of Chemistry, Central China Normal University, Wuhan 430079, China;
b Hubei Key Laboratory of Bioanalytical Technology, Hubei Normal University, Huangshi 435002, China

Received Date: 16 June 2006

Fund Project: This work was supported by Science Foundation of the National Education Ministry (No. 206096) and Education Department of Hubei Province (No. Z200522002).

A novel method for the simultaneous determination of benserazide and levodopa using capillary electrophoresis (CE)-chemiluminescence (CL) has been developed. Under the optimal conditions, the detection limits (S/N=3) were 1.85 μg/mL for benserazide and 0.12 μg/mL for levodopa. This method was successfully applied to the determination of benserazide and levodopa in Medopar tablet, the results showed that the detected values are in accordance with those by official methods.
- Benserazide,
- Levodopa,
- Capillary electrophoresis,
- Chemiluminescence
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