以多齿席夫碱HL(N′-(6-甲氧基吡啶-2-亚甲基)吡啶-2-甲酰肼)为配体，通过溶剂热法与Ho(NO₃)₃·6H₂O和NaN₃反应，成功制备了一例叠氮桥联的新型四核稀土配合物[Ho₄(L)₄(NO₃)₂(N₃)₂(μ₂-N₃)₄]·CH₃OH (1)。单晶X射线衍射分析表明：配合物1的结构主要由4个Ho(Ⅲ)离子、4个席夫碱配体L^-、2个NO₃^-、2个N₃^-及4个μ₂-N₃^-组成。在配合物的结构中，4个Ho(Ⅲ)离子通过4个μ₃-N₃^-和4个μ₂-O原子相互连接，构成一个具有平行四边形构型的Ho₄核心。利用循环伏安法、凝胶电泳法、紫外吸收光谱法以及荧光光谱法对配合物1与小牛胸腺DNA之间的相互作用进行了系统研究。实验结果一致表明，该配合物与小牛胸腺DNA通过插入模式发生结合。

A tetranuclear Ho(Ⅲ)-based complex [Ho₄(L)₂(dbm)₆(CH₃O)₄] (1) was synthesized via solvothermal methods, where HL=(E)-2-hydroxy-3-methoxy-N′-[(6-methoxypyridin-2-yl)methylene]benzohydrazide and Hdbm=dibenzoylmethane. Structural characterization revealed that this complex is composed of four Ho³⁺ ions, six dbm^- ions, two L^- ions, and four coordinated CH₃O^- ions. The interaction mechanisms between ligand HL, 1 and calf thymus DNA (CT-DNA) were investigated by using UV-Vis spectroscopy, fluorescence titration, and cyclic voltammetry. The results indicated that 1 can interact with DNA via intercalation. Catalytic tests showed that 1 exhibits remarkable catalytic activity, capable of catalyzing the cycloaddition reaction of CO₂ with epoxides and the Knoevenagel condensation reaction between malononitrile and aldehydes.