Citation: Lingheng Kong, Fang Xie, Songjie Yu, Zisong Qi, Xingwei Li. Rh(III)-catalyzed coupling of nitrones with alkynes for the synthesis of indolines[J]. Chinese Journal of Catalysis, ;2015, 36(7): 925-932. doi: 10.1016/S1872-2067(15)60866-X shu

Rh(III)-catalyzed coupling of nitrones with alkynes for the synthesis of indolines

1.
Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, Liaoning, China

Corresponding author: Xingwei Li,
Received Date: 22 April 2015
Available Online: 30 April 2015
Fund Project: 国家自然科学基金(21272231, 21472186, 21372266). (21272231, 21472186, 21372266)

Rh-catalyzed redox-neutral coupling between N-aryl nitrones and alkynes has been achieved under relatively mild conditions. The reaction proceeded via C-H activation at the N-aryl ring with subsequent O-atom transfer, affording trisubstituted indolines in good chemoselectivity and moderate to good diasteroselectivity.
- Rhodium(III),
- Carbon-hydrogen activation,
- Oxygen-atom transfer,
- Nitrogen-aryl nitrones
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