Citation: Li Jing FANG, Chen Xi ZHANG, Jin Chun CHEN, Guo Jun ZHENG, Yu Lin LI. Total Synthesis of Two 4, 5-Dioxo-seco-eudesmane Sesquiterpenes[J]. Chinese Chemical Letters, ;2005, 16(5): 569-571. shu

Total Synthesis of Two 4, 5-Dioxo-seco-eudesmane Sesquiterpenes

State Key Laboratory of Applied Organic Chemistry, Institute of Organic Chemistry, Lanzhou University, Lanzhou 730000

Received Date: 26 May 2004

Fund Project: This work was financially supported by the National Natural Science Foundation of China (No. 20272021).

A facile synthetic route to two seco-eudesmane, 4, 5-dioxo-10-epi-4, 5-seco-γeudesmane (1) and 4, 5-dioxo-10-epi-4, 5-seco-γ-eudesmol (2) from (+)-dihydrocarvone has been described. Avoiding expensive reagents, this highly economic method especially suits for the synthesis of 4, 5-seco-eudesman-type and ophianon-type sesquiterpenes with a double bond at position 11 and 12.
- Dihydrocarvone,
- 4,5-dioxo-seco-eudesmane,
- sesquiterpenes
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