源起于发霉甜苜蓿，脱胎于生化实验室，华法林先生起初作为一种强力灭鼠毒药大杀四方。然而，在进入医药领域的道路上，他却因毒药的身份标签和种种流言而饱受质疑和反对。科学家们揭示了华法林抗凝血的机制，并证明了华法林抗凝治疗对患者的益处。从此，华法林先生以及他的衍生物们成为了抗凝治疗和防治鼠害的前线战士。

笔者在大学入学之初就受教于华彤文老师，后来跟随华老师做研究、搞教学、写教材，直至担任《大学化学》主编时依然听取华老师的教诲。在此文中分享40余年来近距离观察、感受和学习华老师严谨治学、勇于担当的教学与研究的态度和方法，期待我国的化学教育教学事业薪火相传，持续发展。

高效灭藻与生态安全之间的矛盾是光催化治理有害藻华(HABs)的关键瓶颈。传统铜基光催化剂虽具有灭藻效果，但常引发严重的二次污染与水生态毒性。为解决这一矛盾，我们通过将LaCoO₃ (LCO)钙钛矿八面体共价锚定于2,4,6-三羟基苯-1,3,5-三甲醛(TP)和2,5-二氨基-1,4-苯二硫醇二盐酸盐(DABDT)溶剂热聚合而成的PTP-DABDT酰胺-亚胺功能骨架上，构建了具有生物安全性的S型异质结光催化材料。飞秒瞬态吸收光谱(fs-TA)和原位光照X射线光电子能谱(XPS)等证实了内建电场(IEF)的形成。该电场驱动超快S型电荷转移，在保持强氧化还原电势的同时能够有效抑制载流子复合。因此，改良后的20LCO/PTP-DABDT复合材料展现出优异的“杀藻-净化”协同性能：在铜绿微囊藻中实现64.39%叶绿素a降解以抑制藻华增殖，同时降解藻细胞释放的微囊藻毒素。更重要的是，对比毒性分析揭示了范式转变——传统铜基杀藻剂会导致非靶标生物(花鲈)100%死亡，而本体系存活率始终高于90%。本研究提出开创性的“生态调控”策略，为兼顾高效灭藻与环境生物安全性提供了可持续解决方案。

The selective hydrogenation of α, β-unsaturated aldehydes/ketones enables precise control over product structures and properties by regulating hydrogen transport pathways and bond cleavage sequences to selectively reduce C=C or C=O bonds while preserving other functional groups within the molecule. This approach serves as a critical strategy for the directional synthesis of high-value molecules. However, achieving such selectivity remains challenging due to the thermodynamic equilibrium and kinetic competition between C=O and C=C bonds in α, β-unsaturated systems. Consequently, constructing precisely targeted catalytic systems is essential to overcome these limitations, offering both fundamental scientific significance and industrial application potential. Metal-organic frameworks (MOFs) and their derivatives have emerged as innovative platforms for designing such systems, owing to their programmable topology, tunable pore microenvironments, spatially controllable active sites, and modifiable electronic structures. This review systematically summarizes the research progress of MOF-based catalysts for selective hydrogenation of α, β-unsaturated aldehydes/ketones in the last decade, with emphasis on the design strategy, conformational relationship, and catalytic mechanism, aiming to provide new ideas for the design of targeted catalytic systems for the selective hydrogenation of α, β-unsaturated aldehydes/ketones.