【大学化学】doi: 10.12461/PKU.DXHX202412089
李正名院士是我国著名的教育家、化学家和农药学家。在李先生逝世3周年之际,李正名奖学金捐赠暨首届颁奖仪式在南开大学举行。本文结合一部分典型的具体事例,对李正名先生的教育家精神和科学家精神进行了介绍,从中折射出他始终如一的坚定爱国信念和无私奉献精神。青年学子通过学习李先生的光辉事迹,可以深入了解老一辈科学家浓厚的家国情怀。本文有助于激励当代大学生厚植爱国主义理想与信念,增强自主创新意识和能力,立志为中华民族的伟大复兴贡献自己的全部力量。
【无机化学学报】doi: 10.11862/CJIC.20240329
Herein, a mesoporous magnetic nanocarrier containing disulfide bonds (NH2-SMNPs) was developed to improve the efficacy of tumor treatment and reduce side effects. After loading the carrier with doxorubicin (DOX), a nontoxic pullulan oxide was used as a gating material to form the oSMNPs/DOX nanodrug. This nanodrug exhibited uniform dispersion, good drug-loading capacity, and high saturation magnetization, enabling pH/glutathione (GSH) dual-responsive drug release in the tumor microenvironment, with a release rate as high as 81.53%. Furthermore, this nanodrug demonstrated good biocompatibility, effective capability to kill cancer cells, and competent cellular uptake ability.
